Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Matthew J Smalley"'
Autor:
Jason S. Williams, Adam T. Higgins, Katie J. Stott, Carly Thomas, Lydia Farrell, Cleo S. Bonnet, Severina Peneva, Anna V. Derrick, Trevor Hay, Tianqi Wang, Claire Morgan, Sarah Dwyer, Joshua D’Ambrogio, Catherine Hogan, Matthew J. Smalley, Lee Parry, Paul Dyson
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Background Bacterial cancer therapy was first trialled in patients at the end of the nineteenth century. More recently, tumour-targeting bacteria have been harnessed to deliver plasmid-expressed therapeutic interfering RNA to a range of soli
Externí odkaz:
https://doaj.org/article/8c3e84c87887414daa7d1ff63ddb1679
Autor:
Juan Manuel Iglesias, Claire J Cairney, Roderick K Ferrier, Laura McDonald, Kelly Soady, Howard Kendrick, Marie-Anne Pringle, Reginald O Morgan, Finian Martin, Matthew J Smalley, Karen Blyth, Torsten Stein
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119718 (2015)
We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA8 mRNA is expressed in low-pro
Externí odkaz:
https://doaj.org/article/bf01c0a98e5948528c6de9937ed9455a
Autor:
Michael Cowley, Alastair S Garfield, Marta Madon-Simon, Marika Charalambous, Richard W Clarkson, Matthew J Smalley, Howard Kendrick, Anthony R Isles, Aled J Parry, Sara Carney, Rebecca J Oakey, Lora K Heisler, Kim Moorwood, Jason B Wolf, Andrew Ward
Publikováno v:
PLoS Biology, Vol 12, Iss 2, p e1001799 (2014)
Developmental programming links growth in early life with health status in adulthood. Although environmental factors such as maternal diet can influence the growth and adult health status of offspring, the genetic influences on this process are poorl
Externí odkaz:
https://doaj.org/article/3f393f133352438498efee9639902e4d
Autor:
Dan G. O’Neill, Grace L. Edmunds, Jade Urquhart-Gilmore, David B. Church, Lynda Rutherford, Matthew J. Smalley, Dave C. Brodbelt
Publikováno v:
Canine Medicine and Genetics, Vol 10, Iss 1, Pp 1-17 (2023)
Abstract Background Osteosarcoma is a malignant bone neoplasia that has high welfare consequences for affected dogs. Awareness of breed and canine conformational risk factors for osteosarcoma can assist with earlier diagnosis and improved clinical ma
Externí odkaz:
https://doaj.org/article/ee3bcf2179c64d919995ec59d8bca5ef
Autor:
Giusy Tornillo, Lauren Warrington, Howard Kendrick, Adam T. Higgins, Trevor Hay, Sam Beck, Matthew J. Smalley
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/48df8545687f444d83f560c04bbf5e5a
Autor:
Grace L. Edmunds, Matthew J. Smalley, Sam Beck, Rachel J. Errington, Sara Gould, Helen Winter, Dave C. Brodbelt, Dan G. O’Neill
Publikováno v:
Canine Medicine and Genetics, Vol 8, Iss 1, Pp 1-22 (2021)
Abstract Background Osteosarcoma is an aggressive and painful bone neoplasm in dogs. Previous studies have reported epidemiological associations suggesting that large body mass, long bone length and the genetics of certain breeds including the Rottwe
Externí odkaz:
https://doaj.org/article/e02e3a72f63a4f4d87436c1d159aaa11
Autor:
Boris Shorning, Neil Trent, David F. Griffiths, Thomas Worzfeld, Stefan Offermanns, Matthew J. Smalley, Magali Williamson
Publikováno v:
Cancer Research Communications. 3:444-458
Metastatic prostate cancer is essentially incurable and is a leading cause of cancer-related morbidity and mortality in men, yet the underlying molecular mechanisms are poorly understood. Plexins are transmembrane receptors for semaphorins with diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f45007b70fe703f73527f0d0ce86103b
https://doi.org/10.1158/2767-9764.crc-22-0480
https://doi.org/10.1158/2767-9764.crc-22-0480
Autor:
Liliana D. Ordonez, Lorenzo Melchor, Kirsty R. Greenow, Howard Kendrick, Giusy Tornillo, James Bradford, Peter Giles, Matthew J. Smalley
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 5 (2021)
Understanding the mechanisms underlying tumour heterogeneity is key to the development of treatments that can target specific tumour subtypes. We have previously targeted CRE recombinase-dependent conditional deletion of the tumour suppressor genes B
Externí odkaz:
https://doaj.org/article/373e2c15d39b4e32aea52cbb5bd3026f
Autor:
Kelly Chiang, Agnieszka E. Zielinska, Abeer M. Shaaban, Maria Pilar Sanchez-Bailon, James Jarrold, Thomas L. Clarke, Jingxian Zhang, Adele Francis, Louise J. Jones, Sally Smith, Olena Barbash, Ernesto Guccione, Gillian Farnie, Matthew J. Smalley, Clare C. Davies
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3498-3513 (2017)
Summary: Breast cancer progression, treatment resistance, and relapse are thought to originate from a small population of tumor cells, breast cancer stem cells (BCSCs). Identification of factors critical for BCSC function is therefore vital for the d
Externí odkaz:
https://doaj.org/article/c87094c1b9fa49f294c1e88bb72d1739
Autor:
Danielle Varney, Dan O'Neill, Maeve O'Neill, David Church, Anneliese Stell, Sam Beck, Matthew J. Smalley, David Brodbelt
Publikováno v:
Veterinary Record.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5845e6a45494178637a61cf275e1083c
https://doi.org/10.1002/vetr.3054
https://doi.org/10.1002/vetr.3054