Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Matthew Joseph Doyle"'
Autor:
Cavanaugh Pf, Michael S. Reddy, Jeffcoat Mk, William Buchanan, Michael P. Meredith, Matthew Joseph Doyle
Publikováno v:
Journal of Periodontal Research. 33:75-82
The inflammatory mediators prostaglandin E2 (PGE2) and interleukin-1 beta (IL-1 beta) play critical roles in the inflammatory process leading to alveolar bone and connective tissue loss in periodontal disease. Data from a previously published 6-month
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20c184635345610dfb9ee82ca8890743
https://doi.org/10.1111/j.1600-0765.1998.tb02295.x
https://doi.org/10.1111/j.1600-0765.1998.tb02295.x
Autor:
Gary Robert Kelm, N.V. Bapat, Steven Offenbacher, William Buchanan, J.G. Collins, Michael P. Meredith, S.M. Mankodi, Kenneth R. Wehmeyer, Douglas Joseph Dobrozsi, Matthew Joseph Doyle, Thomas H. Eichhold
Publikováno v:
Journal of Pharmaceutical Sciences. 85:842-847
Two clinical studies were conducted to determine the relative amounts of ketorolac detectable locally in the gingival crevicular fluid (GCF) and systemically in plasma after oral, topical drug administration. The rinse study compared topical administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9449d0370815832d65914475a9f5b9
https://doi.org/10.1021/js9505253
https://doi.org/10.1021/js9505253
Autor:
William Buchanan, Marjorie K. Jeffcoat, Michael S. Reddy, M.B. Goodale, S.L. Nelson, M.P. Meredith, Sandra J. Haigh, K.R. Wehmeyer, Matthew Joseph Doyle
Publikováno v:
Journal of Periodontology. 66:329-338
Systemic non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce alveolar bone loss in periodontitis. This study assesses the efficacy of a topical NSAID rinse, containing ketorolac tromethamine as the active agent. Adult periodontit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdeb037ac067fe037ac586a6aec86ed
https://doi.org/10.1902/jop.1995.66.5.329
https://doi.org/10.1902/jop.1995.66.5.329
Autor:
Ralph W. Farmer, Matthew Joseph Doyle, Maurice Edward Loomans, Gary Robert Kelm, Thomas H. Eichhold
Publikováno v:
Journal of Pharmaceutical Sciences. 82:847-850
It is recognized that some acidic nonsteroidal antiinflammatory drugs (NSAIDs) accumulate in the synovial fluids of inflamed joints. The distribution of tebufelone, a member of the di-tert-butylphenol class of NSAIDs, between rat plasma and paw tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927f70c69f52593a547d676beb3cfc12
https://doi.org/10.1002/jps.2600820819
https://doi.org/10.1002/jps.2600820819
Autor:
Steven P. Sirko, Steven M. Weisman, Charles A. Dinarello, Matthew Joseph Doyle, Ralf Schindler
Publikováno v:
European Journal of Immunology. 21:243-250
We examined the effect of tebufelone, a dual cyclooxygenase (CO)/5-lipoxygenase (LO) inhibitor, on the synthesis, secretion and gene expression of interleukin (IL) 1 beta and tumor necrosis factor (TNF)-alpha by human peripheral blood mononuclear cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835232d97e31060c12ab13dde82e6fd5
https://doi.org/10.1002/eji.1830210202
https://doi.org/10.1002/eji.1830210202
Publikováno v:
Biological Mass Spectrometry. 19:230-234
A capillary gas chromatographic/mass spectrometric method for the determination of tebufelone, a new anti-inflammatory drug, in plasma and rat paw tissue is described. Trideuteriated tubufelone was employed as an internal standard and the drug quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf70b00d0694163675b456c937b3dfa
https://doi.org/10.1002/bms.1200190405
https://doi.org/10.1002/bms.1200190405
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 527:59-66
The rate of peppermint oil absorption and excretion, following peroral administration, was determined by measuring urinary levels of menthol glucuronide. Menthol, a major component of peppermint oil, was liberated from its glucuronide metabolite by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aded6ef463aaa93e4a1c950d902e5aa6
https://doi.org/10.1016/s0378-4347(00)82083-6
https://doi.org/10.1016/s0378-4347(00)82083-6
Publikováno v:
Journal of dental research. 85(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6886e14d1d49d945dd99d89ef58009c
https://pubmed.ncbi.nlm.nih.gov/16723641
https://pubmed.ncbi.nlm.nih.gov/16723641
Autor:
Rose M. Deibel, Gene O. Kinnett, Ralph W. Farmer, William K. Sietsema, Thomas H. Eichhold, Matthew Joseph Doyle, Robert E. Smyth, Maurice Edward Loomans, Gary Robert Kelm
Publikováno v:
Journal of Pharmaceutical Sciences. 82:610-612
Tebufelone (NE-11740) is a member of the new di-tertbutylphenol class of anti-inflammatory agents. It exhibits good inhibitory activity against cyclooxygenase and 5-lipoxygenase in vitro. It also shows excellent anti-inflammatory activity and inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fa6dee2aa301ad6746db38f071b700
https://doi.org/10.1002/jps.2600820613
https://doi.org/10.1002/jps.2600820613
Autor:
Kenneth R. Wehmeyer, Thomas H. Eichhold, Rose M. Clear, Debra L. Kuhlenbeck, Barbara A. Hynd, Matthew Joseph Doyle, Steven M. Weisman, Chester W. Coggeshall
Publikováno v:
Agents and actions. 41(3-4)
Tebufelone is a novel nonsteroidal anti-inflammatory drug (NSAID), of the di-tert-butylphenol (DTBP) class, which displays potent anti-inflammatory, analgesic and anti-pyretic properties in a variety of animal models. In this report, the effects of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f146690c7b0b42de69eb204d4e5a793
https://pubmed.ncbi.nlm.nih.gov/7942323
https://pubmed.ncbi.nlm.nih.gov/7942323