Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Matthew J. Tarnowski"'
Autor:
Matthew J. Tarnowski, Mario Pansera
Publikováno v:
Journal of Responsible Innovation, Vol 11, Iss 1 (2024)
Synthetic biology predominantly follows a market-driven approach, both within the private sector and academia. We present a research journey undertaken by a synthetic biologist who received guidance from responsible innovation scholars, reflecting on
Externí odkaz:
https://doaj.org/article/7edb4c2515da4235997fde17c7561925
Publikováno v:
Royal Society Open Science, Vol 10, Iss 11 (2023)
The vast microbial biodiversity of soils is beginning to be observed and understood by applying modern DNA sequencing techniques. However, ensuring this potentially valuable information is used in a fair and equitable way remains a challenge. Here, w
Externí odkaz:
https://doaj.org/article/4262f9e5086546089252924ebb8ec21e
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Transcriptional terminators are generally viewed as hard endpoints for transcribing RNA polymerases. Here, the authors reimagine terminators as transcriptional valves with predictable read through. They engineer and characterize 1780 valves and use t
Externí odkaz:
https://doaj.org/article/48474565a21a425780934f569031621f
Autor:
Alice E. Williamson, Paul M. Ylioja, Murray N. Robertson, Yevgeniya Antonova-Koch, Vicky Avery, Jonathan B. Baell, Harikrishna Batchu, Sanjay Batra, Jeremy N. Burrows, Soumya Bhattacharyya, Felix Calderon, Susan A. Charman, Julie Clark, Benigno Crespo, Matin Dean, Stefan L. Debbert, Michael Delves, Adelaide S. M. Dennis, Frederik Deroose, Sandra Duffy, Sabine Fletcher, Guri Giaever, Irene Hallyburton, Francisco-Javier Gamo, Marinella Gebbia, R. Kiplin Guy, Zoe Hungerford, Kiaran Kirk, Maria J. Lafuente-Monasterio, Anna Lee, Stephan Meister, Corey Nislow, John P. Overington, George Papadatos, Luc Patiny, James Pham, Stuart A. Ralph, Andrea Ruecker, Eileen Ryan, Christopher Southan, Kumkum Srivastava, Chris Swain, Matthew J. Tarnowski, Patrick Thomson, Peter Turner, Iain M. Wallace, Timothy N. C. Wells, Karen White, Laura White, Paul Willis, Elizabeth A. Winzeler, Sergio Wittlin, Matthew H. Todd
Publikováno v:
ACS Central Science, Vol 2, Iss 10, Pp 687-701 (2016)
Externí odkaz:
https://doaj.org/article/389f0d71ee2a4fb79f8bb1da8028bfae
Autor:
Susanna Manrubia, José A. Cuesta, Jacobo Aguirre, Sebastian E. Ahnert, Lee Altenberg, Alejandro V. Cano, Pablo Catalán, Ramon Diaz-Uriarte, Santiago F. Elena, Juan Antonio García-Martín, Paulien Hogeweg, Bhavin S. Khatri, Joachim Krug, Ard A. Louis, Nora S. Martin, Joshua L. Payne, Matthew J. Tarnowski, Marcel Weiß
Publikováno v:
Physics of Life Reviews. 42:19-24
Autor:
Carina Johansson, Ola Engkvist, Amélie Barozet, Matthew J. Tarnowski, Per Olof Eriksson, Jarrod Walsh, J. Willem M. Nissink
Publikováno v:
Assay and drug development technologies. 16(3)
Discerning false positives from true actives in high-throughput screening (HTS) output is fraught with difficulty as the reason of anomalous activity seen for compounds is often not clear-cut. In this study, we introduce a novel medium-throughput NMR
Autor:
Matthew H. Todd, Sergio Wittlin, Kiaran Kirk, John P. Overington, Elizabeth A. Winzeler, Stuart A. Ralph, Francisco-Javier Gamo, Timothy N. C. Wells, Yevgeniya Antonova-Koch, Zoe Hungerford, Irene Hallyburton, Corey Nislow, Peter Turner, Benigno Crespo, Stefan L. Debbert, Sabine Fletcher, Luc Patiny, Jeremy N. Burrows, Sandra Duffy, Chris Swain, Soumya Bhattacharyya, Sanjay Batra, Jonathan B. Baell, Julie Clark, Patrick Thomson, Andrea Ruecker, Christopher Southan, Frederik Deroose, Murray N. Robertson, Kumkum Srivastava, Marinella Gebbia, Susan A. Charman, Iain M. Wallace, Eileen Ryan, Karen L. White, Anna Lee, George Papadatos, Paul Willis, Guri Giaever, James Pham, Laura White, Maria J. Lafuente-Monasterio, Paul M. Ylioja, Alice E. Williamson, Harikrishna Batchu, Michael J. Delves, Adelaide S. M. Dennis, Vicky M. Avery, Matin Dean, Félix Calderón, R. Kiplin Guy, Matthew J. Tarnowski, Stephan Meister
Publikováno v:
ACS Central Science, Vol 2, Iss 10, Pp 687-701 (2016)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Williamson, A E, Ylioja, P M, Robertson, M N, Antonova-Koch, Y, Avery, V, Baell, J B, Batchu, H, Batra, S, Burrows, J N, Bhattacharyya, S, Calderon, F, Charman, S A, Clark, J, Crespo, B, Dean, M, Debbert, S L, Delves, M, Dennis, A S M, Deroose, F, Duffy, S, Fletcher, S, Giaever, G, Hallyburton, I, Gamo, F-J, Gebbia, M, Guy, R K, Hungerford, Z, Kirk, K, Lafuente-Monasterio, M J, Lee, A, Meister, S, Nislow, C, Overington, J P, Papadatos, G, Patiny, L, Pham, J, Ralph, S A, Ruecker, A, Ryan, E, Southan, C, Srivastava, K, Swain, C, Tarnowski, M J, Thomson, P, Turner, P, Wallace, I M, Wells, T N C, White, K, White, L, Willis, P, Winzeler, E A, Wittlin, S & Todd, M H 2016, ' Open Source Drug Discovery : Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles ', ACS Central Science, vol. 2, no. 10, pp. 687-701 . https://doi.org/10.1021/acscentsci.6b00086
ACS Central Science
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Williamson, A E, Ylioja, P M, Robertson, M N, Antonova-Koch, Y, Avery, V, Baell, J B, Batchu, H, Batra, S, Burrows, J N, Bhattacharyya, S, Calderon, F, Charman, S A, Clark, J, Crespo, B, Dean, M, Debbert, S L, Delves, M, Dennis, A S M, Deroose, F, Duffy, S, Fletcher, S, Giaever, G, Hallyburton, I, Gamo, F-J, Gebbia, M, Guy, R K, Hungerford, Z, Kirk, K, Lafuente-Monasterio, M J, Lee, A, Meister, S, Nislow, C, Overington, J P, Papadatos, G, Patiny, L, Pham, J, Ralph, S A, Ruecker, A, Ryan, E, Southan, C, Srivastava, K, Swain, C, Tarnowski, M J, Thomson, P, Turner, P, Wallace, I M, Wells, T N C, White, K, White, L, Willis, P, Winzeler, E A, Wittlin, S & Todd, M H 2016, ' Open Source Drug Discovery : Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles ', ACS Central Science, vol. 2, no. 10, pp. 687-701 . https://doi.org/10.1021/acscentsci.6b00086
ACS Central Science
The development of new antimalarial compounds remains a pivotal part of the strategy for malaria elimination. Recent large-scale phenotypic screens have provided a wealth of potential starting points for hit-to-lead campaigns. One such public set is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e6367dcb93d312ad1de98b74b72e5e
https://infoscience.epfl.ch/record/225923
https://infoscience.epfl.ch/record/225923