Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Matthew Guberman"'
Autor:
Matthew Guberman-Pfeffer
Publikováno v:
The Journal of Physical Chemistry B. 126:10083-10097
Autor:
Rimpy Dhingra, Inna Rabinovich-Nikitin, Sonny Rothman, Matthew Guberman, Hongying Gang, Victoria Margulets, Davinder S. Jassal, Keshav Narayan Alagarsamy, Sanjiv Dhingra, Carla Valenzuela Ripoll, Filio Billia, Abhinav Diwan, Ali Javaheri, Lorrie A. Kirshenbaum
Publikováno v:
Circulation. 146:934-954
Background: Cytokines such as tumor necrosis factor-α (TNFα) have been implicated in cardiac dysfunction and toxicity associated with doxorubicin (DOX). Although TNFα can elicit different cellular responses, including survival or death, the mechan
Autor:
Matthew Guberman-Pfeffer
Helical homopolymers of multiheme cytochromes catalyze biogeochemically significant electron transfers with a reported 103-fold variation in conductivity. Herein, classical molecular dynamics and hybrid quantum/classical molecular mechanics are used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10e49804412ab55f2a12688627fbe31d
https://doi.org/10.1101/2023.01.21.525004
https://doi.org/10.1101/2023.01.21.525004
Autor:
Matthew Guberman-Pfeffer
A helical homopolymer of the outer-membrane cytochrome type S (OmcS) was proposed to electrically connect a common soil bacterium, Geobacter sulfurreducens, with minerals and other microbes for biogeochemically important processes. OmcS exhibits a su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c0704ce31b7d073d5f1c5e7fbdadcfe
https://doi.org/10.1101/2022.08.01.502099
https://doi.org/10.1101/2022.08.01.502099
Autor:
Jonathon Gerstein, Inna Rabinovich-Nikitin, Rimpy Dhingra, Lorrie A. Kirshenbaum, Matthew Guberman
Publikováno v:
Biochemistry of Apoptosis and Autophagy ISBN: 9783030787981
Biochemistry of Apoptosis and Autophagy
Biochemistry of Apoptosis and Autophagy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d604b1369cfa6bb0be7a1766bb692c3b
https://doi.org/10.1007/978-3-030-78799-8_13
https://doi.org/10.1007/978-3-030-78799-8_13
Publikováno v:
Trends in Cardiovascular Medicine. 28:246-260
Autophagy is a catabolic process for eliminating macromolecules and damaged organelles by a highly regulated lysosomal pathway. Importantly, autophagy serves as an integral quality control mechanism by recycling cellular constituents for energy consu
Autor:
Floribeth Aguilar, Victoria Margulets, Rimpy Dhingra, Lorrie A. Kirshenbaum, Matthew Guberman
Publikováno v:
Circulation Research. 125
Nuclear Factor-κB (NF-κB) is ubiquitously present transcription factor that regulates a variety of cellular functions including cell survival. Herein, we show a critical role for NF-κB signaling in regulation of mitochondrial permeability transiti
Autor:
Victoria Margulets, Rimpy Dhingra, James A. Thliveris, Lorrie A. Kirshenbaum, Jonathon Gerstein, Matthew Guberman, Inna Rabinovich-Nikitin, Nicholas Madden, Hongying Gang
Publikováno v:
Cardiovascular Research
Aims The chemotherapy drug doxorubicin (Dox) is commonly used for treating a variety of human cancers; however, it is highly cardiotoxic and induces heart failure. We previously reported that the Bcl-2 mitochondrial death protein Bcl-2/19kDa interact
Autor:
Hilary Nepon, Rahul Jayas, Brooke Lieberman, Graham G. Maddaford, Pegah Afshar, Rimpy Dhingra, Lorrie A. Kirshenbaum, Johnathan Gerstein, Victoria Margulets, Matthew Guberman, Abhinav Dhingra
Publikováno v:
Free radical biologymedicine. 112
The Bcl-2 protein Bnip3 is crucial for provoking oxidative injury to mitochondria following anthracycline treatment or ischemia-reperfusion injury. Herein, we investigate the effects of the polyphenolic compound ellagic acid (EA) on Bnip3 mediated mi