Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Matthew J, Emmett"'
Autor:
Dominic Santoleri, Hee-Woong Lim, Matthew J. Emmett, Julian Stoute, Matthew J. Gavin, Jaimarie Sostre-Colón, Kahealani Uehara, Jaclyn E. Welles, Kathy Fange Liu, Mitchell A. Lazar, Paul M. Titchenell
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104410- (2022)
Summary: The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting an
Externí odkaz:
https://doaj.org/article/7c71e331dbf74cd59745668fc81b8721
Autor:
Anthony R. Angueira, Suzanne N. Shapira, Jeff Ishibashi, Samay Sampat, Jaimarie Sostre-Colón, Matthew J. Emmett, Paul M. Titchenell, Mitchell A. Lazar, Hee-Woong Lim, Patrick Seale
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 2869-2878.e4 (2020)
Summary: Brown adipose tissue (BAT) activity protects animals against hypothermia and represents a potential therapeutic target to combat obesity. The transcription factor early B cell factor-2 (EBF2) promotes brown adipocyte differentiation, but its
Externí odkaz:
https://doaj.org/article/d2804c928ea74363a16d4ff9dbecff3a
Autor:
Steven B. Maron, Stephanie Moya, Federica Morano, Matthew J. Emmett, Joanne F. Chou, Shalom Sabwa, Henry Walch, Bryan Peterson, Alexa B. Schrock, Liangliang Zhang, Yelena Y. Janjigian, Sree Chalasani, Geoffrey Y. Ku, Umut Disel, Peter Enzinger, Nataliya Uboha, Shumei Kato, Takayuki Yoshino, Kohei Shitara, Yoshiaki Nakamura, Anwaar Saeed, Pashtoon M. Kasi, Joseph Chao, Jeeyun Lee, Marinela Capanu, Zev Wainberg, Russell Petty, Filippo Pietrantonio, Samuel J. Klempner, Daniel V.T. Catenacci
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(22)
PURPOSE Subset analyses from phase III evaluation of epidermal growth factor receptor inhibition (EGFRi) suggest improved outcomes in patients with EGFR-amplified gastroesophageal adenocarcinoma (GEA), but large-scale analyses are lacking. This multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ee62cb23649b256817d4d9451fdd86
https://pubmed.ncbi.nlm.nih.gov/35349370
https://pubmed.ncbi.nlm.nih.gov/35349370
Autor:
Hannah J. Richter, Amy K. Hauck, Kirill Batmanov, Shin-Ichi Inoue, Bethany N. So, Mindy Kim, Matthew J. Emmett, Ronald N. Cohen, Mitchell A. Lazar
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Brown adipose tissue (BAT) is a key thermogenic organ whose expression of uncoupling protein 1 (UCP1) and ability to maintain body temperature in response to acute cold exposure require histone deacetylase 3 (HDAC3). HDAC3 exists in tight association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce165f4221e30ffdd814a40b1237b086
https://doi.org/10.1073/pnas.2205276119
https://doi.org/10.1073/pnas.2205276119
Autor:
Yi-Ju Chen, Stacy R. Finkbeiner, Daniel Weinblatt, Matthew J. Emmett, Feven Tameire, Maryam Yousefi, Chenghua Yang, Rene Maehr, Qiao Zhou, Ruth Shemer, Yuval Dor, Changhong Li, Jason R. Spence, Ben Z. Stanger
Publikováno v:
Cell Reports, Vol 6, Iss 6, Pp 1046-1058 (2014)
The ability to interconvert terminally differentiated cells could serve as a powerful tool for cell-based treatment of degenerative diseases, including diabetes mellitus. To determine which, if any, adult tissues are competent to activate an islet β
Externí odkaz:
https://doaj.org/article/03b740775d9546bb896a3c8c5c944e3a
Autor:
Paul M. Titchenell, Patrick Seale, Jeff Ishibashi, Suzanne N. Shapira, Mitchell A. Lazar, Anthony R. Angueira, Hee-Woong Lim, Matthew J. Emmett, Samay Sampat, Jaimarie Sostre-Colón
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 2869-2878.e4 (2020)
Cell reports
Cell reports
SUMMARY Brown adipose tissue (BAT) activity protects animals against hypothermia and represents a potential therapeutic target to combat obesity. The transcription factor early B cell factor-2 (EBF2) promotes brown adipocyte differentiation, but its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0caa3320a252bbdbc20186ebd9563631
http://www.sciencedirect.com/science/article/pii/S2211124720301777
http://www.sciencedirect.com/science/article/pii/S2211124720301777
Autor:
Dominic, Santoleri, Hee-Woong, Lim, Matthew J, Emmett, Julian, Stoute, Matthew J, Gavin, Jaimarie, Sostre-Colón, Kahealani, Uehara, Jaclyn E, Welles, Kathy Fange, Liu, Mitchell A, Lazar, Paul M, Titchenell
Publikováno v:
iScience. 25(6)
The insulin responsive Akt and FoxO1 signaling axis is a key regulator of the hepatic transcriptional response to nutrient intake. Here, we used global run-on sequencing (GRO-seq) to measure the nascent transcriptional response to fasting and refeedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce773bade043e87e6634adbcac4f4525
https://pubmed.ncbi.nlm.nih.gov/35663017
https://pubmed.ncbi.nlm.nih.gov/35663017
Recurrent Hemoptysis and Bronchial Artery Abnormalities in a 64-Year-Old Man with Cannabinoid Vaping
Autor:
N. Mihatov, Matthew J. Emmett, J.M. Rodriguez-Lopez, S.A. Khetarpal, E. Wehrenberg-Klee, M. Theodore, D.S. Sinden
Publikováno v:
D39. CASE REPORTS IN VAPING INDUCED LUNG DISEASE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ba9c52d8a14ed99142954cf72c98a92
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6674
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6674
Autor:
Mitchell A. Lazar, Matthew J. Emmett
Publikováno v:
Nature Reviews Molecular Cell Biology. 20:102-115
Cell-type-specific gene expression is physiologically modulated by the binding of transcription factors to genomic enhancer sequences, to which chromatin modifiers such as histone deacetylases (HDACs) are recruited. Drugs that inhibit HDACs are in cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9963c7e69ff42cfbfd9b65b800671cea
https://doi.org/10.1038/s41580-018-0076-0
https://doi.org/10.1038/s41580-018-0076-0
Publikováno v:
The FASEB Journal. 32:5640-5646
Brown adipose tissue (BAT) thermogenic functions are primarily mediated by uncoupling protein (UCP)-1. Ucp1 gene expression is highly induced by cold temperature, via sympathetic nervous system and β-adrenergic receptors (βARs). Ucp1 is also repres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb0e1ea5fc9b549428f5067d32b6669
https://doi.org/10.1096/fj.201800452r
https://doi.org/10.1096/fj.201800452r