Table S1 from Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors

Autor: Matthew R. Steensma, Carrie R. Graveel, Mary E. Winn, Rosanna Dono, Flavio Maina, David G. Kirsch, Mark Chen, Diana M. Cardona, Vadim Khachaturov, Rebecca D. Dodd, Jamie Grit, Elissa A. Boguslawski, Julie Koeman, Zachary Madaj, Megan Bowman, Curt J. Essenburg, Elizabeth A. Tovar, Matthew G. Pridgeon, Jacqueline D. Peacock

Summary of R26-MET transgene localization.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79aaf570ce271ad4ccca243277b0ac6e
https://doi.org/10.1158/0008-5472.22419273.v1

Figure S1 from Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors

Autor: Matthew R. Steensma, Carrie R. Graveel, Mary E. Winn, Rosanna Dono, Flavio Maina, David G. Kirsch, Mark Chen, Diana M. Cardona, Vadim Khachaturov, Rebecca D. Dodd, Jamie Grit, Elissa A. Boguslawski, Julie Koeman, Zachary Madaj, Megan Bowman, Curt J. Essenburg, Elizabeth A. Tovar, Matthew G. Pridgeon, Jacqueline D. Peacock

Histological and MET copy number changes during MPNST progression.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bbc66f5ab92bd18e3e3631f58c9aaa
https://doi.org/10.1158/0008-5472.22419291.v1

Figure S3 from Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors

Autor: Matthew R. Steensma, Carrie R. Graveel, Mary E. Winn, Rosanna Dono, Flavio Maina, David G. Kirsch, Mark Chen, Diana M. Cardona, Vadim Khachaturov, Rebecca D. Dodd, Jamie Grit, Elissa A. Boguslawski, Julie Koeman, Zachary Madaj, Megan Bowman, Curt J. Essenburg, Elizabeth A. Tovar, Matthew G. Pridgeon, Jacqueline D. Peacock

Metaphase FISH analysis of R26-MET transgene.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926b369be03b2c143e01bf7028411984
https://doi.org/10.1158/0008-5472.22419285.v1

Figure S4 from Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors

Autor: Matthew R. Steensma, Carrie R. Graveel, Mary E. Winn, Rosanna Dono, Flavio Maina, David G. Kirsch, Mark Chen, Diana M. Cardona, Vadim Khachaturov, Rebecca D. Dodd, Jamie Grit, Elissa A. Boguslawski, Julie Koeman, Zachary Madaj, Megan Bowman, Curt J. Essenburg, Elizabeth A. Tovar, Matthew G. Pridgeon, Jacqueline D. Peacock

Interphase FISH demonstrates copy number gain of Met and Hgf in NF1-MET, NF1-P53, and NF1 MPNSTs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bad56eb2febc40eef66b5bc0ebd8f1
https://doi.org/10.1158/0008-5472.22419282

Genomic status of MET potentiates sensitivity to MET and MEK inhibition in NF1-related malignant peripheral nerve sheath tumors

Autor: Curt J. Essenburg, Diana M. Cardona, Jacqueline D. Peacock, Elissa Boguslawski, Vadim Khachaturov, Mary E. Winn, Flavio Maina, Rosanna Dono, Carrie R. Graveel, Mark Chen, Matthew R. Steensma, Julie Koeman, David G. Kirsch, Jamie Grit, Rebecca D. Dodd, Matthew G Pridgeon, Zachary Madaj, Megan J. Bowman, Elizabeth A. Tovar

Publikováno v: Cancer Research
Cancer Research, American Association for Cancer Research, 2018, 78 (13), pp.canres.3167.2017. ⟨10.1158/0008-5472.CAN-17-3167⟩
Cancer Research, 2018, 78 (13), pp.canres.3167.2017. ⟨10.1158/0008-5472.CAN-17-3167⟩

Malignant peripheral nerve sheath tumors (MPNST) are highly resistant sarcomas that occur in up to 13% of individuals with neurofibromatosis type I (NF1). Genomic analysis of longitudinally collected tumor samples in a case of MPNST disease progressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec2ab38a4e26be91c6c2a19c031bab4
https://hal.archives-ouvertes.fr/hal-02088433