Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Matthew L Fero"'
Autor:
Daniel A Kuppers, Harry C Hwang, Aimee L Jackson, Peter S Linsley, Bruce E Clurman, Matthew L Fero
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e14758 (2011)
Mice lacking the p27(Kip1) Cdk inhibitor (Cdkn1b) exhibit increased susceptibility to lymphomas from the Maloney murine leukemia virus (M-MuLV), and exhibit a high frequency of viral integrations at Xpcl1 (Kis2), a locus on the X-chromosome. Xpcl1 en
Externí odkaz:
https://doaj.org/article/d72def821bff4b12b228cd374b202ed2
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7839 (2009)
BACKGROUND:The Myc oncoprotein, a transcriptional regulator involved in the etiology of many different tumor types, has been demonstrated to play an important role in the functions of embryonic stem (ES) cells. Nonetheless, it is still unclear as to
Externí odkaz:
https://doaj.org/article/c627c88b584247ac9cbf94f931ddc5a7
Autor:
Carrie M Garrett-Engele, Michael A Tasch, Harry C Hwang, Matthew L Fero, Roger M Perlmutter, Bruce E Clurman, James M Roberts
Publikováno v:
PLoS Genetics, Vol 3, Iss 12, p e219 (2007)
The cyclin-dependent kinase inhibitor p27(KIP1) is a tumor suppressor gene in mice, and loss of p27 protein is a negative prognostic indicator in human cancers. Unlike other tumor suppressors, the p27 gene is rarely mutated in tumors. Therefore misre
Externí odkaz:
https://doaj.org/article/3c113f238bd94d4da9eb5f2d05bb5853
Autor:
Harry C. Hwang, Daniel A. Kuppers, Lavanya Samraj, Matthew L. Fero, Thomas M. Schmitt, Bruce E. Clurman
Publikováno v:
Oncotarget
// Daniel A. Kuppers 1 , Thomas M. Schmitt 1 , Harry C. Hwang 2 , Lavanya Samraj 3 , Bruce E. Clurman 1 and Matthew L. Fero 4 1 Fred Hutchinson Cancer Research Center, Seattle, Washington, USA 2 Phenopath Laboratories, Seattle, Washington, USA 3 Univ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8ccc734b9b7019f85f06ba1cbc69e7
https://doi.org/10.18632/oncotarget.16932
https://doi.org/10.18632/oncotarget.16932
Autor:
Elihu H. Estey, Frederick R. Appelbaum, Vicky Sandhu, Matthew L. Fero, Min Fang, Kathleen Kroeger, Barry E. Storer, Christine M. Gronseth, Scott McElhone
Publikováno v:
Cancer. 121:2900-2908
BACKGROUND Chromosomal abnormalities are important in the diagnosis and prognosis of patients with acute myeloid leukemia (AML). Genomic microarray techniques detect recurrent copy-neutral loss of heterozygosity (cnLOH) in addition to copy number abe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfdd9bf8e12edd921d4bc4e1b9afc29a
https://doi.org/10.1002/cncr.29475
https://doi.org/10.1002/cncr.29475
Autor:
Richard A. Nash, Paul J. Martin, Mary E.D. Flowers, Jean E. Sanders, Shalini E. Pereira, Stephanie J. Lee, Barry E. Storer, Edus H. Warren, Frederick R. Appelbaum, Paul A. Carpenter, Matthew L. Fero, Marco Mielcarek, Rainer Storb, Hans-Peter Kiem, Yoshihiro Inamoto, Effie W. Petersdorf
Publikováno v:
Blood. 117:3214-3219
Risk factors for grades 2-4 acute graft-versus-host disease (GVHD) and for chronic GVHD as defined by National Institutes of Health consensus criteria were evaluated and compared in 2941 recipients of first allogeneic hematopoietic cell transplantati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e083c38af54d51dff73471d1d931094
https://doi.org/10.1182/blood-2010-08-302109
https://doi.org/10.1182/blood-2010-08-302109
Autor:
Christine M, Gronseth, Scott E, McElhone, Barry E, Storer, Kathleen A, Kroeger, Vicky, Sandhu, Matthew L, Fero, Frederick R, Appelbaum, Elihu H, Estey, Min, Fang
Publikováno v:
Cancer. 121(17)
Chromosomal abnormalities are important in the diagnosis and prognosis of patients with acute myeloid leukemia (AML). Genomic microarray techniques detect recurrent copy-neutral loss of heterozygosity (cnLOH) in addition to copy number aberrations. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba57203c88ad2c57202f5742caeae544
https://pubmed.ncbi.nlm.nih.gov/26033747
https://pubmed.ncbi.nlm.nih.gov/26033747
Publikováno v:
Nature Cell Biology. 7:172-178
Haematopoietic stem cells (HSCs) are capable of shifting from a state of relative quiescence under homeostatic conditions to rapid proliferation under conditions of stress. The mechanisms that regulate the relative quiescence of stem cells and its as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f0c002aa58a5d4fb9dcdac730dcec2
https://doi.org/10.1038/ncb1214
https://doi.org/10.1038/ncb1214
Autor:
Bruce E. Clurman, Yvon Bronkhorst, Erin Randel, Anton Berns, Matthew L. Fero, Carla P. Martins, Harry C. Hwang
Publikováno v:
Proceedings of the National Academy of Sciences. 99:11293-11298
The p27 Kip1 protein is a cyclin-dependent kinase inhibitor that blocks cell division in response to antimitogenic cues. p27 expression is reduced in many human cancers, and p27 functions as a tumor suppressor that exhibits haploinsufficiency in mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05509849eca1097e02473117b8233046
https://doi.org/10.1073/pnas.162356099
https://doi.org/10.1073/pnas.162356099
Autor:
Kevin Foley, Robert N. Eisenman, James M. Roberts, Andrew J. Deans, Matthew L. Fero, Grant A. McArthur, Carl R. Walkley
Publikováno v:
Molecular and Cellular Biology. 22:3014-3023
To understand how cellular differentiation is coupled to withdrawal from the cell cycle, we have focused on two negative regulators of the cell cycle, the MYC antagonist MAD1 and the cyclin-dependent kinase inhibitor p27(KIP1). Generation of Mad1/p27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c9bde06fed011a9d611e06d1faffa3
https://doi.org/10.1128/mcb.22.9.3014-3023.2002
https://doi.org/10.1128/mcb.22.9.3014-3023.2002