Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Matthew J. Beam"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 10, Pp 814-823 (2014)
Defects in telomere maintenance can result in telomere fusions that likely play a causative role in carcinogenesis by promoting genomic instability. However, this proposition remains to be fully understood in human colon carcinogenesis. In the presen
Externí odkaz:
https://doaj.org/article/6897cf07e8df4c4e8a567c4ce7d231d2
Autor:
Nazmul Huda, David Gilley, Hiromi Tanaka, Matthew J. Beam, Satoshi Abe, Li Ren Tu, Brenda R. Grimes
Publikováno v:
Proceedings of the National Academy of Sciences. 109:14098-14103
Several lines of evidence suggest that defects in telomere maintenance play a significant role in the initiation of genomic instability during carcinogenesis. Although the general concept of defective telomere maintenance initiating genomic instabili