Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Matthew G. Varga"'
Autor:
Robert S. Seitz, Michael E. Hurwitz, Tyler J. Nielsen, Daniel B. Bailey, Matthew G. Varga, Brian Z. Ring, Carrie F. Metts, Brock L. Schweitzer, Kimberly McGregor, Douglas T. Ross
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background The IO Score is a 27-gene immuno-oncology (IO) classifier that has previously predicted benefit to immune checkpoint inhibitor (ICI) therapy in triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC). It genera
Externí odkaz:
https://doaj.org/article/559b3f8416ed47f4ba8dbc1a517b7989
Autor:
Harsha Ranganath, Amit L. Jain, Justin R. Smith, Julie Ryder, Amina Chaudry, Emily Miller, Felicia Hare, Poojitha Valasareddy, Robert S. Seitz, David R. Hout, Matthew G. Varga, Brock L. Schweitzer, Tyler J. Nielsen, Janice Mullins, Douglas T. Ross, David R. Gandara, Gregory A. Vidal
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Immune checkpoint inhibitor (ICI) therapies represent a major advance in treating a variety of advanced-stage malignancies. Nevertheless, only a subset of patients benefit, even when selected based on approved biomarkers such as P
Externí odkaz:
https://doaj.org/article/ca410bdf72ce41f5b615b14aab591ed1
Autor:
Sudha B. Singh, Cristina N. Coffman, Matthew G. Varga, Amanda Carroll-Portillo, Cody A. Braun, Henry C. Lin
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Tight junctions (TJs) are essential components of intestinal barrier integrity and protect the epithelium against passive paracellular flux and microbial translocation. Dysfunctional TJ leads to leaky gut, a condition associated with diseases includi
Externí odkaz:
https://doaj.org/article/3be60681babc43d5a1716cc24657d5c2
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Sulfate Reducing Bacteria (SRB), usually rare residents of the gut, are often found in increased numbers (called a SRB bloom) in inflammatory conditions such as Inflammatory Bowel Disease (IBD), pouchitis, and periodontitis. However, the underlying m
Externí odkaz:
https://doaj.org/article/9ca4db81f911449e81edb9b746c054ec
Autor:
Matthew G. Varga, Cecily R. Wood, Julia Butt, Mackenzie E. Ryan, Wei-Cheng You, Kaifeng Pan, Tim Waterboer, Meira Epplein, Carrie L. Shaffer
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Infection with Helicobacter pylori is the single greatest risk factor for developing gastric adenocarcinoma. In prospective, population-based studies, seropositivity to the uncharacterized H. pylori proteins Hp0305 and Hp1564 was significantly associ
Externí odkaz:
https://doaj.org/article/7b11e63e84034911a0f7c4669bb4c193
Autor:
Jennifer M. Noto, Joseph P. Zackular, Matthew G. Varga, Alberto Delgado, Judith Romero-Gallo, Matthew B. Scholz, M. Blanca Piazuelo, Eric P. Skaar, Richard M. Peek
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Helicobacter pylori is the strongest risk factor for gastric adenocarcinoma; however, most infected individuals never develop this malignancy. Strain-specific microbial factors, such as the oncoprotein CagA, as well as environmental conditio
Externí odkaz:
https://doaj.org/article/4e1d7e064e0343d7a2ef53ea353bd1c7
Autor:
Amanda Carroll-Portillo, Cristina N. Coffman, Matthew G. Varga, Joe Alcock, Sudha B. Singh, Henry C. Lin
Publikováno v:
Viruses, Vol 13, Iss 2, p 328 (2021)
For decades, bacteriophage purification has followed structured protocols focused on generating high concentrations of phage in manageable volumes. As research moves toward understanding complex phage populations, purification needs have shifted to m
Externí odkaz:
https://doaj.org/article/3fa326070d6b4234b1fd9f77de5c296b
Autor:
Meira Epplein, Michael Pawlita, Tim Waterboer, Xiao-Ou Shu, You-lin Qiao, Sun Ha Jee, Jeongseon Kim, Sue K. Park, Keun-Young Yoo, Christian C. Abnet, Wei Zheng, Taichi Shimazu, Shoichiro Tsugane, Tianyi Wang, Matthew G. Varga, Julia Butt
Supplementary Table S1: Smoking and gastric cancer risk by time between blood draw and diagnosis, the H. pylori Biomarker Cohort Consortium (HpBCC) Supplementary Table S2: Smoking and gastric cancer risk by sex, the H. pylori Biomarker Cohort Consort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b9ef802655cca1abca437e225209d3
https://doi.org/10.1158/1940-6207.22534721
https://doi.org/10.1158/1940-6207.22534721
Autor:
Meira Epplein, Michael Pawlita, Tim Waterboer, Xiao-Ou Shu, You-lin Qiao, Sun Ha Jee, Jeongseon Kim, Sue K. Park, Keun-Young Yoo, Christian C. Abnet, Wei Zheng, Taichi Shimazu, Shoichiro Tsugane, Tianyi Wang, Matthew G. Varga, Julia Butt
Smoking is an established risk factor for gastric cancer development. In this study, we aimed to assess prospectively the association of smoking with gastric cancer risk in 1,446 non-cardia gastric cancer cases and 1,796 controls from China, Japan, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee41593f876de5d630cd5f69a69ada57
https://doi.org/10.1158/1940-6207.c.6547622.v1
https://doi.org/10.1158/1940-6207.c.6547622.v1
Autor:
David L. Saltman, Matthew G. Varga, Tyler J. Nielsen, Nicole S. Croteau, Heather M. Lockyer, Amit L. Jain, Gregory A. Vidal, David R. Hout, Brock L. Schweitzer, Robert S. Seitz, Douglas T. Ross, David R. Gandara
Publikováno v:
Clinical lung cancer.
Immune checkpoint inhibitors (ICI) are standard of care in advanced non-small cell lung cancer (NSCLC). However, not all patients benefit, even among PD-L1 tumor proportional score (TPS) ≥50%, indicating an unmet need for additional biomarkers such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b5e6b79875528b74f496ef67d2ed21
https://pubmed.ncbi.nlm.nih.gov/36564297
https://pubmed.ncbi.nlm.nih.gov/36564297