Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Matthew J. Loza"'
Autor:
Lydia J. Finney, Stefan Avey, Dexter Wiseman, Anthony Rowe, Matthew J. Loza, Patrick Branigan, Christopher S. Stevenson, Frédéric Baribaud, Jadwiga A. Wedzicha, Ioannis Pandis, Gavin C. Donaldson
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
Background Early and accurate identification of acute exacerbations of COPD may lead to earlier treatment and prevent hospital admission. Electronic diaries have been developed for symptom monitoring and accelerometers to monitor activity. However, i
Externí odkaz:
https://doaj.org/article/22593049a77b49ed87596d43e4afecae
Autor:
Jörg Menche, Emre Guney, Amitabh Sharma, Patrick J. Branigan, Matthew J. Loza, Frédéric Baribaud, Radu Dobrin, Albert-László Barabási
Publikováno v:
npj Systems Biology and Applications, Vol 3, Iss 1, Pp 1-10 (2017)
Molecular Medicine: Personalized expression profiles elucidate disease heterogeneity A comparison of gene expression profiles of different patients with the same disease reveals a combinatorial model for disease heterogeneity. A framework is develope
Externí odkaz:
https://doaj.org/article/edd0162ab2264d08b9f3fbaea8989ba2
Autor:
Kaiyin Fei, Peter C Taylor, Tom WJ Huizinga, Georg Schett, Matthew J Loza, Chetan S Karyekar, Bei Zhou, Jocelyn H Leu, Qingmin Wang, Keying Ma, Fowzia Ibrahim, Yuan Xiong, Sheng Gao, Sophia G Liva, Jafar Sadik B Shaik, Rohit A Panchakshari, Harman Dhatt, Ricardo Rojo Cella, Carolyn A Cuff
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Objectives To investigate the efficacy, safety, pharmacokinetics and pharmacodynamics of nipocalimab in participants with moderate to severe active rheumatoid arthritis (RA) and inadequate response or intolerance to ≥1 antitumour necrosis factor ag
Externí odkaz:
https://doaj.org/article/e8783e06cebd4815857f9ccfd2c182ba
Autor:
Georg Schett, Matthew J. Loza, Arumugam Palanichamy, Oliver FitzGerald, Christopher Ritchlin, Anne-Christine Bay-Jensen, Signe Holm Nielsen, Sheng Gao, Elizabeth C. Hsia, Alexa P. Kollmeier, Xie L. Xu, Frédéric Baribaud, Kristen Sweet
Publikováno v:
Rheumatology and Therapy. 9:1017-1030
Guselkumab, a novel interleukin-23p19 subunit monoclonal antibody, has been shown to effectively improve the diverse manifestations of active psoriatic arthritis (PsA) in two phase 3 trials (DISCOVER-1, DISCOVER-2). Serum concentrations of extracellu
Autor:
Philip E Silkoff, Dave Singh, J Mark FitzGerald, Andreas Eich, Andrea Ludwig-Sengpiel, Geoffrey C Chupp, Vibeke Backer, Celeste Porsbjerg, Pierre-Olivier Girodet, Mark T Dransfield, Frederic Baribaud, Vedrana S Susulic, Matthew J Loza
Publikováno v:
Biomarker Insights, Vol 12 (2017)
Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease, and development of novel therapeutics requires an understanding of pathophysiologic phenotypes. Objectives: The purpose of the Airways Disease Endotyping for Personal
Externí odkaz:
https://doaj.org/article/9367da2f9e8f433c9c01d12e25f3f173
Autor:
P. J. Sterk, John H. Riley, Thomas Sandström, Anna Selby, Laurie Pahus, C. Auffray, Ioannis Pandis, Julie Corfield, R. Djukanovic, K. Sun, Massimo Caruso, Jørgen Vestbo, Matthew J. Loza, Andrew J. Simpson, Dominic Burg, I.M. Adcock, S. Bates, Scott Wagers, Ana R. Sousa, J. Corfield, Ariane H. Wagener, René Lutter, Barbro Dahlén, Ratko Djukanovic, G. Praticò, I. Pandis, N. Mores, G. Hedlin, Navin Rao, I. Horváth, Alexander Mazein, B. De Meulder, Richard G. Knowles, John-Olof Thörngren, Wolfgang Seibold, P H Howarth, Victoria M. Goss, Cristina Gómez, Clare S. Murray, Paul Brinkman, Ildiko Horvath, Anthony D. Postle, M. Caruso, Martina Gahlemann, M. Puig Valls, F.K. Chung, P. Montuschi, Dominick E. Shaw, Kai Sun, Aruna T. Bansal, Fahad Alahmadi, Amphun Chaiboonchoe, Graham Roberts, Kian Fan Chung, Yike Guo, H. Ahmed, Thomas Geiser, Klaus Bønnelykke, M. Miralpeix, Simone Hashimoto, Diane Lefaudeux, S.S. Wagers, D. Erzen, B. Thornton, Florian Singer, Louise Fleming, Stephen J. Fowler, Neil Fitch, P. Bakke, Craig E. Wheelock, Nadja Hawwa Vissing, Tim Higenbottam, Jamie Matthews, F. Singer, S.E. Dahlén, Sarah Masefield, Roelinde Middelveld, Jens M. Hohlfeld, Anthony V. D'Amico, Paul Skipp, W.M.C. van Aalderen, Alan J. Knox, Sven-Erik Dahlén, Andrew Bush, A.T. Bansal, Pieter-Paul Hekking, Joost Brandsma, Stewart Bates, L.J. Fleming, Norbert Krug, N. Krug, Magnus Ericsson, J. Riley, P. Powel, Jacek Musiał, Amanda Roberts, Peter J. Sterk, Ian M. Adcock, Pascal Chanez, Cecile T.J. Holweg, F. Baribaud, Stelios Pavlidis, Veit J. Erpenbeck, Z. Weiszhart, C.E. Wheelock, Ralf Sigmund, James P.R. Schofield, Alexander Manta, Andrea Meiser, Susan J. Wilson, Jeanette Bigler, G. Roberts, M. van Geest, Hans Bisgaard, Urs Frey, Michael Boedigheimer, Per Bakke, Chris Compton, Enrica Bucchioni, Paolo Montuschi, David Myles, E.H.D. Bel, Anna James, Elena Formaggio, Anthony Rowe, Dominic E. Shaw, J. Haughney, P. Chanez, A.R. Sousa, S.J. Fowler, K. Fichtner, B. Dahlèn
Publikováno v:
U-BIOPRED Study Group 2021, ' Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort ', Chest . https://doi.org/10.1016/j.chest.2021.02.023
Alahmadi, Fahad H; Simpson, Andrew J; Gomez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Wheelock, Craig; Shaw, Dominic E; Fleming, Louise J; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R; Knowles, Richard; Bansal, Aruna T; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; ... (2021). Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort. Chest, 160(1), pp. 53-64. Elsevier 10.1016/j.chest.2021.02.023
Chest
Chest, 2021, 160 (1), pp.53-64. ⟨10.1016/j.chest.2021.02.023⟩
Chest, 160(1), 53-64. American College of Chest Physicians
Alahmadi, Fahad H; Simpson, Andrew J; Gomez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Wheelock, Craig; Shaw, Dominic E; Fleming, Louise J; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R; Knowles, Richard; Bansal, Aruna T; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; ... (2021). Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort. Chest, 160(1), pp. 53-64. Elsevier 10.1016/j.chest.2021.02.023
Chest
Chest, 2021, 160 (1), pp.53-64. ⟨10.1016/j.chest.2021.02.023⟩
Chest, 160(1), 53-64. American College of Chest Physicians
Background: Although estimates of suboptimal adherence to oral corticosteroids in asthma range from 30% to 50%, no ideal method for measurement exists; the impact of poor adherence in severe asthma is likely to be particularly high. Research Question
Autor:
Matthew J. Loza, Sunil Nagpal, Suzanne Cole, Renee M. Laird, Ashley Alcala, Navin L. Rao, Mark S. Riddle, Chad K. Porter
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.)REFERENCES. 74(11)
To identify a panel of serum biomarkers that could specifically identify imminent cases of rheumatoid arthritis (RA) before diagnosis.Serum samples were collected at 4 time points from active component US military personnel, including 157 anti-citrul
Autor:
Sven-Erik Dahlén, Kai Sun, Nazanin Zounemat Kermani, Stephany Sánchez-Ovando, Åsa M. Wheelock, John H. Riley, Craig E. Wheelock, Yike Guo, Stelios Pavlidis, Charles Auffray, Chih-Hsi Kuo, Peter J. Sterk, Bertrand De Meulder, Sharon Mumby, Kian Fan Chung, Peter A. B. Wark, Jodie L. Simpson, Jim Schofield, Paul Agapow, Ian M. Adcock, Matthew J. Loza, Katherine J. Baines, Kai Sen Tan, Ratko Djukanovic, Frédéric Baribaud, Mansoor Saqi, Ana R. Sousa
Publikováno v:
Allergy: European Journal of Allergy and Clinical Immunology, 76(1), 380-383. Wiley-Blackwell
Autor:
Georg Schett, Matthew J. Loza, Arumugam Palanichamy, Oliver FitzGerald, Christopher Ritchlin, Anne-Christine Bay-Jensen, Signe Holm Nielsen, Sheng Gao, Elizabeth C. Hsia, Alexa P. Kollmeier, Xie L. Xu, Frédéric Baribaud, Kristen Sweet
Publikováno v:
Rheumatology and Therapy. 9:1247-1248
Autor:
Peter J. Sterk, Nazanin Zounemat Kermani, Ian M. Adcock, Pascal Chanez, Florian Singer, Stewart Bates, Magnus Ericsson, John H. Riley, Jessica Lasky-Su, Romanas Chaleckis, Ildiko Horvath, Hector Gallart-Ayala, Stephen J. Fowler, Craig E. Wheelock, Norbert Krug, Henric Olsson, Stacey N. Reinke, Jacek Musiał, Peter H. Howarth, Matthew J. Loza, Kian Fan Chung, Barbro Dahlén, Thomas Geiser, Massimo Caruso, David I. Broadhurst, Cristina Gómez, Dominick E. Shaw, Johan Kolmert, Per Bakke, Angelica Tiotiu, Paolo Montuschi, Sile Hu, Ratko Djukanovic, Ana R. Sousa, Sven-Erik Dahlén, Frédéric Baribaud, James Scholfield, Shama Naz, Åsa M. Wheelock, Anders Lundqvist, Annelie F. Behndig, Marika Ström
Publikováno v:
European Respiratory Journal
Reinke, Stacey N; Naz, Shama; Chaleckis, Romanas; Gallart-Ayala, Hector; Kolmert, Johan; Kermani, Nazanin Z; Tiotiu, Angelica; Broadhurst, David I; Lundqvist, Anders; Olsson, Henric; Ström, Marika; Wheelock, Åsa M; Gómez, Cristina; Ericsson, Magnus; Sousa, Ana R; Riley, John H; Bates, Stewart; Scholfield, James; Loza, Matthew; Baribaud, Frédéric; ... (2022). Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study. European respiratory journal, 59(6) European Respiratory Society 10.1183/13993003.01733-2021
Reinke, S N, Naz, S, Chaleckis, R, Gallart-Ayala, H, Kolmert, J, Kermani, N Z, Tiotiu, A, Broadhurst, D I, Lundqvist, A, Olsson, H, Ström, M, Wheelock, Å M, Gómez, C, Ericsson, M, Sousa, A R, Riley, J H, Bates, S, Scholfield, J, Loza, M, Baribaud, F, Bakke, P S, Caruso, M, Chanez, P, Fowler, S J, Geiser, T, Howarth, P, Horváth, I, Krug, N, Montuschi, P, Behndig, A, Singer, F, Musial, J, Shaw, D E, Dahlén, B, Hu, S, Lasky-Su, J, Sterk, P J, Chung, K F, Djukanovic, R, Dahlén, S-E, Adcock, I M & Wheelock, C E 2021, ' Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study ', The European respiratory journal . https://doi.org/10.1183/13993003.01733-2021
European respiratory journal, 59(6):01733. European Respiratory Society
European Respiratory Journal, 2021, pp.2101733. ⟨10.1183/13993003.01733-2021⟩
Reinke, Stacey N; Naz, Shama; Chaleckis, Romanas; Gallart-Ayala, Hector; Kolmert, Johan; Kermani, Nazanin Z; Tiotiu, Angelica; Broadhurst, David I; Lundqvist, Anders; Olsson, Henric; Ström, Marika; Wheelock, Åsa M; Gómez, Cristina; Ericsson, Magnus; Sousa, Ana R; Riley, John H; Bates, Stewart; Scholfield, James; Loza, Matthew; Baribaud, Frédéric; ... (2022). Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study. European respiratory journal, 59(6) European Respiratory Society 10.1183/13993003.01733-2021
Reinke, S N, Naz, S, Chaleckis, R, Gallart-Ayala, H, Kolmert, J, Kermani, N Z, Tiotiu, A, Broadhurst, D I, Lundqvist, A, Olsson, H, Ström, M, Wheelock, Å M, Gómez, C, Ericsson, M, Sousa, A R, Riley, J H, Bates, S, Scholfield, J, Loza, M, Baribaud, F, Bakke, P S, Caruso, M, Chanez, P, Fowler, S J, Geiser, T, Howarth, P, Horváth, I, Krug, N, Montuschi, P, Behndig, A, Singer, F, Musial, J, Shaw, D E, Dahlén, B, Hu, S, Lasky-Su, J, Sterk, P J, Chung, K F, Djukanovic, R, Dahlén, S-E, Adcock, I M & Wheelock, C E 2021, ' Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study ', The European respiratory journal . https://doi.org/10.1183/13993003.01733-2021
European respiratory journal, 59(6):01733. European Respiratory Society
European Respiratory Journal, 2021, pp.2101733. ⟨10.1183/13993003.01733-2021⟩
IntroductionAsthma is a heterogeneous disease with poorly defined phenotypes. Patients with severe asthma often receive multiple treatments including oral corticosteroids (OCS). Treatment may modify the observed metabotype, rendering it challenging t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e44649ee35b8f7c945ee381b8be1f1
https://hdl.handle.net/11250/3025378
https://hdl.handle.net/11250/3025378