Zobrazeno 1 - 4
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pro vyhledávání: '"Matthew Kyle Hadden"'
Publikováno v:
Burger's Medicinal Chemistry and Drug Discovery. :1-88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4721c6641183760a4f628996cfe40303
https://doi.org/10.1002/0471266949.bmc212.pub2
https://doi.org/10.1002/0471266949.bmc212.pub2
Autor:
Matthew Kyle Hadden
Publikováno v:
Expert Opinion on Therapeutic Patents. 23:345-361
The hedgehog (Hh) pathway is a developmental signaling pathway that plays a key role in directing cellular growth and tissue patterning during embryonic development. Dysregulation of Hh signaling has been linked to the development of a variety of hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcefb7b5bfb58f21c1bffa4027178fb
https://doi.org/10.1517/13543776.2013.757304
https://doi.org/10.1517/13543776.2013.757304
Autor:
Matthew Kyle Hadden, Upasana Banerjee
Publikováno v:
Expert opinion on drug discovery. 9(7)
The Hedgehog (Hh) signaling pathway is known to be dysregulated in several forms of cancer. Hence, specifically targeting this signaling cascade is a valid and promising strategy for successful therapeutic intervention. Several components within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4643fdc64ad9376ae3ea7fdb649b6c
https://pubmed.ncbi.nlm.nih.gov/24850423
https://pubmed.ncbi.nlm.nih.gov/24850423
Autor:
Steven Lemieux, Albert M. DeBerardinis, Matthew Kyle Hadden, Michele Miller, Upasana Banerjee
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(14)
A structure-activity relationship study to elucidate the structural basis for hedgehog (Hh) signaling inhibition by vitamin D3 (VD3) was performed. Functional and non-functional regions of VD3 and VD2 were obtained through straightforward synthetic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a62d7b32f66af18a9ced60f96cd73a5
https://pubmed.ncbi.nlm.nih.gov/22687748
https://pubmed.ncbi.nlm.nih.gov/22687748