Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Matthew J. Jenny"'
Autor:
Mark E Hahn, Andrew G McArthur, Sibel I Karchner, Diana G Franks, Matthew J Jenny, Alicia R Timme-Laragy, John J Stegeman, Bruce R Woodin, Michael J Cipriano, Elwood Linney
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113158 (2014)
Oxidative stress is an important mechanism of chemical toxicity, contributing to teratogenesis and to cardiovascular and neurodegenerative diseases. Developing animals may be especially sensitive to chemicals causing oxidative stress. The development
Externí odkaz:
https://doaj.org/article/9f04281701d54484a502ec62aef1c01a
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 191:138-151
Heme oxygenase 1 (HMOX1) degrades heme into biliverdin, which is subsequently converted to bilirubin by biliverdin reductase (BVRa or BVRb) in a manner analogous to the classic anti-oxidant glutathione-recycling pathway. To gain a better understandin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ba2136acdaf0bddf6dbde66493d0ba
https://doi.org/10.1016/j.cbpc.2016.10.006
https://doi.org/10.1016/j.cbpc.2016.10.006
Phylogenetic Analysis of Molluscan Metallothioneins: Evolutionary Insight from Crassostrea virginica
Publikováno v:
Journal of Molecular Evolution. 83:110-125
Mechanisms by which organisms genetically adapt to environmental conditions are of fundamental importance to studies of evolutionary biology and environmental physiology. Natural selection acts on existing genetic variation leading to adaptation thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d41c49deaffa4f11a92086737e003db
https://doi.org/10.1007/s00239-016-9758-4
https://doi.org/10.1007/s00239-016-9758-4
Autor:
Robert H. Findlay, Kirsten Diggins, John M. Powers, William C. Walton, Charles E. Cunningham, Mark Pinkerton, Matthew J. Jenny, Daniel M. Crane, Samantha L. Payton, Danielle T. Porter, Jeffrey Tapley, Britton O'Shields
Publikováno v:
Marine Environmental Research. 120:166-181
Estuarine organisms were impacted by the Deepwater Horizon oil spill which released ∼5 million barrels of crude oil into the Gulf of Mexico in the spring and summer of 2010. Crassostrea virginica, the American oyster, is a keystone species in these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082eb61bb4201a99fbf22119c18fc45d
https://doi.org/10.1016/j.marenvres.2016.08.006
https://doi.org/10.1016/j.marenvres.2016.08.006
Publikováno v:
Marine environmental research. 134
Estuarine organisms are subjected to combinations of anthropogenic and natural stressors, which together can reduce an organisms' ability to respond to either stress or can potentiate or synergize the cellular impacts for individual stressors. Nemato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cb10335cb94774c4fdce3108f8ea7a
https://pubmed.ncbi.nlm.nih.gov/29336831
https://pubmed.ncbi.nlm.nih.gov/29336831
Autor:
Jeffrey Tapley, Martin Kamper, Andrew Holowiecki, Andrew G. McArthur, Matthew J. Jenny, Britton O'Shields
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843(9):1818-1833
The metal responsive element-binding transcription factor-1 (MTF-1) responds to changes in cellular zinc levels caused by zinc exposure or disruption of endogenous zinc homeostasis by heavy metals or oxygen-related stress. Here we report the function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d787dbebe6b92f5fc8b7bfa8f6db18eb
Publikováno v:
Toxicology and applied pharmacology. 311
While heme is an important cofactor for numerous proteins, it is highly toxic in its unbound form and can perpetuate the formation of reactive oxygen species. Heme oxygenase enzymes (HMOX1 and HMOX2) degrade heme into biliverdin and carbon monoxide,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f90f06e0772206c34ffcec4b88499ec
https://pubmed.ncbi.nlm.nih.gov/30031761
https://pubmed.ncbi.nlm.nih.gov/30031761
Publikováno v:
Journal of Experimental Biology.
Freshwater mussels, aquatic keystone species, are in global decline. Long life spans, sedentary lifestyles, and unique reproductive strategies involving obligate parasitic stages make unionid freshwater mussels particularly sensitive to environmental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44d0c21cc79695f64187c438a647083
https://doi.org/10.1242/jeb.140129
https://doi.org/10.1242/jeb.140129
Autor:
Rachel C. Harbeitner, Jared V. Goldstone, Sibel I. Karchner, Alicia R. Timme-Laragy, Matthew J. Jenny, Mark E. Hahn, Andrew G. McArthur, Diana G. Franks
Publikováno v:
Journal of Biological Chemistry. 287:4609-4627
NF-E2-related factor 2 (NRF2; also called NFE2L2) and related NRF family members regulate antioxidant defenses by activating gene expression via antioxidant response elements (AREs), but their roles in embryonic development are not well understood. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b67f21109365d09a7bf5b24b7d878c
https://doi.org/10.1074/jbc.m111.260125
https://doi.org/10.1074/jbc.m111.260125
Publikováno v:
Toxicology and Applied Pharmacology. 356:98
While heme is an important cofactor for numerous proteins, it is highly toxic in its unbound form and can perpetuate the formation of reactive oxygen species. Heme oxygenase enzymes (HMOX1 and HMOX2) degrade heme into biliverdin and carbon monoxide,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196e58cc1c5d8b043e10b57090fda2fc
https://doi.org/10.1016/j.taap.2018.07.021
https://doi.org/10.1016/j.taap.2018.07.021