Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Matthew J, Comstock"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2478
We present an instrument that combines high-resolution optical tweezers and multicolor confocal fluorescence spectroscopy. Biological macromolecules exhibit complex conformation and stoichiometry changes in coordination with their motion and activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08d6b1b9dab925f896abab71d8827b09
https://pubmed.ncbi.nlm.nih.gov/36063322
https://pubmed.ncbi.nlm.nih.gov/36063322
Publikováno v:
Nature chemical biology
Telomere maintenance by telomerase is essential for continuous proliferation of human cells and is vital for the survival of stem cells and 90% of cancer cells. To compensate for telomeric DNA lost during DNA replication, telomerase processively adds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3e764eb861f52fb8f1acee551ba647
http://europepmc.org/articles/PMC7311264
http://europepmc.org/articles/PMC7311264
Publikováno v:
Biophysical Journal. 122:443a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83d30b49dc26cde491762c4c69f966f0
https://doi.org/10.1016/j.bpj.2022.11.2393
https://doi.org/10.1016/j.bpj.2022.11.2393
Autor:
Kasun B. Senanayake, Rajeev Yadav, Kyle D. Cotter, Eric M. Patrick, Andrea A. Putnam, Eckhard Jankowski, Matthew J. Comstock
Publikováno v:
Biophysical Journal. 122:10a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a44870d17be8e89e88c38dd9fa60010d
https://doi.org/10.1016/j.bpj.2022.11.283
https://doi.org/10.1016/j.bpj.2022.11.283
Publikováno v:
Optical Tweezers ISBN: 9781071622285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::984d3d51dfffb698a15fbdf86334ae3f
https://doi.org/10.1007/978-1-0716-2229-2_8
https://doi.org/10.1007/978-1-0716-2229-2_8
Publikováno v:
The Journal of Physical Chemistry A. 123:9612-9620
We present an instrument that combines high-resolution optical tweezers and multicolor confocal fluorescence spectroscopy along with automated single-molecule assembly. The multicolor allows the simultaneous observation of multiple molecules or multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10152076a35ea18a1e3f53207fb5148
https://doi.org/10.1021/acs.jpca.9b08282
https://doi.org/10.1021/acs.jpca.9b08282
Autor:
Matthew J. Comstock
Publikováno v:
Optical Trapping and Optical Micromanipulation XVII.
Fundamental processes of life are carried out within cells by nanometer-scale molecular machines. Understanding how these tiny machines work reveals the basic physical underpinnings of life as well as provides opportunities for technological and medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2de5b7328fe42101406fd877a15b406
https://doi.org/10.1117/12.2570694
https://doi.org/10.1117/12.2570694
Autor:
Zeliha Kilic, Ioannis Sgouralis, Wooseok Heo, Andrea Sottini, Kunihiko Ishii, Daniel Nettels, Matthew J. Comstock, Tahei Tahara, Benjamin Schuler, Steve Pressé
Publikováno v:
Biophysical Journal. 121:534a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8637497e54d8a66dde0bda4ef442005f
https://doi.org/10.1016/j.bpj.2021.11.2814
https://doi.org/10.1016/j.bpj.2021.11.2814
Autor:
Lisa J. Lapidus, Kevin Ching, Yujie Chen, Miles L Whitmore, Matthew J. Comstock, Dena Izadi, Joseph D Slivka
Publikováno v:
The Journal of Physical Chemistry B. 122:11155-11165
Over the past two decades, one of the standard models of protein folding has been the "two-state" model, in which a protein only resides in the folded or fully unfolded states with a single pathway between them. Recent advances in spatial and tempora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08cf149436d7e628a5875b6e5f1737d
https://doi.org/10.1021/acs.jpcb.8b06199
https://doi.org/10.1021/acs.jpcb.8b06199
Publikováno v:
Nucleic Acids Research
Despite its fundamental importance in cellular processes and abundant use in biotechnology, we lack a detailed understanding of the kinetics of nucleic acid hybridization. In particular, the identity of the transition state, which determines the kine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d9bab76937beb669c253b092c1349f
https://doi.org/10.1093/nar/gkw1173
https://doi.org/10.1093/nar/gkw1173