Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Matthew J Piggott"'
Autor:
Thomas S Anderson, Graham A Rance, Long Jiang, Matthew J Piggott, Elinor J Field, Guillaume P Chanoit
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207471 (2018)
OBJECTIVE:To (1) characterise the chemical and ultra-structural composition of ameroid constrictors, at a native state and during in vitro expansion and (2) determine the presence of irritant compounds at the surface or within the bulk of the constri
Externí odkaz:
https://doaj.org/article/192ddc0fc09c477fbd190372f72d9e88
Autor:
Caitlin M. Tilsed, M. Lizeth Orozco Morales, Rachael M. Zemek, Brianna A. Gordon, Matthew J. Piggott, Anna K. Nowak, Scott A. Fisher, Richard A. Lake, W. Joost Lesterhuis
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Chemotherapy is included in treatment regimens for many solid cancers, but when administered as a single agent it is rarely curative. The addition of immune checkpoint therapy to standard chemotherapy regimens has improved respons
Externí odkaz:
https://doaj.org/article/604f2ab58dbd40a8bc1286fd39a00ca8
Autor:
Philippe Huot, Tom H Johnston, Michael N Gandy, M Gabriela Reyes, Susan H Fox, Matthew J Piggott, Jonathan M Brotchie
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45587 (2012)
The wearing-OFF phenomenon is a common motor complication of chronic L-3,4-dihydroxyphenylalanine (L-DOPA) therapy for Parkinson's disease. We recently described the discovery of UWA-101, a dual serotonin (SERT) and dopamine (DAT) transporter inhibit
Externí odkaz:
https://doaj.org/article/b378e06c8da84467a2309cddd24be4f5
Autor:
M. Lizeth Orozco Morales, Catherine A. Rinaldi, Emma de Jong, Sally M. Lansley, Joel P.A. Gummer, Bence Olasz, Shabarinath Nambiar, Danika E. Hope, Thomas H. Casey, Y. C. Gary Lee, Connull Leslie, Gareth Nealon, David M. Shackleford, Andrew K. Powell, Marina Grimaldi, Patrick Balaguer, Rachael M. Zemek, Anthony Bosco, Matthew J. Piggott, Alice Vrielink, Richard A. Lake, W. Joost Lesterhuis
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103571- (2022)
Summary: Mesothelioma is a cancer that typically originates in the pleura of the lungs. It rapidly invades the surrounding tissues, causing pain and shortness of breath. We compared cell lines injected either subcutaneously or intrapleurally and foun
Externí odkaz:
https://doaj.org/article/6d9c2a0cd5324c82ad3d7f092e5dbba3
Publikováno v:
Journal of Natural Products. 86:550-556
Autor:
David Jago, Amelia R. Langley, Samantha G. Eaves, Mark C. Walkey, Thea Pulbrook, Stephen A. Moggach, Matthew J. Piggott, Paul J. Low, George A. Koutsantonis
Publikováno v:
Dalton Transactions. 52:185-200
Whilst inert to electrochemical stimulus, acid-induced ring-opening of an ethynyl spiropyran ligand in Ru complexes proceeds to form the protonated merocyanine, that can be switched from the Z- to E-form by UV light.
Autor:
Marco R. Buccini, Shi Yuan Jeow, Glenn A. Pullella, Han Chern Loh, Brian W. Skelton, Stephen A. Moggach, Matthew J. Piggott
Publikováno v:
Arkivoc. 2022:154-169
Autor:
Gavin R. Flematti, Gemma F. Turner, Matthew J. Piggott, George A. Koutsantonis, Alexandre N. Sobolev, Max Roemer, Stephen A. Moggach, Claire L. Hobday, Gareth L. Nealon, Duncan A. Wild, Angus A. Gillespie
Publikováno v:
Crystal Growth & Design. 21:6558-6566
The novel 2,7-bis((TIPS)ethynyl)-10b,10c-diethyldihydropyrene photochrome (TIPS = triisopropylsilyl) was observed to undergo thermal rearrangement to 2,7-bis(TIPS-ethynyl)-pyrene in the solid state...
Autor:
Marco Buccini, Francis Dhoro, Louisa Tham, Brian W. Skelton, Craig M. Williams, Matthew J. Piggott
Publikováno v:
ACS omega. 7(23)
Strategies toward the total synthesis of the marine pyrroloacridine alkaloid alpkinidine have been explored, focusing on linking quinonoid CE ring-system synthons with the A ring, followed by condensation to form the B and D rings. The key Michael ad
Autor:
Marco Buccini, Louisa Tham, Francis Dhoro, Brian W. Skelton, Craig M. Williams, Matthew J. Piggott
Publikováno v:
ACS omega. 7(23)
Model chemistry involving the bisannulation of 2,3-dichloro-1,4-naphthoquinone with the ester enolate derived from ethyl