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of 6
pro vyhledávání: '"Matthew J. McGuffie"'
Autor:
Noor Radde, Genevieve A. Mortensen, Diya Bhat, Shireen Shah, Joseph J. Clements, Sean P. Leonard, Matthew J. McGuffie, Dennis M. Mishler, Jeffrey E. Barrick
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Engineered DNA will slow the growth of a host cell if it redirects limiting resources or otherwise interferes with homeostasis. Escape mutants that alleviate this burden can rapidly evolve and take over cell populations, making genetic engin
Externí odkaz:
https://doaj.org/article/d2a482698d444693acde04b2a15a0850
Autor:
Mackenzie M. Johnson, Adam J. Hockenberry, Matthew J. McGuffie, Luiz Carlos Vieira, Claus O. Wilke
Publikováno v:
bioRxiv
The most highly expressed genes in microbial genomes tend to use a limited set of synonymous codons, often referred to as “preferred codons.” The existence of preferred codons is commonly attributed to selection pressures on various aspects of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3692e350c2d3258b3cec11afea9c951a
https://doi.org/10.1101/2023.03.14.532645
https://doi.org/10.1101/2023.03.14.532645
Autor:
Matthew J McGuffie, Jeffrey E. Barrick
Publikováno v:
Nucleic Acids Research
Engineered plasmids are widely used in the biological sciences. Since many plasmids contain DNA sequences that have been reused and remixed by researchers for decades, annotation of their functional elements is often incomplete. Missing information a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5f2175c7c91b300febe80ab211597a
https://pubmed.ncbi.nlm.nih.gov/34019636
https://pubmed.ncbi.nlm.nih.gov/34019636
The classical and El Tor biotypes of Vibrio cholerae serogroup O1, the etiological agent of cholera, are responsible for the sixth and seventh (current) pandemics, respectively. A genomic island (GI), GI-24, previously identified in a classical bioty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec6d20e62cbe3bb01ebe39c6238f908
https://europepmc.org/articles/PMC4719448/
https://europepmc.org/articles/PMC4719448/
Autor:
John G. Younger, Joong Hwan Bahng, Matthew J. McGuffie, Nicholas A. Kotov, Emmanouil Glynos, J. Scott VanEpps, Jin Hong, Peter F. Green
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 12(1)
Despite a decade of engineering and process improvements, bacterial infection remains the primary threat to implanted medical devices. Zinc oxide nanoparticles (ZnO-NPs) have demonstrated antimicrobial properties. Their microbial selectivity, stabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a9037de74a32f78f3a6327345289e0
https://pubmed.ncbi.nlm.nih.gov/26515755
https://pubmed.ncbi.nlm.nih.gov/26515755
Autor:
Matthew J McGuffie, Jeffrey E Barrick
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0304164 (2024)
Engineered plasmids have been workhorses of recombinant DNA technology for nearly half a century. Plasmids are used to clone DNA sequences encoding new genetic parts and to reprogram cells by combining these parts in new ways. Historically, many gene
Externí odkaz:
https://doaj.org/article/d91b41bd21c34e1f82443d04436dde52