Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Matthew I. Wahl"'
Autor:
Roberta M. Kato, Yuko Kawakami, Christoph W. Turck, Julia Chu, David J. Rawlings, Owen N. Witte, Alexander Tarakhovsky, Matthew I. Wahl, Ruby S. Tabuchi, Shin W. Kang, Jiro Kitaura, Toshiaki Kawakami
Publikováno v:
The EMBO Journal. 20:5692-5702
Mutations in Bruton's tyrosine kinase (Btk) result in X-linked agammaglobulinemia (XLA) in humans and X-linked immunodeficiency (xid) in mice. While targeted disruption of the protein kinase C-beta (PKCbeta) gene in mice results in an immunodeficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbc757a801015676cfba02f9a482b06
https://doi.org/10.1093/emboj/20.20.5692
https://doi.org/10.1093/emboj/20.20.5692
Publikováno v:
Immunity. 13(2):243-253
Pre-B cell receptor (pre-BCR) expression is critical for B lineage development. The signaling events initiated by the pre-BCR, however, remain poorly defined. We demonstrate that lipid rafts are the major functional compartment for human pre-B cell a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e090f0002eb7c15989096a3c5e047fe
Publikováno v:
Proceedings of the National Academy of Sciences. 96:2221-2226
Bruton’s tyrosine kinase (Btk) is a critical transducer of signals originating from the B cell antigen receptor (BCR). Dosage, sequential phosphorylation, and protein interactions are interdependent mechanisms influencing Btk function. Phosphopepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632dedaede91436d415508b26939a2a4
https://doi.org/10.1073/pnas.96.5.2221
https://doi.org/10.1073/pnas.96.5.2221
Autor:
Kinga Szigeti, Sazuku Nisitani, Matthew I. Wahl, Tetsuro Watabe, Joyce Yamashiro, Owen N. Witte, Michelle M. Le Beau, George Thomas, Zhennen Gu, Elizabeth M. Davis, Massimo Loda, Robert E. Reiter
Publikováno v:
Proceedings of the National Academy of Sciences. 95:1735-1740
The identification of cell surface antigens is critical to the development of new diagnostic and therapeutic modalities for the management of prostate cancer. Prostate stem cell antigen (PSCA) is a prostate-specific gene with 30% homology to stem cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12352c809e780aaf81ef1e69fe26c504
https://doi.org/10.1073/pnas.95.4.1735
https://doi.org/10.1073/pnas.95.4.1735
Autor:
Roberta M. Kato, Hyunsun Park, Matthew I. Wahl, Andrew M. Scharenberg, David J. Rawlings, Anne-Catherine Fluckiger, Siqi Lin, Owen N. Witte, Jean-Pierre Kinet
Publikováno v:
Science. 271:822-825
Bruton's tyrosine kinase (BTK) is pivotal in B cell activation and development through its participation in the signaling pathways of multiple hematopoietic receptors. The mechanisms controlling BTK activation were studied here by examination of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3482aeae016d4a31d4e5ddf1f2f36ab0
https://doi.org/10.1126/science.271.5250.822
https://doi.org/10.1126/science.271.5250.822
Publikováno v:
Journal of Biological Chemistry. 267:10447-10456
We demonstrated previously tyrosine phosphorylation-dependent modulation of phospholipase C-gamma 1 (PLC-gamma 1) catalytic activity (Nishibe, S., Wahl, M. I., Hernandez-Sotomayor, S. M. T., Tonks, N. K., Rhee, S. G., and Carpenter, G. (1990) Science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ad388d18f3d090167862dacbd9d8d43
https://doi.org/10.1016/s0021-9258(19)50039-4
https://doi.org/10.1016/s0021-9258(19)50039-4
Autor:
Graham Carpenter, Matthew I. Wahl, Shunzo Nishibe, Sue Goo Rhee, Nicholas K. Tonks, S. M. Hernandez-Sotomayor
Publikováno v:
Science. 250:1253-1256
Phospholipase C-gamma 1 (PLC-gamma 1), an isozyme of the phosphoinositide-specific phospholipase C family, which occupies a central role in hormonal signal transduction pathways, is an excellent substrate for the epidermal growth factor (EGF) recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217476fbe7b096dbc56c9eec3a77ba33
https://doi.org/10.1126/science.1700866
https://doi.org/10.1126/science.1700866
Publikováno v:
Journal of Biological Chemistry. 265:3944-3948
The 145-kDa phospholipase C isozyme, PLC-gamma, is an excellent substrate for the epidermal growth factor (EGF) receptor both in vivo and in vitro. We now demonstrate that EGF treatment of HSC-1 cells, a human squamous cell carcinoma-derived cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813bfdeff3a7eab8e06e63896934e613
https://doi.org/10.1016/s0021-9258(19)39685-1
https://doi.org/10.1016/s0021-9258(19)39685-1
Autor:
Graham Carpenter, Marc C. Mumby, Gordon Todderud, S. M. Teresa Hernández‐Sotomayor, Shunzo Nishibe, Matthew I. Wahl
Publikováno v:
Ciba Foundation Symposium 164-Interactions Among Cell Signalling Systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2426c9a22365122031c505dd1dda2a5
https://doi.org/10.1002/9780470514207.ch14
https://doi.org/10.1002/9780470514207.ch14
Publikováno v:
International immunology. 18(1)
Bruton's tyrosine kinase (Btk) plays critical roles in B cell development and activation. Mutations of Btk cause X-linked agammaglobulinemia (XLA) in humans and X-linked immunodeficiency in mice. An Src homology domain 2-kinase linker region exists i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642cd91d07c222a5c447726c84681ba7
https://pubmed.ncbi.nlm.nih.gov/16291652
https://pubmed.ncbi.nlm.nih.gov/16291652