Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Matthew J. Bellizzi"'
Autor:
Jennetta W. Hammond, Caroline Ware, Yuanhao Li, Matthew J. Bellizzi, Priyanka Saminathan, Shaopeiwen Luo, Harris A. Gelbard, Stefanie A. Ma, Herman Li, Wen Q. Qiu
Publikováno v:
Brain Behav Immun
Multiple sclerosis (MS) is an inflammatory, neurodegenerative disease of the CNS characterized by both grey and white matter injury. Microglial activation and a reduction in synaptic density are key features of grey matter pathology that can be model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94478783e1546debab03f9a9c8cda78
https://doi.org/10.1016/j.bbi.2020.03.004
https://doi.org/10.1016/j.bbi.2020.03.004
Autor:
Jennetta W. Hammond, Matthew J. Bellizzi, Caroline Ware, Wen Q. Qiu, Priyanka Saminathan, Herman Li, Shaopeiwen Luo, Yuanhao Li, Harris A. Gelbard
Multiple sclerosis (MS) is an inflammatory, neurodegenerative disease of the CNS characterized by both grey and white matter injury. Microglial activation and a reduction in synaptic density are key features of grey matter pathology that can be model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e271ee4b2f43787a380aa651ae177b
Autor:
Jennetta W. Hammond, Mary A. Gantz Marker, Daniel F. Marker, Herman Li, Harris A. Gelbard, Matthew J. Bellizzi, Robert S. Freeman
Publikováno v:
eNeuro
Treatments to stop gray matter degeneration are needed to prevent progressive disability in multiple sclerosis (MS). We tested whether inhibiting mixed-lineage kinases (MLKs), which can drive inflammatory microglial activation and neuronal degenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd83aaee686bfbf00b8d65d6e9f6ec4
https://pubmed.ncbi.nlm.nih.gov/30627663
https://pubmed.ncbi.nlm.nih.gov/30627663
Autor:
Matthew J. Bellizzi, Shao-Ming Lu, Will Greaves-Tunnell, Wen Q. Qiu, Jeffrey M. Chamberlain, Harris A. Gelbard, Jennetta W. Hammond, Daniel F. Marker
Publikováno v:
Glia. 66(12)
Microglial activation, increased proinflammatory cytokine production, and a reduction in synaptic density are key pathological features associated with HIV-associated neurocognitive disorders (HAND). Even with combination antiretroviral therapy (cART
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82fab00a94c4aa404338447c0f10b4d9
https://pubmed.ncbi.nlm.nih.gov/30325063
https://pubmed.ncbi.nlm.nih.gov/30325063
Gray matter degeneration contributes to progressive disability in multiple sclerosis (MS) and can occur out of proportion to measures of white matter disease. Although white matter pathology, including demyelination and axon injury, can lead to secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431d6eee5a178656d0c5705ef028d8b0
https://europepmc.org/articles/PMC4728729/
https://europepmc.org/articles/PMC4728729/
Publikováno v:
Journal of Clinical Investigation. 115:3185-3192
Neurologic impairment in HIV-1–associated dementia (HAD) and other neuroinflammatory diseases correlates with injury to dendrites and synapses, but how such injury occurs is not known. We hypothesized that neuroinflammation makes dendrites suscepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d02206798fe14d1683d6ceadf6a0788
https://doi.org/10.1172/jci25444
https://doi.org/10.1172/jci25444
Publikováno v:
Journal of Neurovirology
Tumor necrosis factor-alpha (TNF-alpha) is pleiotropic mediator of a diverse array of physiological and neurological functions, including both normal regulatory functions and immune responses to infectious agents. Its role in the nervous system is pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f393163af1d636c0f96982c3849dbbc1
https://doi.org/10.1080/13550280290101021
https://doi.org/10.1080/13550280290101021
Publikováno v:
Journal of Applied Physiology. 89:1991-1999
We twice tested the hypothesis that top running speeds are determined by the amount of force applied to the ground rather than how rapidly limbs are repositioned in the air. First, we compared the mechanics of 33 subjects of different sprinting abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbeef75d8e2d54ae2d2531657125103
https://doi.org/10.1152/jappl.2000.89.5.1991
https://doi.org/10.1152/jappl.2000.89.5.1991
Autor:
Matthew J. Bellizzi, Harris A. Gelbard
Diminution in synaptic function and loss of normal synaptic architecture are likely to be the biologically relevant substrate for neurologic deficits in patients with HIV-1-associated dementia (HAD) and patients suffering from the prionoses. Because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::012e6af3ee66aba42bbbff9d2100a40b
https://doi.org/10.1016/b978-008045046-9.00503-9
https://doi.org/10.1016/b978-008045046-9.00503-9
Publikováno v:
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 1(1)
Loss of synaptic integrity and function appears to underlie neurologic deficits in patients with HIV-1-associated dementia (HAD) and other chronic neurodegenerative diseases. Because synaptic injury often long precedes neuronal death and surviving ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4860b2826afb628cdb734c54a4129bd8
https://pubmed.ncbi.nlm.nih.gov/18040788
https://pubmed.ncbi.nlm.nih.gov/18040788