Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Matthew J Pace"'
Autor:
Erin H Graf, Matthew J Pace, Bennett A Peterson, Lindsay J Lynch, Steve B Chukwulebe, Angela M Mexas, Farida Shaheen, Jeffrey N Martin, Steven G Deeks, Mark Connors, Stephen A Migueles, Una O'Doherty
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71879 (2013)
Resting CD4+T cells infected with HIV persist in the presence of suppressive anti-viral therapy (ART) and are barriers to a cure. One potential curative approach, therapeutic vaccination, is fueled by recognition of the ability of a subset of elite c
Externí odkaz:
https://doaj.org/article/dabe650649514ad59849e1e13aa204ee
Autor:
Matthew J Pace, Erin H Graf, Luis M Agosto, Angela M Mexas, Frances Male, Troy Brady, Frederic D Bushman, Una O'Doherty
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002818 (2012)
Despite the effectiveness of highly active antiretroviral therapy (HAART) in treating individuals infected with HIV, HAART is not a cure. A latent reservoir, composed mainly of resting CD4+T cells, drives viral rebound once therapy is stopped. Unders
Externí odkaz:
https://doaj.org/article/dbccde35766d4ad09774f366e3f2ac9f
Publikováno v:
Virology. 441:18-21
Treatment resistant latent reservoirs remain a barrier to cure HIV, but the maintenance and properties of these reservoirs are not completely understood. 2-LTR circular HIV DNA has been used to assess ongoing viral replication in HAART treated patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3095cec8a2f545d3905d62f1c07520
https://doi.org/10.1016/j.virol.2013.02.028
https://doi.org/10.1016/j.virol.2013.02.028
Publikováno v:
Virology. 411:344-354
The main impediment to a cure for HIV is the existence of long-lasting treatment resistant viral reservoirs. In this review, we discuss what is currently known about reservoirs, including their formation and maintenance, while focusing on latently in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ed45ccf0e4d49da46fb6cc86d683e1
https://doi.org/10.1016/j.virol.2010.12.041
https://doi.org/10.1016/j.virol.2010.12.041
Autor:
Clifford Baytop, Una O'Doherty, Luis M. Agosto, Matthew J. Pace, Jihong Dai, Jianqing J. Yu, Megan K. Liszewski
Publikováno v:
Journal of Virology. 83:4528-4537
Resting CD4+T cells restrict human immunodeficiency virus (HIV) infection at or before reverse transcription, resulting in slower kinetics of reverse transcription. In a previous study, we showed that, despite this restriction at reverse transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9b4faf3ba3f21bc0ab5d1f28444cc2
https://doi.org/10.1128/jvi.01910-08
https://doi.org/10.1128/jvi.01910-08
Autor:
Una O'Doherty, Matthew J. Pace
Publikováno v:
The Journal of Infectious Diseases. 207:1790-1792
(See the major article by McNamara et al on pages 1807–16.) New emphasis has been placed on curing human immunodeficiency virus (HIV) infection. Before we can eradicate HIV, we need to understand which cells are infected in vivo and which contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::696fe68118dc9b581f01ae174220ef18
https://doi.org/10.1093/infdis/jit120
https://doi.org/10.1093/infdis/jit120
Autor:
Erin H. Graf, Matthew J. Pace, Bennett A. Peterson, Lindsay J. Lynch, Steve B. Chukwulebe, Angela M. Mexas, Farida Shaheen, Jeffrey N. Martin, Steven G. Deeks, Mark Connors, Stephen A. Migueles, Una O’Doherty
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::e861fedb20ec08babf480d3fbd661728
http://europepmc.org/articles/PMC3935811
http://europepmc.org/articles/PMC3935811
Autor:
Angela M. Mexas, Una O'Doherty, Lindsay Lynch, Matthew J. Pace, Mark Connors, Steve B. Chukwulebe, Erin H. Graf, Jeffrey N. Martin, Steven G. Deeks, Stephen A. Migueles, Farida Shaheen, Bennett A. Peterson
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71879 (2013)
PLoS ONE
PLoS ONE
Resting CD4+ T cells infected with HIV persist in the presence of suppressive anti-viral therapy (ART) and are barriers to a cure. One potential curative approach, therapeutic vaccination, is fueled by recognition of the ability of a subset of elite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d389b52f4dc9c25322cb32db137759e
http://europepmc.org/articles/PMC3737195?pdf=render
http://europepmc.org/articles/PMC3737195?pdf=render
Autor:
Erin H. Graf, Luis M. Agosto, Una O'Doherty, Troy Brady, Matthew J. Pace, Frederic D. Bushman, Frances Male, Angela M. Mexas
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002818 (2012)
PLoS Pathogens
PLoS Pathogens
Despite the effectiveness of highly active antiretroviral therapy (HAART) in treating individuals infected with HIV, HAART is not a cure. A latent reservoir, composed mainly of resting CD4+T cells, drives viral rebound once therapy is stopped. Unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25c4c63e05ec86594476b76303f2d3e
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22911005/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22911005/pdf/?tool=EBI
Publikováno v:
Journal of virology. 85(1)
Naïve CD4 4 T cells are resistant to both HIV R5 env and vesicular stomatitis virus G protein (VSV-G)-mediated fusion. However, viral particles carrying both HIV R5 env and VSV-G infect naïve cells by an unexplained mechanism. We show that VSV-G-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988d4ab7eec85e00ed34e63dff6ef821
https://pubmed.ncbi.nlm.nih.gov/20980513
https://pubmed.ncbi.nlm.nih.gov/20980513