Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matthew J Eckwahl"'
Autor:
Denise Jurczyszak, Wen Zhang, Sandra N Terry, Thomas Kehrer, Maria C Bermúdez González, Emma McGregor, Lubbertus C F Mulder, Matthew J Eckwahl, Tao Pan, Viviana Simon
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008305 (2020)
N6-methyladenosine (m6A) is the most abundant HIV RNA modification but the interplay between the m6A reader protein YTHDF3 and HIV replication is not well understood. We found that knockout of YTHDF3 in human CD4+ T-cells increases infection supporti
Externí odkaz:
https://doaj.org/article/0171995c10ab48c9922f508557a02150
Autor:
Michael H. Schwartz, Haipeng Wang, Jessica N. Pan, Wesley C. Clark, Steven Cui, Matthew J. Eckwahl, David W. Pan, Marc Parisien, Sarah M. Owens, Brian L. Cheng, Kristina Martinez, Jinbo Xu, Eugene B. Chang, Tao Pan, A. Murat Eren
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The authors present a molecular approach and a software suite for high-throughput sequencing and characterization of microbial tRNA transcripts, which provide unique physiological insights into complex environmental microbes.
Externí odkaz:
https://doaj.org/article/6f8a3e52a3ef443084558e669d4b079b
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
ABSTRACT A fascinating aspect of retroviruses is their tendency to nonrandomly incorporate host cell RNAs into virions. In addition to the specific tRNAs that prime reverse transcription, all examined retroviruses selectively package multiple host ce
Externí odkaz:
https://doaj.org/article/178ebbd60db3474db43331c45e0d8686
Publikováno v:
RNA
Pseudouridine (Ψ) is the most abundant RNA modification in cellular RNA present in tRNA/rRNA/snRNA and also in mRNA and long noncoding RNA (lncRNA). Elucidation of Ψ function in mRNA/lncRNA requires mapping and quantitative assessment of its modifi
Publikováno v:
J Virol
RNA modifications play diverse roles in regulating RNA function, and viruses co-opt these pathways for their own benefit. While recent studies have highlighted the importance of N(6)-methyladenosine (m(6)A)—the most abundant mRNA modification—in
Autor:
Viviana Simon, Lubbertus C. F. Mulder, Tao Pan, Maria C. Bermúdez González, Wen Zhang, Denise Jurczyszak, Thomas Kehrer, Matthew J. Eckwahl, Sandra N. Terry, Emma McGregor
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008305 (2020)
PLoS Pathogens
PLoS Pathogens
N6-methyladenosine (m6A) is the most abundant HIV RNA modification but the interplay between the m6A reader protein YTHDF3 and HIV replication is not well understood. We found that knockout of YTHDF3 in human CD4+ T-cells increases infection supporti
Autor:
Nike Bharucha, Yeissa Chabrier-Rosello, Tao Xu, Cole Johnson, Sarah Sobczynski, Qingxuan Song, Craig J Dobry, Matthew J Eckwahl, Christopher P Anderson, Andrew J Benjamin, Anju Kumar, Damian J Krysan
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1002058 (2011)
The morphogenetic transition between yeast and filamentous forms of the human fungal pathogen Candida albicans is regulated by a variety of signaling pathways. How these pathways interact to orchestrate morphogenesis, however, has not been as well ch
Externí odkaz:
https://doaj.org/article/e021177aca1642e1b734c0fc4a4cb1af
Autor:
Marc Parisien, Jessica N. Pan, Brian L. M. Cheng, Jinbo Xu, Tao Pan, Michael H. Schwartz, David W. Pan, Haipeng Wang, A. Murat Eren, Eugene B. Chang, Wesley C. Clark, Steven Cui, Sarah M. Owens, Kristina Martinez, Matthew J. Eckwahl
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Advances in high-throughput sequencing have facilitated remarkable insights into the diversity and functioning of naturally occurring microbes; however, current sequencing strategies are insufficient to reveal physiological states of microbial commun
Publikováno v:
RNA biology. 15(7)
The abundant RNA modification pseudouridine (Ψ) has been mapped transcriptome-wide by chemically modifying pseudouridines with carbodiimide and detecting the resulting reverse transcription stops in high-throughput sequencing. However, these methods
Autor:
Tyson J. Edwards, Sandra L. Wolin, Jay R. Hesselberth, Sara Guckian Kosmaczewski, Marc Hammarlund, Sung Min Han, Benjamin Isaiah Meyer, Sally E. Peach, Matthew J. Eckwahl
Publikováno v:
EMBO reports. 15:1278-1285
RNA ligation can regulate RNA function by altering RNA sequence, structure and coding potential. For example, the function of XBP1 in mediating the unfolded protein response requires RNA ligation, as does the maturation of some tRNAs. Here, we descri