Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Matthew J, Bick"'
Autor:
Yang Hsia, Rubul Mout, William Sheffler, Natasha I. Edman, Ivan Vulovic, Young-Jun Park, Rachel L. Redler, Matthew J. Bick, Asim K. Bera, Alexis Courbet, Alex Kang, T. J. Brunette, Una Nattermann, Evelyn Tsai, Ayesha Saleem, Cameron M. Chow, Damian Ekiert, Gira Bhabha, David Veesler, David Baker
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
De novo design of self-assembling protein nanostructures and materials is of significant interest, however design of complex, multi-component assemblies is challenging. Here, the authors present a stepwise hierarchical approach to build such assembli
Externí odkaz:
https://doaj.org/article/8bb80e33cedb4e58856a97a798a217fd
Autor:
Quinton M. Dowling, Hannah E. Volkman, Elizabeth E. Gray, Sergey Ovchinnikov, Stephanie Cambier, Asim K. Bera, Banumathi Sankaran, Max R. Johnson, Matthew J. Bick, Alex Kang, Daniel B. Stetson, Neil P. King
Publikováno v:
Nature Structural & Molecular Biology. 30:72-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::327402f7257c88d20de19eff584d1a8d
https://doi.org/10.1038/s41594-022-00862-z
https://doi.org/10.1038/s41594-022-00862-z
Autor:
George Ueda, Aleksandar Antanasijevic, Jorge A Fallas, William Sheffler, Jeffrey Copps, Daniel Ellis, Geoffrey B Hutchinson, Adam Moyer, Anila Yasmeen, Yaroslav Tsybovsky, Young-Jun Park, Matthew J Bick, Banumathi Sankaran, Rebecca A Gillespie, Philip JM Brouwer, Peter H Zwart, David Veesler, Masaru Kanekiyo, Barney S Graham, Rogier W Sanders, John P Moore, Per Johan Klasse, Andrew B Ward, Neil P King, David Baker
Publikováno v:
eLife, Vol 9 (2020)
Multivalent presentation of viral glycoproteins can substantially increase the elicitation of antigen-specific antibodies. To enable a new generation of anti-viral vaccines, we designed self-assembling protein nanoparticles with geometries tailored t
Externí odkaz:
https://doaj.org/article/1cb71cd9d73d4231af8ba7577a9734db
Autor:
Zhe Li, Shunzhi Wang, Una Nattermann, Asim K. Bera, Andrew J. Borst, Matthew J. Bick, Erin C. Yang, William Sheffler, Byeongdu Lee, Soenke Seifert, Hannah Nguyen, Alex Kang, Radhika Dalal, Joshua M. Lubner, Yang Hsia, Hugh Haddox, Alexis Courbet, Quinton Dowling, Marcos Miranda, Andrew Favor, Ali Etemadi, Natasha I. Edman, Wei Yang, Banumathi Sankaran, Babak Negahdari, David Baker
SummaryProtein crystallization plays a central role in structural biology1, with broad impact2in pharmaceutical formulation3, drug delivery4, biosensing5, and biocatalysis6,7. Despite this importance, the process of protein crystallization remains po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97c9e49b9bf954ca7ba67cff48a16384
https://doi.org/10.1101/2022.11.18.517014
https://doi.org/10.1101/2022.11.18.517014
Autor:
Neville P. Bethel, Andrew J. Borst, Fabio Parmeggiani, Matthew J. Bick, TJ Brunette, Hannah Nguyen, Alex Kang, Asim K. Bera, Lauren Carter, Marcos C. Miranda, Ryan Kibler, Mila Lamb, Xinting Li, Banumathi Sankaran, David Baker
Molecular systems with coincident cyclic and superhelical symmetry axes have considerable advantages for materials design as they can be readily lengthened or shortened by changing the length of the constituent monomers. Among proteins, alpha helical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::979e13b368bbe7502885eee453b2b36b
https://doi.org/10.1101/2022.10.14.511843
https://doi.org/10.1101/2022.10.14.511843
Autor:
Matthew J Bick, Per J Greisen, Kevin J Morey, Mauricio S Antunes, David La, Banumathi Sankaran, Luc Reymond, Kai Johnsson, June I Medford, David Baker
Publikováno v:
eLife, Vol 6 (2017)
We describe the computational design of proteins that bind the potent analgesic fentanyl. Our approach employs a fast docking algorithm to find shape complementary ligand placement in protein scaffolds, followed by design of the surrounding residues
Externí odkaz:
https://doaj.org/article/318860fd73d04bffacfc4c21510e0e19
Autor:
William A. Catterall, Qi Xu, Daohua Jiang, Atsuko Uyeda, Jiayi Dou, Tamer M. Gamal El-Din, Tomoaki Matsuura, Yang Hsia, David Baker, Dan Ma, Matthew J. Bick, T. J. Brunette, Justin M. Kollman, Chunfu Xu, Hua Bai, Eric M. Lynch, Po-Ssu Huang, Gabriella Reggiano, Peilong Lu, Scott E. Boyken, Matthew C. Johnson, Xue Y. Pei, Frank DiMaio, Lance Stewart, Ben F. Luisi
Publikováno v:
Nature
Transmembrane channels and pores have key roles in fundamental biological processes1 and in biotechnological applications such as DNA nanopore sequencing2-4, resulting in considerable interest in the design of pore-containing proteins. Synthetic amph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b9825492d180b0abadeeb58f81bed8
http://europepmc.org/articles/PMC7483984
http://europepmc.org/articles/PMC7483984
Autor:
Frank DiMaio, Asim K. Bera, Christoffer Norn, Cameron M. Chow, Lauren Carter, Benjamin Basanta, David Baker, Inna Goreshnik, Matthew J. Bick
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Reengineering naturally occurring proteins to have new functions has had considerable impact on industrial and biomedical applications, but is limited by the finite number of known proteins. A promise of de novo protein design is to gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8030e9a2e291c5d9a6ba29029012191c
http://europepmc.org/articles/PMC7486743
http://europepmc.org/articles/PMC7486743
Autor:
T. J. Brunette, Matthew J. Bick, Justin M. Kollman, Jesse M Hansen, David Baker, Cameron M. Chow
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The ability to robustly control macromolecular shape on the nanometer length scale is important for a wide range of biomedical and materials applications. DNA nanotechnology has achieved considerable success in building up complex struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb96d7260044f8ad519b996a9e62984b
https://doi.org/10.1073/pnas.1908768117
https://doi.org/10.1073/pnas.1908768117
Autor:
Danai Moschidi, Andrew C. McShan, Daniel A. Fletcher, David Baker, Lauren Carter, Scott E. Boyken, Santrupti Nerli, Matthew J. Bick, Po-Ssu Huang, Nikolaos G. Sgourakis, Kathy Y. Wei
Publikováno v:
Proceedings of the National Academy of Sciences. 117:7208-7215
The plasticity of naturally occurring protein structures, which can change shape considerably in response to changes in environmental conditions, is critical to biological function. While computational methods have been used for de novo design of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67078d3aa8b6139faae337631e30e277
https://doi.org/10.1073/pnas.1914808117
https://doi.org/10.1073/pnas.1914808117