Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Matthew K. Robinson"'
Autor:
John P. Dowling, Pavel A. Nikitin, Fang Shen, Halley Shukla, James P. Finn, Nirja Patel, Cezary Swider, Jamie L. Bingaman-Steele, Chris Nicolescu, Eden L Sikorski, Evan J. Greenawalt, Michael J. Morin, Matthew K. Robinson, Karen Lundgren, Benjamin C. Harman
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTImmune checkpoint inhibitors that overcome T cell suppressive mechanisms in tumors have revolutionized the treatment of cancer but are only efficacious in a small subset of patients. Targeting suppressive mechanisms acting on innate immune ce
Externí odkaz:
https://doaj.org/article/687ffc074dce4fcdb4a25e4af9665e76
Autor:
Stephanie C Pero, Aaron M Rosenfeld, Girja S Shukla, Linda Mei, Yujing Sun, Wenzhao Meng, David J Fournier, Seth P Harlow, Matthew K Robinson, David N Krag, Eline T Luning Prak, Benjamin C Harman
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 8, Pp n/a-n/a (2022)
Abstract Objectives B cell‐mediated immunity can be associated with favorable clinical outcomes in cancer patients. However, the mechanism and features of anti‐tumor immune responses are not well understood. In particular, how B cells expressing
Externí odkaz:
https://doaj.org/article/619dc58a0a8b4fbd8b000d47149c560f
Autor:
Jillian M. DiMuzio, Baron C. Heimbach, Raymond J. Howanski, John P. Dowling, Nirja B. Patel, Noeleya Henriquez, Chris Nicolescu, Mitchell Nath, Antonio Polley, Jamie L. Bingaman, Todd Smith, Benjamin C. Harman, Matthew K. Robinson, Michael J. Morin, Pavel A. Nikitin
Publikováno v:
Vaccine: X, Vol 8, Iss , Pp 100098- (2021)
Patients who recover from SARS-CoV-2 infections produce antibodies and antigen-specific T cells against multiple viral proteins. Here, an unbiased interrogation of the anti-viral memory B cell repertoire of convalescent patients has been performed by
Externí odkaz:
https://doaj.org/article/3838a23d47594e7298ad698becdb3b0c
Autor:
Matthew K. Robinson
Publikováno v:
Evangelical Quarterly. 92:293-311
This article analyses Paul’s argument regarding the reception of the Spirit and the creation of a new covenantal identity in Galatians 3:1–6:10 so as to illumine the provocative declaration in Gal. 3:28. Some scholars (e.g., Douglas Campbell) rea
Autor:
Pavel A. Nikitin, Jillian M. DiMuzio, John P. Dowling, Nirja B. Patel, Jamie L. Bingaman-Steele, Baron C. Heimbach, Noeleya Henriquez, Chris Nicolescu, Antonio Polley, Eden L. Sikorski, Raymond J. Howanski, Mitchell Nath, Halley Shukla, Suzanne M. Scheaffer, James P. Finn, Li-Fang Liang, Todd Smith, Nadia Storm, Lindsay G. A. McKay, Rebecca I. Johnson, Lauren E. Malsick, Anna N. Honko, Anthony Griffiths, Michael S. Diamond, Purnanand Sarma, Dennis H. Geising, Michael J. Morin, Matthew K. Robinson
Publikováno v:
Science Immunology. 7
Monoclonal antibodies are an efficacious therapy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, rapid viral mutagenesis led to escape from most of these therapies, outlining the need for an antibody cocktail with a bro
Autor:
Mathilde Poussin, Alba Rodriguez-Garcia, Matthew K. Robinson, Gregory P. Adams, Prannda Sharma, Alina C. Boesteanu, Daniel J. Powell, Sarah B. Gitto, Fiona Simpkins, Nicholas G. Minutolo, Dalia K. Omran
Publikováno v:
Mol Ther
The prognosis of patients diagnosed with advanced ovarian or endometrial cancer remains poor, and effective therapeutic strategies are limited. The Müllerian inhibiting substance type 2 receptor (MISIIR) is a transforming growth factor β (TGF-β) r
Autor:
Pavel A. Nikitin, Jillian M. DiMuzio, John P. Dowling, Nirja B. Patel, Jamie L. Bingaman-Steele, Baron C. Heimbach, Noeleya Henriquez, Chris Nicolescu, Antonio Polley, Eden L. Sikorski, Raymond J. Howanski, Mitchell Nath, Halley Shukla, Suzanne M. Scheaffer, James P. Finn, Li-Fang Liang, Todd Smith, Nadia Storm, Lindsay G. A. McKay, Rebecca I. Johnson, Lauren E. Malsick, Anna N. Honko, Anthony Griffiths, Michael S. Diamond, Purnanand Sarma, Dennis H. Geising, Michael J. Morin, Matthew K. Robinson
Using an unbiased interrogation of the anti-viral memory B cell repertoire of convalescent COVID-19 patients, we identified three human antibodies that when combined demonstrated both robust viral suppressive properties against all tested SARS-CoV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fca46853486ce71107671127e851ce01
https://doi.org/10.1101/2021.10.18.464900
https://doi.org/10.1101/2021.10.18.464900
Autor:
Jimson W D'Souza, Smitha Reddy, Lisa E Goldsmith, Irina Shchaveleva, James D Marks, Samuel Litwin, Matthew K Robinson
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112376 (2014)
Inappropriate signaling through the epidermal growth factor receptor family (EGFR1/ERBB1, ERBB2/HER2, ERBB3/HER3, and ERBB4/HER4) of receptor tyrosine kinases leads to unregulated activation of multiple downstream signaling pathways that are linked t
Externí odkaz:
https://doaj.org/article/de2f6ddec96a48f9bca90652df0b0d87
Autor:
John P Dowling, Pavel A Nikitin, Fang Shen, James P Finn, Nirja Patel, Cezary Swider, Jamie Steele, Halley Shukla, Matthew K Robinson, Karen Lundgren, Benjamin C Harman
Publikováno v:
Molecular Cancer Therapeutics. 20:LBA022-LBA022
Immune checkpoint inhibitors that overcome T cell suppressive mechanisms in tumors have revolutionized the treatment of cancer. However, therapies targeting innate immune cell subsets that orchestrate adaptive immune responses could significantly imp
Autor:
A. Weiskopf, Milan R. Uskokovic, Matthew K. Robinson, Gino J. Sasso, G. Satyanarayana Reddy, Caroline C. Flarakos, Guoshun Wang, Paul Vouros
Publikováno v:
Steroids. 119:18-30
Analogs of 1α,25-dihydroxyvitamin D3 (S1) with 20-epi modification (20-epi analogs) possess unique biological properties. We previously reported that 1α,25-dihydroxy-20-epi-vitamin D3 (S2), the basic 20-epi analog is metabolized into less polar met