Výsledky vyhledávání - "Matthew H. Lindner"

Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model

Autor: Tom G. Obrig, Regina M. Seaner, Seth H. Pincus, Matthew K. Stone, James K. Roche, Lisa K. Gross, Matthew H. Lindner

Publikováno v: Laboratory Investigation. 88:1178-1191

The role of the liver in fatal intoxication with the binary toxin ricin is undefined. Means to reverse pathological events in the liver and to gain host survival after exposure to this toxin have not been described. We report a robust 7/4+ neutrophil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67b12d8c60b071a9a622825ddfaf861
https://doi.org/10.1038/labinvest.2008.83

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p38 Mitogen-Activated Protein Kinase Mediates Lipopolysaccharide and Tumor Necrosis Factor Alpha Induction of Shiga Toxin 2 Sensitivity in Human Umbilical Vein Endothelial Cells

Autor: Matthew K. Stone, Matthew H. Lindner, Tom G. Obrig, Glynis L. Kolling

Publikováno v: Infection and Immunity. 76:1115-1121

Escherichia coliO157:H7 Shiga toxin 2 (Stx2), one of the causative agents of hemolytic-uremic syndrome, is toxic to endothelial cells, including primary cultured human umbilical vein endothelial cells (HUVEC). This sensitivity of cells to Stx2 can be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16cff9f35991ffe408bd511d706e5504
https://doi.org/10.1128/iai.01300-07

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