Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Matthew J, Szucs"'
Autor:
Monica E. Graham, Camille Merrick, Benjamin M. Akiyama, Matthew J. Szucs, Sarah Leach, Jeffery S. Kieft, J. David Beckham
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT All flaviviruses contain conserved RNA structures in the 3′ untranslated region (3′ UTR) that are important for flavivirus RNA replication, translation, and pathogenesis. Flaviviruses like Zika virus (ZIKV) contain multiple conserved RNA
Externí odkaz:
https://doaj.org/article/d5522a994a9d430da44cb34e19c0a423
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Viruses have developed innovative strategies to exploit the cellular machinery and overcome the antiviral defenses of the host, often using specifically structured RNA elements. Examples are found in the Flavivirus genus (in the family Flavi
Externí odkaz:
https://doaj.org/article/d1ae018e462d4548866e69c7eeefe8b4
Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types
Autor:
Benjamin E. Mead, Jose Ordovas-Montanes, Alexandra P. Braun, Lauren E. Levy, Prerna Bhargava, Matthew J. Szucs, Dustin A. Ammendolia, Melanie A. MacMullan, Xiaolei Yin, Travis K. Hughes, Marc H. Wadsworth, Rushdy Ahmad, Seth Rakoff-Nahoum, Steven A. Carr, Robert Langer, James J. Collins, Alex K. Shalek, Jeffrey M. Karp
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-24 (2018)
Abstract Background Single-cell genomic methods now provide unprecedented resolution for characterizing the component cell types and states of tissues such as the epithelial subsets of the gastrointestinal tract. Nevertheless, functional studies of t
Externí odkaz:
https://doaj.org/article/af6abd99fa9b45318eb28d7964c53335
Publikováno v:
J Proteome Res
Advances in protein tagging and mass spectrometry have enabled generation of large quantitative proteome and phosphoproteome data sets, for identifying differentially expressed targets in case-control studies. The power study of statistical tests is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d8cc3491e3f846ccf99703654ce3e5
https://doi.org/10.1021/acs.jproteome.9b00280
https://doi.org/10.1021/acs.jproteome.9b00280
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
Viruses have developed innovative strategies to exploit the cellular machinery and overcome the antiviral defenses of the host, often using specifically structured RNA elements. Examples are found in the Flavivirus genus (in the family Flaviviridae),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d5e50bc86389ebd460e7317e82e32a
https://journals.asm.org/doi/10.1128/mBio.02352-20
https://journals.asm.org/doi/10.1128/mBio.02352-20
Autor:
Steven A. Carr, Jen Q. Pan, Hongik Hwang, Rushdy Ahmad, Fan Gao, Hyewhon Rhim, Arturo Andrade, Matthew J. Szucs, Andrew S. Allen, Henny Haensgen, Xiaobai Ren, Weifeng Xu, Lei J. Ding
Publikováno v:
Biol Psychiatry
Background Neurogranin (Ng), encoded by the schizophrenia risk gene NRGN, is a calmodulin-binding protein enriched in the postsynaptic compartments, and its expression is reduced in the postmortem brains of patients with schizophrenia. Experience-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92ba92d9904524caeaef02e27a3db94
https://europepmc.org/articles/PMC9258036/
https://europepmc.org/articles/PMC9258036/
Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA
Autor:
Quentin Vicens, Rachel A. Jones, Anna-Lena Steckelberg, Jeffrey S. Kieft, Benjamin M. Akiyama, Matthew J. Szucs
Publikováno v:
RNA
During infection by a flavivirus (FV), cells accumulate noncoding subgenomic flavivirus RNAs (sfRNAs) that interfere with several antiviral pathways. These sfRNAs are formed by structured RNA elements in the 3′ untranslated region (UTR) of the vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4be5423068532630e8ca2f4358e3b6
https://pubmed.ncbi.nlm.nih.gov/33004436
https://pubmed.ncbi.nlm.nih.gov/33004436
Autor:
Quentin Vicens, Anna-Lena Steckelberg, Rachel A. Jones, Jeffrey S. Kieft, Benjamin M. Akiyama, Matthew J. Szucs
During infection by a flavivirus (FV), cells accumulate noncoding subgenomic flavivirus RNAs (sfRNAs) that interfere with several antiviral pathways. These sfRNAs are formed by structured RNA elements in the 3′ untranslated region (UTR) of the vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::037402a58fa54f4511348d8f25033669
https://doi.org/10.1101/2020.06.25.172429
https://doi.org/10.1101/2020.06.25.172429
Viruses have developed innovative strategies to exploit the cellular machinery and overcome the host antiviral defenses, often using specifically structured RNA elements. Examples are found in flaviviruses; during flaviviral infection, pathogenic sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eedbdc8a969737a0a9d516d9397ad77
https://doi.org/10.1101/2020.06.26.172668
https://doi.org/10.1101/2020.06.26.172668
Autor:
Michael R. Chase, Rushdy Ahmad, Vincent H Lin, Thibault Barbier, Jonathan Livny, Matthew J. Szucs, Brian Tjaden, Sarah M. Fortune, Raylin Xu, Jeremy M. Rock, Josie François, Elias R. Gerrick
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This work describes the most extensive discovery and functional characterization of small regulatory RNAs (sRNAs) in Mycobacterium tuberculosis to date. We comprehensively define the sRNAs expressed in M. tuberculosis under five host-lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2163334cf4feaf9a81088d0e108c91
https://doi.org/10.1073/pnas.1718003115
https://doi.org/10.1073/pnas.1718003115