Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Matthew J. Fogarty"'
Publikováno v:
Physiological Reports, Vol 12, Iss 16, Pp n/a-n/a (2024)
Abstract Aging is associated with cardiac contractile abnormalities, but the etiology of these contractile deficits is unclear. We hypothesized that cardiac contractile and regulatory protein expression is altered during aging. To investigate this po
Externí odkaz:
https://doaj.org/article/f577a9b7cdf84a6c8ed5051c85411fc2
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
In amyotrophic lateral sclerosis (ALS) postmortem tissue and the SOD1 mouse model at mid-disease, death of hypoglossal motor neurons (XII MNs) is evident. These XII MNs innervate the intrinsic and extrinsic tongue muscles, and despite their importanc
Externí odkaz:
https://doaj.org/article/200989ceacc844b09f2bd1a936ff92f2
Autor:
Matthew J. Fogarty
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
IntroductionMotor neurons (MNs) within the nucleus ambiguus innervate the skeletal muscles of the larynx, pharynx, and oesophagus. These muscles are activated during vocalisation and swallowing and must be coordinated with several respiratory and oth
Externí odkaz:
https://doaj.org/article/41994761492f4e409a351ab81f9449a3
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Introduction: Vasodilatation in response to NO is a fundamental response of the vasculature, and during aging, the vasculature is characterized by an increase in stiffness and decrease in sensitivity to NO mediated vasodilatation. Vascular tone is re
Externí odkaz:
https://doaj.org/article/15a795b98918469b9b56d5e82132cc86
Publikováno v:
Physiological Reports, Vol 12, Iss 5, Pp n/a-n/a (2024)
Abstract Cervical spinal cord injury impacts ventilatory and non‐ventilatory functions of the diaphragm muscle (DIAm) and contributes to clinical morbidity and mortality in the afflicted population. Periodically, integrated brainstem neural circuit
Externí odkaz:
https://doaj.org/article/9d3dec18a307486880a1c75185179145
Autor:
Matthew J. Fogarty, Gary C. Sieck
Publikováno v:
Physiological Reports, Vol 11, Iss 2, Pp n/a-n/a (2023)
Abstract Diaphragm muscle (DIAm) motor units comprise a phrenic motor neuron (PhMN), the phrenic nerve and the muscle fibers innervated, with the size of PhMNs and axons characteristic of motor unit type. Smaller PhMNs and their axons comprise slow (
Externí odkaz:
https://doaj.org/article/b918a001dcbf404c8508c3f37189c285
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The neuromuscular junction (NMJ) mediates neural control of skeletal muscle fibers. Neurotrophic signaling, specifically brain derived neurotrophic factor (BDNF) acting through its high-affinity tropomyosin related kinase B (TrkB) receptor is known t
Externí odkaz:
https://doaj.org/article/e32bda53bc914dac943bbdf4645eb6ac
Autor:
Matthew J. Fogarty
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 6962 (2023)
During development, GABA and glycine play major trophic and synaptic roles in the establishment of the neuromotor system. In this review, we summarise the formation, function and maturation of GABAergic and glycinergic synapses within neuromotor circ
Externí odkaz:
https://doaj.org/article/7ec2da9994eb4e47b1120c44cf184ae1
Autor:
Stuart B. Mazzone, Seung-Kwon Yang, Jennifer A. Keller, Juste Simanauskaite, Jaisy Arikkatt, Matthew J. Fogarty, Aung Aung Kywe Moe, Chen Chen, Matthew W. Trewella, Luyi Tian, Matthew E. Ritchie, Brendan Y. Chua, Simon Phipps, Kirsty R. Short, Alice E. McGovern
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Vagal sensory neurons contribute to the symptoms and pathogenesis of inflammatory pulmonary diseases through processes that involve changes to their morphological and functional characteristics. The alarmin high mobility group box-1 (HMGB1) is an ear
Externí odkaz:
https://doaj.org/article/290a350339b04b75b5ded892b012d568
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Sarcopenia is characterized by muscle fiber atrophy and weakness, which may be associated with mitochondrial fragmentation and dysfunction. Mitochondrial remodeling and biogenesis in muscle fibers occurs in response to exercise and increased muscle a
Externí odkaz:
https://doaj.org/article/e9d06e0ee06e4c6a8a12a69633dd4d87