Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Matthew J, Gavin"'
Autor:
Dominic Santoleri, Hee-Woong Lim, Matthew J. Emmett, Julian Stoute, Matthew J. Gavin, Jaimarie Sostre-Colón, Kahealani Uehara, Jaclyn E. Welles, Kathy Fange Liu, Mitchell A. Lazar, Paul M. Titchenell
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104410- (2022)
Summary: The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting an
Externí odkaz:
https://doaj.org/article/7c71e331dbf74cd59745668fc81b8721
Autor:
Jaimarie Sostre-Colón, Kahealani Uehara, Anna E. Garcia Whitlock, Matthew J. Gavin, Jeff Ishibashi, Matthew J. Potthoff, Patrick Seale, Paul M. Titchenell
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109128- (2021)
Summary: Organismal stressors such as cold exposure require a systemic response to maintain body temperature. Brown adipose tissue (BAT) is a key thermogenic tissue in mammals that protects against hypothermia in response to cold exposure. Defining t
Externí odkaz:
https://doaj.org/article/289a3505422f4442b608e9054f528a9d
Publikováno v:
Endocrinology
The hepatic transcription factor forkhead box O1 (FOXO1) is a critical regulator of hepatic and systemic insulin sensitivity. Previous work by our group and others demonstrated that genetic inhibition of FOXO1 improves insulin sensitivity both in gen
Autor:
Dominic, Santoleri, Hee-Woong, Lim, Matthew J, Emmett, Julian, Stoute, Matthew J, Gavin, Jaimarie, Sostre-Colón, Kahealani, Uehara, Jaclyn E, Welles, Kathy Fange, Liu, Mitchell A, Lazar, Paul M, Titchenell
Publikováno v:
iScience. 25(6)
The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting and refeedi