Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Matthew Halpert"'
Autor:
Matthew Halpert, Chris Verrico, Shonda Wesson, Vanaja Konduri, Colby Hofferek, Jonathan Vazquez-Perez, Emek Blair, Kenneth Dunner, Pedram Salimpour, William K Decker
Publikováno v:
The Journal of Immunology. 204:67.11-67.11
Hemp-derived cannabidiol (CBD) is the major non-psychoactive component of cannabis and has been promoted as a potential treatment for a wide variety of disparate inflammatory conditions. Here we evaluated CBD for its ability to modulate the productio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f703fcecc0718193c429ca6516b5006
https://doi.org/10.4049/jimmunol.204.supp.67.11
https://doi.org/10.4049/jimmunol.204.supp.67.11
Autor:
Matthew Halpert, Jonathan Vasquez-Perez, Vanaja Konduri, Yunyu Chen, Dan Liang, Jonathan M. Levitt, William K. Decker
Publikováno v:
The Journal of Immunology. 200:109.11-109.11
CTLA-4, the target of the blockbuster cancer immunotherapeutic ipilimumab, is the best characterized of the T-cell immune checkpoints. In contrast to T-cell expressed CTLA-4, almost nothing is known about CTLA-4 expression or function in non-lymphoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66c701c7649706b4dca8bb6fe12c05fd
https://doi.org/10.4049/jimmunol.200.supp.109.11
https://doi.org/10.4049/jimmunol.200.supp.109.11
Autor:
Vanaja Konduri, Dan (Vivian) Liang, Matthew Halpert, Jonathan Levitt, Peter Hotez, Kathryn Jones, William Decker
Publikováno v:
The Journal of Immunology. 194:145.14-145.14
Chagas Disease, caused by infection with the protozoan parasite Trypanosoma cruzi, is a leading cause of heart disease and sudden cardiac death in Latin America, disproportionately affecting people living in resource-poor areas. Approved treatment is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb9fd920bf29f0dc65df70d6cc087b37
https://doi.org/10.4049/jimmunol.194.supp.145.14
https://doi.org/10.4049/jimmunol.194.supp.145.14
Autor:
Dan Liang, Matthew Halpert, Vanaja Konduri, Yunyu Chen, Doyeun Kim, Sunghoon Kim, Jonathan Levitt, William Decker
Publikováno v:
The Journal of Immunology. 194:128.9-128.9
Of professional antigen presenting cells, only the dendritic cells (DC) are regarded as initiators of adaptive immune responses. Previously we identified a Th1 polarizing phenotype from DCs loaded with overlapping (homologous) MHC class I and II dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a7f7dffc08ad4cec3625d37add5823d
https://doi.org/10.4049/jimmunol.194.supp.128.9
https://doi.org/10.4049/jimmunol.194.supp.128.9
Autor:
Matthew Halpert, Dan Liang, Vanaja Konduri, Robia Pautler, Sherry Klumpp, Ratan Bhardwaj, Jonathan Levitt, William Decker
Publikováno v:
The Journal of Immunology. 194:128.13-128.13
Attempts to treat cancer by vaccine immunotherapy have produced unsatisfactory results in part due to an inability to generate effective TH1 immunity. Here we demonstrate the existence of an elegant TH1 regulatory mechanism based upon release of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7756f0d429bc8bbb184801883ee6eabf
https://doi.org/10.4049/jimmunol.194.supp.128.13
https://doi.org/10.4049/jimmunol.194.supp.128.13
Autor:
Matthew Halpert, Vanaja Konduri, Dan Liang, Yunyu Chen, James Wing, Silke Paust, Jonathan Levitt, William Decker
Publikováno v:
The Journal of Immunology. 194:128.11-128.11
Cytotoxic T-Lymphocyte Associated protein-4 (CTLA-4), the target of the blockbuster cancer immunotherapeutic ipilimumab, is a regulatory molecule of the B7 superfamily known to inhibit T-cell responses by a variety of different mechanisms. While CTLA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a88579ef384af17a35f32f460269be4c
https://doi.org/10.4049/jimmunol.194.supp.128.11
https://doi.org/10.4049/jimmunol.194.supp.128.11
Autor:
Matthew Halpert, Julienne Cloud-Carstens, Matthew Collinson-Pautz, Dan Liang, Vanaja Konduri, Sherry Klump, Ratan Bhardwaj, Michael Berens, Robia Paulter, David Spencer, Jonathan Levitt, William Decker
Publikováno v:
The Journal of Immunology. 190:47.12-47.12
The current understanding of TH1 polarization and the central role dendritic cells (DC) play in skewing such a response engender hope that DC-based vaccines may ultimately be capable of promoting therapeutic efficacy against recalcitrant pathogens an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::685909cd88e80266394d11efe8ee0448
https://doi.org/10.4049/jimmunol.190.supp.47.12
https://doi.org/10.4049/jimmunol.190.supp.47.12
Publikováno v:
The Journal of Immunology. 186:102.24-102.24
TLT2 is one of four receptors conserved between mouse and human within the TREM locus, and is expressed on B cells, macrophages, and neutrophils. TLT2 ligation on murine macrophages induces the production of chemokines and growth factors, as evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b455365b7637d9cf2148eb8262b6cc01
https://doi.org/10.4049/jimmunol.186.supp.102.24
https://doi.org/10.4049/jimmunol.186.supp.102.24