Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Matthew J. Gamble"'
Autor:
Penelope D. Ruiz, Matthew J. Gamble
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The histone variant macroH2A1 localizes to two functionally distinct chromatin subtypes marked by either H3K27me3 or H2B acetylations. Here the authors identify the features of macroH2A1 required for its recruitment to H2B-acetylated chromatin and id
Externí odkaz:
https://doaj.org/article/115539ae4c2c459d9edc92e220d1745a
Autor:
Maxim I Maron, Alyssa D Casill, Varun Gupta, Jacob S Roth, Simone Sidoli, Charles C Query, Matthew J Gamble, David Shechter
Publikováno v:
eLife, Vol 11 (2022)
Protein arginine methyltransferases (PRMTs) are required for the regulation of RNA processing factors. Type I PRMT enzymes catalyze mono- and asymmetric dimethylation; Type II enzymes catalyze mono- and symmetric dimethylation. To understand the spec
Externí odkaz:
https://doaj.org/article/45b87284ee8349d28110b43dc16d75b2
Autor:
Gregory A, Hamilton, Matthew J, Gamble
Publikováno v:
Nature structuralmolecular biology. 28(12)
Autor:
Matthew J. Gamble, Varun Gupta, Maxim I. Maron, David Shechter, Simone Sidoli, Alyssa D. Casill, Charles C. Query
Protein arginine methyltransferases (PRMTs) are required for the regulation of RNA processing factors. Type I enzymes catalyze mono- and asymmetric dimethylation; Type II enzymes catalyze mono- and symmetric dimethylation. To understand the specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cca87d39fa3b17cc7158f5adc9946cfb
https://doi.org/10.1101/2021.08.20.457069
https://doi.org/10.1101/2021.08.20.457069
Autor:
Maxim I Maron, Alyssa D Casill, Varun Gupta, Jacob S Roth, Simone Sidoli, Charles C Query, Matthew J Gamble, David Shechter
Publikováno v:
eLife
eLife, Vol 11 (2022)
eLife, Vol 11 (2022)
Protein arginine methyltransferases (PRMTs) are required for the regulation of RNA processing factors. Type I PRMT enzymes catalyze mono- and asymmetric dimethylation; Type II enzymes catalyze mono- and symmetric dimethylation. To understand the spec
Autor:
Kenny Ye, Charles C. Query, Brian Kosmyna, Matthew J. Gamble, Alyssa D. Casill, Adam J. Haimowitz
SummaryThe organization of the genome in three-dimensional space has been shown to play an important role in gene expression. Specifically, facets of genomic interaction such as topologically associated domains (TADs) have been shown to regulate tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b6af1203a09ed703c7d18b878d7ca37
https://doi.org/10.1101/2021.01.28.428713
https://doi.org/10.1101/2021.01.28.428713
Autor:
Hongshan Chen, Emmanuel S. Burgos, Charles C. Query, Varun Gupta, David Shechter, Matthew J. Gamble, Alyssa D. Casill, Maxim I. Maron, Brian Kosmyna
Protein arginine methyltransferases (PRMTs) methylate histones, splicing factors, and many other nuclear proteins. Type I enzymes (PRMT1-4,6,8) catalyze mono- (Rme1/MMA) and asymmetric (Rme2a/ADMA) dimethylation; Type II enzymes (PRMT5,9) catalyze mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea5ac62271548bdb45d0a395e6d75f9
https://doi.org/10.1101/2020.11.18.389288
https://doi.org/10.1101/2020.11.18.389288
Autor:
Sean E. Healton, Yali Dou, Hugo D. Pinto, Ulrich Steidl, Gregory A. Hamilton, Matthew J. Gamble, Kalina Swist-Rosowska, Nicholas Shukeir, Arthur I. Skoultchi, Laxmi N. Mishra, Thomas Jenuwein, Justin C. Wheat
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Nearly 50% of mouse and human genomes are composed of repetitive sequences. Transcription of these sequences is tightly controlled during development to prevent genomic instability, inappropriate gene activation and other maladaptive processes. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260e9b8f9bbb31d023d7611c28577f9a
https://hdl.handle.net/21.11116/0000-0007-DA73-221.11116/0000-0007-DA75-0
https://hdl.handle.net/21.11116/0000-0007-DA73-221.11116/0000-0007-DA75-0
Publikováno v:
Molecular and Cellular Biology
Through its ability to bind the ends of poly(ADP-ribose) (PAR) chains, the function of the histone variant macroH2A1.1, including its ability to regulate transcription, is coupled to PAR polymerases (PARPs). PARP1 also has a major role in DNA damage