Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Matthew L Shapiro"'
Autor:
Hala Harony-Nicolas, Maya Kay, Johann du Hoffmann, Matthew E Klein, Ozlem Bozdagi-Gunal, Mohammed Riad, Nikolaos P Daskalakis, Sankalp Sonar, Pablo E Castillo, Patrick R Hof, Matthew L Shapiro, Mark G Baxter, Shlomo Wagner, Joseph D Buxbaum
Publikováno v:
eLife, Vol 6 (2017)
Mutations in the synaptic gene SHANK3 lead to a neurodevelopmental disorder known as Phelan-McDermid syndrome (PMS). PMS is a relatively common monogenic and highly penetrant cause of autism spectrum disorder (ASD) and intellectual disability (ID), a
Externí odkaz:
https://doaj.org/article/15f3de3779bb415499c0098f7ef83e2d
Autor:
Aditya Srinivasan, Arvind Srinivasan, Justin S. Riceberg, Michael R. Goodman, Kevin G. Guise, Matthew L. Shapiro
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113296- (2023)
Summary: Episodic memory requires the hippocampus and prefrontal cortex to guide decisions by representing events in spatial, temporal, and personal contexts. Both brain regions have been described by cognitive theories that represent events in conte
Externí odkaz:
https://doaj.org/article/2542c8112af14f0e8e916a4a807ef514
Autor:
Aditya Srinivasan, Justin S. Riceberg, Michael R. Goodman, Arvind Srinivasan, Kevin G. Guise, Matthew L. Shapiro
Publikováno v:
The Journal of Neuroscience. 43:3353-3364
Adapting flexibly to changing circumstances is guided by memory of past choices, their outcomes in similar circumstances, and a method for choosing among potential actions. The hippocampus (HPC) is needed to remember episodes, and the prefrontal cort
Publikováno v:
Hippocampus
When faced with changing contingencies, animals can use memory to flexibly guide actions, engaging both frontal and temporal lobe brain structures. Damage to the hippocampus (HPC) impairs episodic memory, and damage to the prefrontal cortex (PFC) imp
Publikováno v:
Current biology : CB. 32(15)
We often remember the consequences of past choices to adapt to changing circumstances. Recalling past events requires the hippocampus (HPC), and using stimuli to anticipate outcome values requires the orbitofrontal cortex (OFC).
Autor:
Hiroyuki Koike, Korey Kam, Julia Bateh, Daniel M. Brady, Andrew W Varga, Justin S. Riceberg, Kazuhiko Yamamuro, Hirofumi Morishita, Leah Waltrip, Kohei Yoshitake, Priscilla Maccario, Masato Sadahiro, Sarah E. McCraney, Michael P. Demars, Scott J. Russo, Mark G. Baxter, Peter H. Rudebeck, Elisa N. Falk, Matthew L. Shapiro, Keaven Caro, Christina Cho, Kevin J. Norman, Meghan E. Flanigan, Daisuke Kato, Ana Liang
Publikováno v:
Neuron. 109(7)
The frontal cortex, especially the anterior cingulate cortex area (ACA), is essential for exerting cognitive control after errors, but the mechanisms that enable modulation of attention to improve performance after errors are poorly understood. Here
Autor:
Matthew L. Shapiro
Publikováno v:
Nature neuroscience
There is accumulating evidence that the entorhinal-hippocampal network is important for temporal memory. However, relatively little is known about the precise neurobiological mechanisms underlying memory for time. In particular, whether the lateral e
Publikováno v:
Behavioral Neuroscience. 131:135-142
Degeneration of the nigrostriatal dopaminergic system in Parkinson's disease (PD) causes motor dysfunction and cognitive impairment, but the etiology of the cognitive deficits remains unclear. The present study investigated the behavioral effects of
Autor:
Matthew L. Shapiro, Justin S. Riceberg
Publikováno v:
The Journal of Neuroscience. 37:2010-2021
Memory can inform goal-directed behavior by linking current opportunities to past outcomes. The orbitofrontal cortex (OFC) may guide value-based responses by integrating the history of stimulus–reward associations into expected outcomes, representa