Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Matthew K. Topham"'
Autor:
Keiko Seino, Tomoyuki Nakano, Toshiaki Tanaka, Yasukazu Hozumi, Matthew K. Topham, Kaoru Goto, Ken Iseki
Publikováno v:
FEBS Open Bio, Vol 14, Iss 2, Pp 300-308 (2024)
Expression of α‐smooth muscle actin (αSMA) is constitutive in vascular smooth muscle cells, but is induced in nonmuscle cells such as hepatic stellate cells (HSCs). HSCs play important roles in both physiological homeostasis and pathological resp
Externí odkaz:
https://doaj.org/article/3068bee3ba404d47bbc2cb2ea859d866
Autor:
Diana M. Stafforini, Matthew K. Topham, Mónica P. Revelo, Alison A. Gardner, Mariah Lohse, Tomoyuki Nakano, Ethan C. Reichert, Changxin Xu
PDF file - 63K, Differential PLA2G7 expression in colorectal adenocarcinomas versus normal tissues, as determined by immunohistochemical analyses reported in the literature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd3da55935c22c5a2563667f1de1384
https://doi.org/10.1158/0008-5472.22399896.v1
https://doi.org/10.1158/0008-5472.22399896.v1
Autor:
Diana M. Stafforini, Matthew K. Topham, Mónica P. Revelo, Alison A. Gardner, Mariah Lohse, Tomoyuki Nakano, Ethan C. Reichert, Changxin Xu
PDF file - 92K, Supplementary methodology, including materials utilized, siRNA sequences, a description of immunoblot and immunohistochemical procedures, and statistical considerations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f4f37d151331470cf47ee02afe9603
https://doi.org/10.1158/0008-5472.22399899.v1
https://doi.org/10.1158/0008-5472.22399899.v1
Autor:
Diana M. Stafforini, Matthew K. Topham, Mónica P. Revelo, Alison A. Gardner, Mariah Lohse, Tomoyuki Nakano, Ethan C. Reichert, Changxin Xu
PDF file - 122K, Protein phosphatases PP1 and PP2 do not rescue cPAF-induced de-phosphorylation of pAkt473
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fb2ef639ed80bdc0cb3a256a5f3d00
https://doi.org/10.1158/0008-5472.22399902.v1
https://doi.org/10.1158/0008-5472.22399902.v1
Autor:
Diana M. Stafforini, Matthew K. Topham, Mónica P. Revelo, Alison A. Gardner, Mariah Lohse, Tomoyuki Nakano, Ethan C. Reichert, Changxin Xu
PDF file - 144K, PKC inhibition does not affect cPAF-induced de-phosphorylation of pAkt473
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286abe762ab835a6c24f47e1c8ce7fec
https://doi.org/10.1158/0008-5472.22399905.v1
https://doi.org/10.1158/0008-5472.22399905.v1
Autor:
Diana M. Stafforini, Matthew K. Topham, Mónica P. Revelo, Alison A. Gardner, Mariah Lohse, Tomoyuki Nakano, Ethan C. Reichert, Changxin Xu
PDF file - 60K, cPAF-induced de-phosphorylation of pAKT473 does not require Gαi/ Gαo or PKA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fb451212291c6f7ca80844baa3b7b7
https://doi.org/10.1158/0008-5472.22399908.v1
https://doi.org/10.1158/0008-5472.22399908.v1
Publikováno v:
Cancer Translational Medicine, Vol 6, Iss 2, Pp 40-47 (2020)
Targeted therapies reduce growth of mutant epidermal growth factor receptor (EGFR) non-small cell lung cancers, but most patients develop drug resistance. This has led to efforts to develop additional therapies. We found abundant activation of the cy
Autor:
Divyanshi Jalan, Richard M. Epand, Grant M. Hatch, Vincent So, Mathieu Lemaire, Matthew K. Topham
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1861:1993-1999
The incorporation of glycerol into lipid was measured using SV40 transformed mouse embryo fibroblasts (MEFs) from either wild-type (WT) mice or from mice in which the epsilon isoform of diacylglycerol kinase (DGKe) was knocked out (DGKe−/−). We p
Publikováno v:
Advances in biological regulation. 75
Adipose tissue is a central site for energy storage in the form of triglyceride (TG). Under excess energy conditions, TG is synthesized by acylation of diacylglycerol (DG), whereas TG is broken down into DG and free fatty acid, which provide energy f
Autor:
Yasukazu Hozumi, Masashi Okada, Toshiaki Tanaka, Rieko Tsuchiya, Matthew K. Topham, Kiyoshi Iwazaki, Michiaki Takagi, Kaneyuki Kawamae, Ken Iseki, Kaoru Goto
Publikováno v:
Journal of Cellular Physiology. 232:617-624
Bone homeostasis is maintained by a balance between resorption of the bone matrix and its replacement by new bone. Osteoclasts play a crucially important role in bone metabolism. They are responsible for bone resorption under pathophysiological condi