Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Matthew J. Whitters"'
Autor:
Marina Kovaleva, Kenneth Saunders, Caroline J. Barelle, Matthew J. Whitters, Jiquan Zhang, Deborah Luxenberg, John Steven, Emma Cummins, Miguel F. Carvalho, Alfredo Darmanin-Sheehan, Ronan O’Dwyer
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Journal of Immunology Research
Journal of Immunology Research
Lymphocyte costimulation plays a central role in immunology, inflammation, and immunotherapy. The inducible T cell costimulator (ICOS) is expressed on T cells following peptide: MHC engagement with CD28 costimulation. The interaction of ICOS with its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b3534a19422f7eef7c47e6912dc79c
https://doaj.org/article/2040fb960ade4e4a81c4768f6494230b
https://doaj.org/article/2040fb960ade4e4a81c4768f6494230b
Autor:
Tianshu Zhang, Helen Zhou, Xiangfei Cheng, E. Rybak, A. Laaris, S. Fresnay, N. Sangrampurkar, E. Welty, A. M. Nagelin, Q. Feng, C. Avon, Matthew J. Whitters, Agnes M. Azimzadeh, R. M. O’Hara
Publikováno v:
American Journal of Transplantation. 11:1599-1609
Selective blockade of CD28 is a promising therapy to inhibit pathogenic alloimmunity. However, evaluation of this approach in transplantation has been very limited. Using a novel non-activating single-chain Fv-based reagent (α28scFv), we have invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611cda21c52de06c9def9ad9ee88a664
https://doi.org/10.1111/j.1600-6143.2011.03624.x
https://doi.org/10.1111/j.1600-6143.2011.03624.x
Autor:
Neil M. Wolfman, Jamila El-Baghdadi, Magali Audry, Miguel Galicchio, Jean-Laurent Casanova, Matthew J. Whitters, Luyan Liu, Mary Collins, Christine Bodemer, Hye Kyung Lim, Matthew Gumbleton, Jonathan Brooks, Laurent Abel, Capucine Picard, Saleh Al-Muhsen, Jill F. Wright, Maya Chrabieh, Antoine Toulon, Sophie Cypowyj, Laura Israel, Anne Puel, Jacinta Bustamante, Mélanie Migaud, Theresa Paradis
Publikováno v:
Science. 332:65-68
Chronic mucocutaneous candidiasis disease (CMCD) is characterized by recurrent or persistent infections of the skin, nails, and oral and genital mucosae caused by Candida albicans and, to a lesser extent, Staphylococcus aureus , in patients with no o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1f261571c414ea2de60aa113afff6d
https://doi.org/10.1126/science.1200439
https://doi.org/10.1126/science.1200439
Autor:
Emma Cummins, Alfredo Darmanin-Sheehan, Orla Cunningham, Deborah Luxenberg, Brian J. Fennell, Davinder Gill, Matthew J. Whitters, Laird Bloom, Fionnuala Mcaleese, Angela Widom
Publikováno v:
Journal of Immunological Methods. 339:38-46
Phage and ribosome display technologies have emerged as important tools in the high-throughput screening of protein pharmaceuticals. However, a challenge created by the implementation of such tools is the need to purify large numbers of proteins for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba060e91ce08a5c56f1a6527b726c0ec
https://doi.org/10.1016/j.jim.2008.07.016
https://doi.org/10.1016/j.jim.2008.07.016
Autor:
Samuel J. Goldman, Kyriaki Dunussi-Joannopoulos, Jill F. Wright, Riyez Karim, Lynette A. Fouser, Frann Bennett, Mary Collins, Matthew J. Whitters, Cara M. M. Williams, Spencer Liang, Andrew J. Long
Publikováno v:
The Journal of Immunology. 179:7791-7799
IL-17A and IL-17F are related homodimeric proteins of the IL-17 family produced by Th17 cells. In this study, we show that mouse Th17 cells also produce an IL-17F/A heterodimeric protein. Whereas naive CD4+ T cells differentiating toward the Th17 cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19c998dea8146e0370b73c7873df0f5
https://doi.org/10.4049/jimmunol.179.11.7791
https://doi.org/10.4049/jimmunol.179.11.7791
Autor:
Beatriz M. Carreno, Geoffrey L. Stephens, Mary Collins, Deborah Luxenberg, Matthew J. Whitters, Deborah A. Young, Ethan M. Shevach, Rebecca S. McHugh
Publikováno v:
The Journal of Immunology. 173:5008-5020
Nonactivated CD4+CD25+ regulatory T cells constitutively express glucocorticoid-induced TNFR family-related receptor (GITR), a TNFR family member whose engagement was presumed to abrogate regulatory T cell-mediated suppression. Using GITR−/− mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4911337bdbe3bbec65b3ccfca670a5
https://doi.org/10.4049/jimmunol.173.8.5008
https://doi.org/10.4049/jimmunol.173.8.5008
Autor:
Allen W. Cheever, Debra D. Donaldson, Michael J. Grusby, Mary Collins, Monica G. Chiaramonte, Mary E.P. Goad, Bruce A. Jacobson, Matthew J. Whitters, Thomas A. Wynn, Margaret M. Mentink-Kane, Anthony Wong
Publikováno v:
The Journal of Experimental Medicine
Highly polarized type 2 cytokine responses can be harmful and even lethal to the host if they are too vigorous or persist too long. Therefore, it is important to elucidate the mechanisms that down-regulate these reactions. Interleukin (IL)-13 has eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa03686b04d16769c060cddcdde742cb
https://doi.org/10.1084/jem.20020903
https://doi.org/10.1084/jem.20020903
Autor:
Michael J. Grusby, Wood Nancy L, Samuel J. Goldman, Joann S. Witek, Unger Michelle J, Takashi Tanaka, Marion T. Kasaian, Michael J. Eppihimer, Bruce A. Jacobson, Debra D. Donaldson, Joseph P. Sypek, Matthew J. Whitters, Mary Collins
Publikováno v:
The Journal of Experimental Medicine
Interleukin (IL)-13 has recently been shown to play important and unique roles in asthma, parasite immunity, and tumor recurrence. At least two distinct receptor components, IL-4 receptor (R)α and IL-13Rα1, mediate the diverse actions of IL-13. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9719eaeae3939238c125ad543d4dcc1
https://doi.org/10.1084/jem.20020906
https://doi.org/10.1084/jem.20020906
Publikováno v:
Immunologic Research. 28:131-140
Interleukin (IL)-21 is a new member of the type I cytokine superfamily. Although it is most homologous to IL-15, it has a unique receptor chain, IL-21R, that pairs with the gamma-common cytokine receptor chain. The first experiments examining the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9ea2692c697bbc1829b67004f25ddd
https://doi.org/10.1385/ir:28:2:131
https://doi.org/10.1385/ir:28:2:131
Autor:
Vikki L. Rodgers, Andrea L. Wurster, Michael J. Grusby, Abhay R. Satoskar, Mary Collins, Matthew J. Whitters, Deborah A. Young
Publikováno v:
The Journal of Experimental Medicine
The cytokine potential of developing T helper (Th) cells is directly shaped both positively and negatively by the cytokines expressed by the effector Th cell subsets. Here we find that the recently identified cytokine, interleukin (IL)-21, is prefere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b443e03575220fb74c141b4d717b91
https://doi.org/10.1084/jem.20020620
https://doi.org/10.1084/jem.20020620