Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Matthew G. Voas"'
PCP and Wnt pathway components act in parallel during zebrafish mechanosensory hair cell orientation
Autor:
Joaquin Navajas Acedo, Matthew G. Voas, Richard Alexander, Thomas Woolley, Jay R. Unruh, Hua Li, Cecilia Moens, Tatjana Piotrowski
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Planar cell polarity (PCP) regulates hair cell orientation in the zebrafish lateral line. Here, the authors show that mutating Wnt pathway genes (wnt11f1, fzd7a/b, and gpc4) causes concentric hair cell patterns not regulated by PCP, thus showing PCP/
Externí odkaz:
https://doaj.org/article/6f012fa95fe24ae2a2db36aed2fcdecd
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 1, Pp 135-145 (2013)
SUMMARY Mutations in SEC63 cause polycystic liver disease in humans. Sec63 is a member of the endoplasmic reticulum (ER) translocon machinery, although it is unclear how mutations in SEC63 lead to liver cyst formation in humans. Here, we report the i
Externí odkaz:
https://doaj.org/article/9b7c2faad14d41c79cd14966e4379f41
Glia play multifaceted roles in nervous systems in response to injury. Depending on the species, extent of injury, and glial cell type in question, glia can help or hinder the regeneration of neurons. Studying glia in the context of successful regene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9553ccce03cc7ff64eaaa7dc8de2519f
https://doi.org/10.1101/2023.02.01.526519
https://doi.org/10.1101/2023.02.01.526519
PCP and Wnt pathway components act in parallel during zebrafish mechanosensory hair cell orientation
Autor:
Tatjana Piotrowski, Joaquin Navajas Acedo, Thomas E. Woolley, Hua Li, Richard Alexander, Matthew G. Voas, Cecilia B. Moens, Jay R. Unruh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
Planar cell polarity (PCP) plays crucial roles in developmental processes such as gastrulation, neural tube closure and hearing. Wnt pathway mutants are often classified as PCP mutants due to similarities between their phenotypes. Here, we show that
Autor:
Amanda S. Khan, Salvatore L Stella, Stephanie L. Grillo, Matthew G. Voas, Michael Grillo, Dillon S. McDevitt
Publikováno v:
Purinergic Signalling. 15:327-342
Adenosine is an endogenous nucleoside in the central nervous system that acts on adenosine receptors. These are G protein-coupled receptors that have four known subtypes: A1, A2A, A2B, and A3 receptors. In the present study, we aimed to map the locat
Autor:
Jason J Early, David A. Lyons, Matthew G. Voas, Jill M Williamson, Isaac H. Bianco, Rafael G. Almeida, Megan E Madden, William S. Talbot
Publikováno v:
Current Biology
Summary Myelination of axons by oligodendrocytes enables fast saltatory conduction. Oligodendrocytes are responsive to neuronal activity, which has been shown to induce changes to myelin sheaths, potentially to optimize conduction and neural circuit
Autor:
Jill M Williamson, Isaac H. Bianco, Megan E Madden, Matthew G. Voas, Rafael G. Almeida, William S. Talbot, David A. Lyons, Jason J Early
To study activity-regulated myelination, we imaged synaptic vesicle fusion along single axons in living zebrafish, and found, surprisingly, that axonal synaptic vesicle fusion is driven by myelination. This myelin-induced axonal vesicle fusion was en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1d11a925fd5e1d9676fe4513fed9700
https://doi.org/10.1101/2020.08.28.271593
https://doi.org/10.1101/2020.08.28.271593
Autor:
Joaquin Navajas Acedo, Matthew G. Voas, Richard Alexander, Thomas Woolley, Jay R. Unruh, Hua Li, Cecilia Moens, Tatjana Piotrowski
Cell polarity plays a crucial role during development of vertebrates and invertebrates. Planar Cell Polarity (PCP) is defined as the coordinated polarity of cells within a tissue axis and is essential for processes such as gastrulation, neural tube c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553a39cf240c672c8f2f48180e7e7ced
https://orca.cardiff.ac.uk/id/eprint/124727/1/pp197184_0_merged_1548775075.pdf
https://orca.cardiff.ac.uk/id/eprint/124727/1/pp197184_0_merged_1548775075.pdf
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 6, Iss 1, Pp 135-145 (2013)
Disease Models & Mechanisms, Vol 6, Iss 1, Pp 135-145 (2013)
Summary Mutations in SEC63 cause polycystic liver disease in humans. Sec63 is a member of the endoplasmic reticulum (ER) translocon machinery, although it is unclear how mutations in SEC63 lead to liver cyst formation in humans. Here, we report the i
Publikováno v:
Current Biology. 16:636-648
Summary Background Myelinated axons are essential for rapid conduction of action potentials in the vertebrate nervous system. Of particular importance are the nodes of Ranvier, sites of voltage-gated sodium channel clustering that allow action potent