Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Matthew Kiely"'
Autor:
Maryam H. Alsameen, Zhaoyuan Gong, Wenshu Qian, Matthew Kiely, Curtis Triebswetter, Christopher M. Bergeron, Luis E. Cortina, Mary E. Faulkner, John P. Laporte, Mustapha Bouhrara
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
PurposeNeurite orientation dispersion and density imaging (NODDI) provides measures of neurite density and dispersion through computation of the neurite density index (NDI) and the orientation dispersion index (ODI). However, NODDI overestimates the
Externí odkaz:
https://doaj.org/article/7a0382520b004f4580e0e949951dd35f
Autor:
Curtis Triebswetter, Matthew Kiely, Nikkita Khattar, Luigi Ferrucci, Susan M. Resnick, Richard G. Spencer, Mustapha Bouhrara
Publikováno v:
NeuroImage, Vol 251, Iss , Pp 118988- (2022)
Mounting evidence indicates that myelin breakdown may represent an early phenomenon in neurodegeneration, including Alzheimer's disease (AD). Understanding the factors influencing myelin synthesis and breakdown will be essential for the development a
Externí odkaz:
https://doaj.org/article/9447a961def34fde814e39974d5941f1
Autor:
Matthew Kiely, Curtis Triebswetter, Luis E. Cortina, Zhaoyuan Gong, Maryam H. Alsameen, Richard G. Spencer, Mustapha Bouhrara
Publikováno v:
NeuroImage, Vol 247, Iss , Pp 118727- (2022)
White matter (WM) microstructural properties change across the adult lifespan and with neuronal diseases. Understanding microstructural changes due to aging is paramount to distinguish them from neuropathological changes. Conducted on a large cohort
Externí odkaz:
https://doaj.org/article/362fa2e0c74d4dd2bdff893edc670afe
Autor:
Nikkita Khattar, Curtis Triebswetter, Matthew Kiely, Luigi Ferrucci, Susan M. Resnick, Richard G. Spencer, Mustapha Bouhrara
Publikováno v:
NeuroImage, Vol 239, Iss , Pp 118267- (2021)
Myelin loss and iron accumulation are cardinal features of aging and various neurodegenerative diseases. Oligodendrocytes incorporate iron as a metabolic substrate for myelin synthesis and maintenance. An emerging hypothesis in Alzheimer's disease re
Externí odkaz:
https://doaj.org/article/88609eb71426405a9b62c1dd670a622c
Autor:
Joseph S. R. Alisch, Matthew Kiely, Curtis Triebswetter, Maryam H. Alsameen, Zhaoyuan Gong, Nikkita Khattar, Josephine M. Egan, Mustapha Bouhrara
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The choroid plexus (CP) is an important cerebral structure involved in cerebrospinal fluid production and transport of solutes into the brain. Recent studies have uncovered the involvement of the CP in neurological disorders such as Alzheimer’s dis
Externí odkaz:
https://doaj.org/article/8351db2425e04bfe8a24a468c1dee653
Publikováno v:
Neurobiology of Aging. 124:104-116
Changes in myelination are a cardinal feature of brain development and the pathophysiology of several cerebral diseases, including multiple sclerosis and dementias. Advanced magnetic resonance imaging (MRI) methods have been developed to probe myelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d36592b70a603419435c55e91408dde
https://doi.org/10.1101/2023.03.07.23286946
https://doi.org/10.1101/2023.03.07.23286946
Autor:
Maryam H. Alsameen, Zhaoyuan Gong, Wenshu Qian, Matthew Kiely, Curtis Triebswetter, Christopher M. Bergeron, Luis E. Cortina, Mary E. Faulkner, John P. Laporte, Mustapha Bouhrara
PurposeNeurite orientation dispersion and density imaging (NODDI) provides measures of neurite density and dispersion through computation of the neurite density index (NDI) and the orientation dispersion index (ODI). However, NODDI overestimates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::587b9b080fd6eb58ec3f37c1ee861199
https://doi.org/10.1101/2023.03.06.23286818
https://doi.org/10.1101/2023.03.06.23286818
Autor:
Mary E Faulkner, John P Laporte, Zhaoyuan Gong, Mohammad A B S Akhonda, Curtis Triebswetter, Matthew Kiely, Elango Palchamy, Richard G Spencer, Mustapha Bouhrara
Publikováno v:
The Journals of Gerontology: Series A.
Mounting evidence indicates that abnormal gait speed predicts the progression of neurodegenerative diseases, including Alzheimer’s disease. Understanding the relationship between white matter integrity, especially myelination, and motor function is
Autor:
Zhaoyuan Gong, Mustapha Bouhrara, Matthew Kiely, Curtis Triebswetter, Maryam H. Alsameen, Luis E. Cortina, Richard W Kim
Publikováno v:
Magn Reson Imaging
Axonal demyelination is a cardinal feature of aging and age-related diseases. The g-ratio, mathematically defined as the inner-to-outer diameter of a myelinated axon, is used as a structural index of optimal axonal myelination and has been shown to r