Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Matthew Golding"'
Autor:
Kenton P. Arkill, Matthew Golding, Astrid F. Nottebaum, Monja Stein, Tamara Girbl, Charlotte Owen-Woods, Bin Ma, Régis Joulia, Anna Barkaway, Loïc Rolas, Mathieu-Benoit Voisin, Sussan Nourshargh, David O. Bates, Dietmar Vestweber
Publikováno v:
The Journal of Clinical Investigation
Increased microvascular permeability to plasma proteins and neutrophil emigration are hallmarks of innate immunity and key features of numerous inflammatory disorders. Although neutrophils can promote microvascular leakage, the impact of vascular per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd4075f5653906de97ad6b4e0682756
https://doi.org/10.1172/jci133661
https://doi.org/10.1172/jci133661
Autor:
Jennifer V. Bodkin, Tim Lämmermann, Matthew Golding, Ulrich H. von Andrian, Natalia Reglero-Real, Anna Barkaway, Cleo L. Bishop, Régis Joulia, Rebecca S. Saleeb, Mathieu-Benoit Voisin, Monja Stein, Robin N. Poston, Tamara Girbl, Charlotte Owen-Woods, David Voehringer, Tchern Lenn, Aude Thiriot, Laura Vázquez-Martínez, Axel Roers, Antal Rot, Johan Duchene, Sussan Nourshargh, Loïc Rolas
Publikováno v:
Immunity
Summary Aging is associated with dysregulated immune functions. Here, we investigated the impact of age on neutrophil diapedesis. Using confocal intravital microscopy, we found that in aged mice, neutrophils adhered to vascular endothelium in inflame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5825f93a6447cdca931b6d1ddd8a1d48
https://pubmed.ncbi.nlm.nih.gov/34260883
https://pubmed.ncbi.nlm.nih.gov/34260883
Autor:
Jose Garrido-Mesa, Dianne Cooper, Mauro Perretti, Catherine Pickworth, Matthew Golding, Tao Fu, Loïc Rolas, William A. Muller, Lucy M. Collinson, Ezra Aksoy, Maria Gonzalez-Nunez, Mathieu-Benoit Voisin, Thomas D. Nightingale, Natalia Reglero-Real, Laura Vázquez-Martínez, Shani Austin-Williams, Giulia De Rossi, Lorena Pérez-Gutiérrez, Sussan Nourshargh, Chantal M. Boulanger, Sharon A. Tooze, Yoshiaki Kubota, Anna Barkaway, Azumi Yoshimura, Rebeca S. Saleeb
Publikováno v:
Immunity
Summary The migration of neutrophils from the blood circulation to sites of infection or injury is a key immune response and requires the breaching of endothelial cells (ECs) that line the inner aspect of blood vessels. Unregulated neutrophil transen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee7732ddcf03fd2589976a2b6a36ae5
https://doi.org/10.1016/j.immuni.2021.07.012
https://doi.org/10.1016/j.immuni.2021.07.012
Autor:
Ambrosius P. Snijders, Lucy M. Collinson, Matthew Golding, David Villarroel-Campos, Giampietro Schiavo, Anne Weston, Marta I. Budzinska
Publikováno v:
Journal of Cell Science
Signalling by target-derived neurotrophins is essential for the correct development of the nervous system and its maintenance throughout life. Several aspects concerning the lifecycle of neurotrophins and their receptors have been characterised over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ecc4595adee00aed55e7497e05d2a20
https://pubmed.ncbi.nlm.nih.gov/32079660
https://pubmed.ncbi.nlm.nih.gov/32079660
Autor:
Paola Caccin, Kinga Bercsenyi, Giuseppe Zanotti, Giampietro Schiavo, Matthew Golding, Martin Wallace, Linda Greensmith, Roswitha Nischt, Nathalie Schmieg, J. Barney Bryson
Publikováno v:
Science. 346:1118-1123
Tetanus neurotoxin (TeNT) is among the most poisonous substances on Earth and a major cause of neonatal death in nonvaccinated areas. TeNT targets the neuromuscular junction (NMJ) with high affinity, yet the nature of the TeNT receptor complex remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7e1cbfa3f2fe8cf75303890775c822
https://doi.org/10.1126/science.1258138
https://doi.org/10.1126/science.1258138
Autor:
Hyota Takamatsu, Hajime Fujisawa, Atsushi Kumanogoh, Quenten Schwarz, Kathryn E. Waimey, Matthew Golding, Christiana Ruhrberg, Hwai-Jong Cheng
Publikováno v:
Developmental Biology. 324(1):1-9
In vertebrates, class 3 semaphorins (SEMA3) control axon behaviour by binding to neuronal cell surface receptors composed of a ligand binding subunit termed neuropilin (NRP) and a signal transduction subunit of the A-type plexin family (PLXNA). We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b78b0966f30bc5298576a80f7893f5
Autor:
Christer Betsholtz, Holger Gerhardt, David T. Shima, Rose Watson, Christiana Ruhrberg, Matthew Golding, Sofia Ioannidou, Hajime Fujisawa
Publikováno v:
Genes & Development. 16:2684-2698
Branching morphogenesis in the mammalian lung andDrosophila trachea relies on the precise localization of secreted modulators of epithelial growth to select branch sites and direct branch elongation, but the intercellular signals that control blood v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75164a916eeb8e443f092305b3dae1b4
https://doi.org/10.1101/gad.242002
https://doi.org/10.1101/gad.242002
Autor:
Kinga, Bercsenyi, Nathalie, Schmieg, J Barney, Bryson, Martin, Wallace, Paola, Caccin, Matthew, Golding, Giuseppe, Zanotti, Linda, Greensmith, Roswitha, Nischt, Giampietro, Schiavo
Publikováno v:
Science (New York, N.Y.). 346(6213)
Tetanus neurotoxin (TeNT) is among the most poisonous substances on Earth and a major cause of neonatal death in nonvaccinated areas. TeNT targets the neuromuscular junction (NMJ) with high affinity, yet the nature of the TeNT receptor complex remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb4f0ff1f59a04e7ecff72e96b0a0bfd
https://pubmed.ncbi.nlm.nih.gov/25430769
https://pubmed.ncbi.nlm.nih.gov/25430769
Autor:
Krzysztof B. Wicher, David Ish-Horowicz, Marco Terenzio, Giampietro Schiavo, Matthew Golding, Bradley Spencer-Dene, Ian Rosewell, Matthew R. G. Russell
We have identified a new function for the dynein adaptor Bicaudal D homolog 1 (BICD1) by screening a siRNA library for genes affecting the dynamics of neurotrophin receptor-containing endosomes in motor neurons (MNs). Depleting BICD1 increased the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37a2e09d23020b48f67c8c39b2a0725
https://europepmc.org/articles/PMC4198053/
https://europepmc.org/articles/PMC4198053/
Publikováno v:
The Journal of Cell Biology
Phosphatidylinositol 3-kinase (PI 3-kinase) is a lipid kinase which has been implicated in mitogenesis, protein trafficking, inhibition of apoptosis, and integrin and actin functions. Here we show using a green fluorescent protein–tagged p85 subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb68dcc0238f429f2fe9e831aaa7e5d
http://europepmc.org/articles/PMC2156137
http://europepmc.org/articles/PMC2156137