Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Matthew L. MacDonald"'
Autor:
Irina L. Tourkova, Quitterie C. Larrouture, Silvia Liu, Jianhua Luo, Katherine E. Shipman, Kelechi M. Onwuka, Ora A. Weisz, Vladimir Riazanski, Deborah J. Nelson, Matthew L. MacDonald, Paul H. Schlesinger, Harry C. Blair
Publikováno v:
Bone Reports, Vol 21, Iss , Pp 101763- (2024)
Acid transport is required for bone synthesis by osteoblasts. The osteoblast basolateral surface extrudes acid by Na+/H+ exchange, but apical proton uptake is undefined. We found high expression of the Cl−/H+ exchanger ClC3 at the bone apical surfa
Externí odkaz:
https://doaj.org/article/bf7bf14d1982441993e7c2bea477f974
Autor:
Joshua M. Lorenz-Guertin, Nadya Povysheva, Caitlyn A. Chapman, Matthew L. MacDonald, Marco Fazzari, Aparna Nigam, Jessica L. Nuwer, Sabyasachi Das, Megan L. Brady, Katarina Vajn, Matthew J. Bambino, Susan T. Weintraub, Jon W. Johnson, Tija C. Jacob
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106248- (2023)
Benzodiazepine (BZ) drugs treat seizures, anxiety, insomnia, and alcohol withdrawal by potentiating γ2 subunit containing GABA type A receptors (GABAARs). BZ clinical use is hampered by tolerance and withdrawal symptoms including heightened seizure
Externí odkaz:
https://doaj.org/article/ad34633e407d4057b7e50eb452454154
Autor:
Aneta Przepiorski, Thitinee Vanichapol, Eugenel B. Espiritu, Amanda E. Crunk, Emily Parasky, Michael D. McDaniels, Dave R. Emlet, Ryan Salisbury, Cassandra L. Happ, Lawrence A. Vernetti, Matthew L. MacDonald, John A. Kellum, Thomas R. Kleyman, Catherine J. Baty, Alan J. Davidson, Neil A. Hukriede
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Hemolysis occurs in many injury settings and can trigger disease processes. In the kidney, extracellular hemoglobin can induce damage via several mechanisms. These include oxidative stress, mitochondrial dysfunction, and inflammat
Externí odkaz:
https://doaj.org/article/ed6e39b445874502af0c45f7b56b6278
Autor:
Rebecca A. DeGiosio, Melanie J. Grubisha, Matthew L. MacDonald, Brandon C. McKinney, Carlos J. Camacho, Robert A. Sweet
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Microtubule-associated protein 2 (MAP2) is the predominant cytoskeletal regulator within neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic marker. It influences microtubule dynamics and microtubule/actin interactio
Externí odkaz:
https://doaj.org/article/feebe467f7f44b968e4d7ae87d4f0f82
Autor:
Michael R. DeChellis-Marks, Yue Wei, Ying Ding, Cody M. Wolfe, Joshua M. Krivinko, Matthew L. MacDonald, Oscar L. Lopez, Robert A. Sweet, Julia Kofler
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Alzheimer's disease with psychosis (AD+P) is a heritable phenotypic variant of the disease which is associated with more rapid cognitive deterioration compared to Alzheimer's disease without psychosis (AD–P). Cognitive decline in AD correlates with
Externí odkaz:
https://doaj.org/article/e6b27b51a88f46158b5526005a488523
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Current treatments for psychosis in Alzheimer's disease (AD), a syndrome characterized by more rapid deterioration and reduced synaptic protein abundance relative to non‐psychotic AD, are inadequate. Fingolimod, a currently US
Externí odkaz:
https://doaj.org/article/acf8a87a373d4a5381a9785df1e6ead1
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Gene expression and translation have been extensively studied in human post-mortem brain tissue from subjects with psychiatric disease. Post-translational modifications (PTMs) have received less attention despite their implication by unbiased genetic
Externí odkaz:
https://doaj.org/article/42a801ed1be64c49abb4f8ea2c090463
Autor:
Stephanie Puig, Xiangning Xue, Ryan Salisbury, Micah A. Shelton, Sam-Moon Kim, Mariah A. Hildebrand, Jill R. Glausier, Zachary Freyberg, George C. Tseng, Anastasia K. Yocum, David A. Lewis, Marianne L. Seney, Matthew L. MacDonald, Ryan W. Logan
Publikováno v:
bioRxiv
Opioid craving and the vulnerability to relapse is associated with severe and persistent disruptions to sleep and circadian rhythms. Investigations into the cellular and molecular pathways in the human brain underlying the relationship between circad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1584146c908612def107465c817fc375
https://europepmc.org/articles/PMC10104116/
https://europepmc.org/articles/PMC10104116/
Autor:
Manish Kumar, R. B. Salisbury, Matthew L. MacDonald, Vasin Dumrongprechachan, Yevgenia Kozorovitskiy, Giulia Soto
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
The vertebrate brain consists of diverse neuronal types, classified by distinct anatomy and function, along with divergent transcriptomes and proteomes. Defining the cell-type specific neuroproteomes is important for understanding the development and
Autor:
Vasin Dumrongprechachan, Ryan B Salisbury, Lindsey Butler, Matthew L MacDonald, Yevgenia Kozorovitskiy
Publikováno v:
eLife. 11
Mammalian axonal development begins in embryonic stages and continues postnatally. After birth, axonal proteomic landscape changes rapidly, coordinated by transcription, protein turnover, and post-translational modifications. Comprehensive profiling