Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Matthew J Jackson"'
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Objectives Pharmaceutical innovation can contribute to reducing the burden of disease in human populations. This research asks whether products approved by the US Food and Drug Administration (FDA) from 2010 to 2019 and expedited review programmes in
Externí odkaz:
https://doaj.org/article/1f0a1b5e40fd4860bb581d03b4a078ff
Autor:
Jost Klawitter, Cristina Sempio, Matthew J. Jackson, Peter H. Smith, Katharina Hopp, Michel Chonchol, Berenice Y. Gitomer, Uwe Christians, Jelena Klawitter
Publikováno v:
Am J Nephrol
Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is a commonly inherited disorder characterized by renal cyst formation. A major pathological feature of ADPKD is the development of interstitial inflammation. The endocannabinoid (EC)
Autor:
Jost Klawitter, Matthew J. Jackson, Peter H. Smith, Katharina Hopp, Michel Chonchol, Berenice Y. Gitomer, Melissa A. Cadnapaphornchai, Uwe Christians, Jelena Klawitter
Publikováno v:
J Nephrol
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder, characterized by kidney cyst formation. A major pathological feature of ADPKD is the development of interstitial inflammation. Due to its role in inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c799dd365555500a43f3910cc5045158
https://europepmc.org/articles/PMC9867782/
https://europepmc.org/articles/PMC9867782/
Publikováno v:
JAMA Health Forum. 4:e230511
ImportanceGovernment and the pharmaceutical industry make substantive contributions to pharmaceutical innovation. This study compared the investments by the National Institutes of Health (NIH) and industry and estimated the cost basis for assessing t
Autor:
Callum Faris, Linda N. Lee, Nate Jowett, Olivia Quatela, Oren Tessler, Matthew J Jackson, Alyssa Heiser
Publikováno v:
The laryngoscope
Objectives Advanced nasal malignancies may require rhinectomy, which can have profound psychosocial impacts. Rhinectomy defects can be rehabilitated through surgery or prosthetics. We seek to understand the health utility of the rhinectomy defect, su
Publikováno v:
Pharmaceutical Research. 33:1276-1288
Excipients are essential for solubility enhancing formulations. Hence it is important to understand how additives impact key solution properties, particularly when supersaturated solutions are generated by dissolution of the solubility enhancing form
Publikováno v:
Molecular Pharmaceutics. 13:223-231
Amorphous solid dispersions (ASDs) are of great interest as enabling formulations because of their ability to increase the bioavailability of poorly soluble drugs. However, the dissolution of these formulations under nonsink dissolution conditions re
Autor:
Scott J. Toth, Garth J. Simpson, Matthew J. Jackson, Munir A. Hussain, Jun Huang, Feng Qian, Umesh S. Kestur, Lynne S. Taylor
Publikováno v:
Molecular Pharmaceutics. 11:3027-3038
The phase behavior of supersaturated solutions of a relatively hydrophobic drug, danazol, was studied in the absence and presence of polymeric additives. To differentiate between phase separation to a noncrystalline phase and phase separation to a cr
Publikováno v:
Crystal Growth & Design. 10:747-753
The purpose of this study was to examine how moisture affects the growth rate of felodipine crystals from amorphous systems. Amorphous felodipine films with 0−10% w/w poly(vinylpyrrolidone) (PVP) or hypromellose acetate succinate (HPMCAS) were prep
Autor:
Stella L, Ivaz, Rajan, Veeratterapillay, Matthew J, Jackson, Christopher K, Harding, Trevor J, Dorkin, Daniela E, Andrich, Anthony R, Mundy
Publikováno v:
Neurourology and urodynamics. 35(7)
Intermittent self-dilatation (ISD) may be recommended to reduce the risk of recurrent urethral stricture. Level one evidence to support the use of this intervention is lacking.Determine the clinical and cost-effectiveness of ISD for the management of