Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matthew L Andria"'
Publikováno v:
Neurochemical Research. 33:2054-2061
We have previously reported that the protein filamin A (FLA) binds to the carboxyl tail of the mu opioid receptor (MOPr). Using human melanoma cells, which do not express filamin A, we showed that receptor down-regulation, functional desensitization
Autor:
Jacob M. Hiller, Natasa Ancevska-Taneva, Irma Onoprishvili, Hal K. Kramer, Matthew L. Andria, Eric J. Simon
Publikováno v:
Molecular Pharmacology. 64:1092-1100
The carboxyl tail of the human mu opioid receptor was shown to bind the carboxyl terminal region of human filamin A, a protein known to couple membrane proteins to actin. Results from yeast two-hybrid screening were confirmed by direct protein-protei
Publikováno v:
Biochemical Pharmacology. 60:781-792
The internalization of G-protein-coupled receptors (GPCRs), including the delta opioid receptor (δ-OR), has been shown to involve the phosphorylation of serine and threonine residues. However, recent studies suggest that these residues may not be th
Publikováno v:
Molecular Brain Research. 73:129-137
The cDNA coding for the bovine mu-opioid receptor has been cloned and sequenced. Conserved sequences from murine delta-receptor cDNA were used as primers in polymerase chain reaction (PCR) to amplify cDNA, prepared by reverse transcription of bovine
Autor:
George K Ehrlich, Matthew L Andria, Xin Zheng, Brigitte Kieffer, Theresa L Gioannini, Jacob M Hiller, Jeremy E Rosenkranz, Boris M Veksler, R Suzanne Zukin, Eric J Simon
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 76:269-277
Previous work suggested that sulfhydryl groups and disulfide bridges have important functions in opioid binding to the delta opioid receptor. The question regarding which cysteines are essential for ligand binding was approached by replacement of cys
Publikováno v:
Journal of Biological Chemistry. 266:14597-14602
TAPA-1 (the target of an antiproliferative antibody) is a 26-kDa cell surface protein expressed on most human cell lines. TAPA-1 is a member of an evolutionarily related family of cell surface proteins all of which contain four transmembrane domains.
Autor:
Matthew L. Andria, Larry W. Kwak, Dale T. Umetsu, Shuji Takahashi, David G. Maloney, Rachel Oren, Michael J. Campbell, Andrew D. Zelenetz, Laura J. Esserman, Richard A. Miller, Thomas T. Chen, Ronald Levy, Shoshana Levy, Sherri L. Brown, David W. Bahler
Publikováno v:
Annals of Oncology. 2:115-122
Human follicular lymphoma can be viewed as a malignancy in evolution. Since this disease is composed of a clonal population of B lymphocytes all expressing a given immunoglobulin light chain and heavy chain, it seems possible that the initial transfo
Publikováno v:
Brain research. 1081(1)
A yeast two-hybrid screen, using the carboxyl tail of the human mu opioid receptor as bait and a human brain cDNA library as target, indicated that the carboxyl terminal portion of hlj1, a member of the human heat shock protein 40 family, interacts w
Autor:
Matthew L. Andria, Eric J. Simon
Publikováno v:
Brain research. Molecular brain research. 91(1-2)
Analysis of the DNA sequence of the human μ-opioid receptor gene (MOR) revealed that a region overlapping the start codon was substantially homologous to a DNA element named the neurorestrictive suppressor element (NRSE) or restrictive element 1 (RE
Publikováno v:
Brain research. Molecular brain research. 79(1-2)
Opioid receptors are known for their ability to activate diverse second messenger systems. Previously, we showed that selective delta-opioid agonists were able to induce the rapid tyrosine phosphorylation of delta-opioid receptors (delta-ORs) through