Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Matthew J Wood"'
Publikováno v:
Medicine Access @ Point of Care, Vol 5 (2021)
Objective: Amid COVID-19 disruptions, e-therapy has become even more essential and has rapidly expanded across statutory, private and third sectors to meet growing demands for digital mental health support. A challenge in digital therapeutic care is
Externí odkaz:
https://doaj.org/article/023f7bde0c5549c385fe7dee8ddeda97
Autor:
Alison M Blain, Elizabeth Greally, Graham McClorey, Raquel Manzano, Corinne A Betts, Caroline Godfrey, Liz O'Donovan, Thibault Coursindel, Mike J Gait, Matthew J Wood, Guy A MacGowan, Volker W Straub
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198897 (2018)
Cardiac failure is a major cause of mortality in patients with Duchenne muscular dystrophy (DMD). Antisense-mediated exon skipping has the ability to correct out-of-frame mutations in DMD to produce truncated but functional dystrophin. Traditional an
Externí odkaz:
https://doaj.org/article/3ba329284b914067ab2dc83073aab5b6
Autor:
Tamás Baranyai, Kata Herczeg, Zsófia Onódi, István Voszka, Károly Módos, Nikolett Marton, György Nagy, Imre Mäger, Matthew J Wood, Samir El Andaloussi, Zoltán Pálinkás, Vikas Kumar, Péter Nagy, Ágnes Kittel, Edit Irén Buzás, Péter Ferdinandy, Zoltán Giricz
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145686 (2015)
Exosomes are emerging targets for biomedical research. However, suitable methods for the isolation of blood plasma-derived exosomes without impurities have not yet been described.Therefore, we investigated the efficiency and purity of exosomes isolat
Externí odkaz:
https://doaj.org/article/477316d3c7364d13be139dc2352c586c
Autor:
Irene González-Martínez, Estefanía Cerro-Herreros, Nerea Moreno, Andrea García-Rey, Jorge Espinosa-Espinosa, Marc Carrascosa-Sàez, Diego Piqueras-Losilla, Andrey Arzumanov, David Seoane-Miraz, Yahya Jad, Richard Raz, Matthew J. Wood, Miguel A. Varela, Beatriz Llamusí, Rubén Artero
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102024- (2023)
Myotonic dystrophy type 1 (DM1) is a rare neuromuscular disease caused by a CTG repeat expansion in the DMPK gene that generates toxic RNA with a myriad of downstream alterations in RNA metabolism. A key consequence is the sequestration of alternativ
Externí odkaz:
https://doaj.org/article/eab157fbac924adb8443e448d8ae4b14
Autor:
Alia M. Obeidat, Matthew J. Wood, Natalie S. Adamczyk, Shingo Ishihara, Jun Li, Lai Wang, Dongjun Ren, David A. Bennett, Richard J. Miller, Anne-Marie Malfait, Rachel E. Miller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Non-opioid targets are needed for addressing osteoarthritis pain, which is mechanical in nature and associated with daily activities such as walking and climbing stairs. Piezo2 has been implicated in the development of mechanical pain, but t
Externí odkaz:
https://doaj.org/article/222c434eeda94f0a8702d3c3debb578f
Autor:
Robin Vroman, Rahel S. Hunter, Matthew J. Wood, Olivia C. Davis, Zoë Malfait, Dale S. George, Dongjun Ren, Diana Tavares-Ferreira, Theodore J. Price, Richard J. Miller, Anne-Marie Malfait, Fransiska Malfait, Rachel E. Miller, Delfien Syx
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The extracellular matrix (ECM) is a dynamic structure of molecules that can be divided into six different categories and are collectively called the matrisome. The ECM plays pivotal roles in physiological processes in many tissues, including the nerv
Externí odkaz:
https://doaj.org/article/87f54fe5bb164f508a368543eff00691
Autor:
Jamuna Selvakumaran, Simona Ursu, Melissa Bowerman, Ngoc Lu-Nguyen, Matthew J. Wood, Alberto Malerba, Rafael J. Yáñez-Muñoz
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2700 (2023)
The blood–brain barrier (BBB) is the specialised microvasculature system that shields the central nervous system (CNS) from potentially toxic agents. Attempts to develop therapeutic agents targeting the CNS have been hindered by the lack of predict
Externí odkaz:
https://doaj.org/article/14867b7d6d744afa821bb2668320729c
Autor:
Fiona Cooke, Mary Neal, Matthew J. Wood, I. Jolanda M. de Vries, Amy E. Anderson, Julie Diboll, Arthur G. Pratt, James Stanway, Ioana Nicorescu, Nicholas Moyse, Dawn Hiles, David Caulfield, Anne M. Dickinson, Andrew M. Blamire, Pete Thelwall, John D. Isaacs, Catharien M. U. Hilkens
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tolerogenic dendritic cell (tolDC) therapies aim to restore self-tolerance in patients suffering from autoimmune diseases. Phase 1 clinical trials with tolDC have shown the feasibility and safety of this approach, but have also highlighted a lack of
Externí odkaz:
https://doaj.org/article/47a487e2cf1e43fca48e6bf3f7d8fb41
Autor:
Victoria L. Hartley, Arwa M. Qaqish, Matthew J. Wood, Brian T. Studnicka, Kazuhiro Iwai, Ta-Chiang Liu, Donna A. MacDuff
HOIL1-deficient patients experience chronic intestinal inflammation and diarrhea as well as increased susceptibility to certain bacterial infections. HOIL1 is a component of the linear ubiquitin chain assembly complex (LUBAC) that regulates immune si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc91cc700d86800450c6c0b390e6c813
https://doi.org/10.1101/2023.05.22.541746
https://doi.org/10.1101/2023.05.22.541746
Publikováno v:
Clin Geriatr Med
Chronic pain is a substantial personal and societal burden worldwide. Osteoarthritis (OA) is one of the leading causes of chronic pain and is increasing in prevalence in accordance with a global aging population. In addition to affecting patients' ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00531234b0c5d1825759190dd7d5de3d
https://doi.org/10.1016/j.cger.2021.11.013
https://doi.org/10.1016/j.cger.2021.11.013