Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Matthew Holcomb"'
Publikováno v:
QRB Discovery, Vol 3 (2022)
Macrocycles represent an important class of ligands, both in natural products and designed drugs. In drug design, macrocyclizations can impart specific ligand conformations and contribute to passive permeation by encouraging intramolecular H-bonds. A
Externí odkaz:
https://doaj.org/article/6b6ac81b42d749f1ab07da43cc3aeb94
Autor:
Thibaut Laboute, Stefano Zucca, Matthew Holcomb, Dipak N. Patil, Chris Garza, Brittany A. Wheatley, Raktim N. Roy, Stefano Forli, Kirill A. Martemyanov
Publikováno v:
Science. 379:1352-1358
Glycine is a major neurotransmitter involved in several fundamental neuronal processes. The identity of the metabotropic receptor mediating slow neuromodulatory effects of glycine is unknown. We identified an orphan G protein–coupled receptor, GPR1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26eb9d7b73ab19817418d7501e89cd81
https://doi.org/10.1126/science.add7150
https://doi.org/10.1126/science.add7150
Autor:
Zoë C. Adams, Anthony P. Silvestri, Sorina Chiorean, Dillon T. Flood, Brian P. Balo, Yifan Shi, Matthew Holcomb, Shawn I. Walsh, Colleen A. Maillie, Gregory K. Pierens, Stefano Forli, K. Johan Rosengren, Philip E. Dawson
Publikováno v:
ACS Central Science. 9:648-656
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cd2c3835db3392b0ba584eb8990c51e
https://doi.org/10.1021/acscentsci.2c01462
https://doi.org/10.1021/acscentsci.2c01462
Autor:
Laszlo Erdodi, Matthew Calamia, Matthew Holcomb, Anthony Robinson, Lauren Rasmussen, Kevin Bianchini
Publikováno v:
Journal of Forensic Psychology Research and Practice. :1-17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1a8f42017dd6835b6b26a2cb1596771
https://doi.org/10.1080/24732850.2023.2168581
https://doi.org/10.1080/24732850.2023.2168581
Publikováno v:
Journal of Personality Assessment. :1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d29193f7b67df7c55e1827f8f566ccdf
https://doi.org/10.1080/00223891.2022.2114358
https://doi.org/10.1080/00223891.2022.2114358
Autor:
Giulia Bianco, Matthew Holcomb, Diogo Santos-Martins, Andreas Tillack, Althea Hansel-Harris, Stefano Forli
We describe the formalization of the reactive docking protocol, a method developed to model and predict reactions between small molecules and biological macromolecules. The method has been successfully used in a number of applications already, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7780ef9d6123710a3529710e0a989cf2
https://doi.org/10.26434/chemrxiv-2023-19v1v
https://doi.org/10.26434/chemrxiv-2023-19v1v
Autor:
Matthew Holcomb, Jackson Kilburg, Zach Wellens, Trevin Detwiler, Katya Harycki, Athanasios Petridis, Meredith Luttrell
Publikováno v:
Physiology. 38
Greater interest in long term space travel is creating demand to develop artificial gravity systems that minimize the negative effects of long-term microgravity exposure. However, due to practical constraints of understanding the physiological effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfd893fa77a4448ee7b6acb0ab3b8f65
https://doi.org/10.1152/physiol.2023.38.s1.5733589
https://doi.org/10.1152/physiol.2023.38.s1.5733589
Autor:
Kaitlyn, Abeare, Laura, Cutler, Kelly Y, An, Parveen, Razvi, Matthew, Holcomb, Laszlo A, Erdodi
Publikováno v:
Cognitive and Behavioral Neurology. 35:155-168
Abbreviated neurocognitive tests offer a practical alternative to full-length versions but often lack clear interpretive guidelines, thereby limiting their clinical utility.To replicate validity cutoffs for the Boston Naming Test-Short Form (BNT-15)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58696bb5845d30b59dd7da4f6ae372b
https://doi.org/10.1097/wnn.0000000000000304
https://doi.org/10.1097/wnn.0000000000000304
Publikováno v:
Journal of Forensic Psychology Research and Practice. 22:470-488
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d028806b5ff342c9f5c8847b5ff19e4
https://doi.org/10.1080/24732850.2021.2013361
https://doi.org/10.1080/24732850.2021.2013361
Autor:
Zoë C. Adams, Erika J. Olson, Tania L. Lopez-Silva, Zhengwen Lian, Audrey Y. Kim, Matthew Holcomb, Jörg Zimmermann, Ramkrishna Adhikary, Philip E. Dawson
Publikováno v:
Chemical Science. 13:10020-10028
The characterization of self-assembling molecules presents significant experimental challenges, especially when associated with phase separation or precipitation. Transparent window infrared (IR) spectroscopy leverages site-specific probes that absor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8401c9c6a0e143d922d663912e718666
https://doi.org/10.1039/d1sc06562a
https://doi.org/10.1039/d1sc06562a