Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Matthew G. Annis"'
Autor:
Marco Biondini, Camille Lehuédé, Sébastien Tabariès, Matthew G. Annis, Alain Pacis, Eric H. Ma, Christine Tam, Brian E. Hsu, Yannick Audet-Delage, Afnan Abu-Thuraia, Charlotte Girondel, Valerie Sabourin, Stephanie P. Totten, Mariana de Sá Tavares Russo, Gaëlle Bridon, Daina Avizonis, Marie-Christine Guiot, Julie St-Pierre, Josie Ursini-Siegel, Russell Jones, Peter M. Siegel
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103276- (2024)
Metabolic rewiring is essential for tumor growth and progression to metastatic disease, yet little is known regarding how cancer cells modify their acquired metabolic programs in response to different metastatic microenvironments. We have previously
Externí odkaz:
https://doaj.org/article/9541bdda466b464aac43f308bd0b1d8e
Autor:
Kyle Lewis, Rachel La Selva, Elias Maldonado, Matthew G. Annis, Ouafa Najyb, Eduardo Cepeda Cañedo, Stephanie Totten, Steven Hébert, Valérie Sabourin, Caitlynn Mirabelli, Emma Ciccolini, Camille Lehuédé, Luc Choinière, Mariana Russo, Daina Avizonis, Morag Park, Julie St-Pierre, Claudia L. Kleinman, Peter M. Siegel, Josie Ursini-Siegel
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103028- (2024)
Significant efforts have focused on identifying targetable genetic drivers that support the growth of solid tumors and/or increase metastatic ability. During tumor development and progression to metastatic disease, physiological and pharmacological s
Externí odkaz:
https://doaj.org/article/8bcb1cc7a7684f09b3d926e68c5a0e4c
Autor:
Sébastien Tabariès, Matthew G. Annis, Anthoula Lazaris, Stephanie K. Petrillo, Jennifer Huxham, Amri Abdellatif, Vincent Palmieri, Jaclyn Chabot, Radia M. Johnson, Steven Van Laere, Cornelis Verhoef, Yasmina Hachem, Sara Yumeen, Nicholas Meti, Atilla Omeroglu, Gulbeyaz Altinel, Zu-Hua Gao, Alan S. L. Yu, Dirk J. Grünhagen, Peter Vermeulen, Peter Metrakos, Peter M. Siegel
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Tabariès et al. describe that claudin 2 is a promoter of colorectal cancer liver metastasis. Furthermore, high Claudin-2 expression is associated with shorter time to liver-specific recurrence and is a biomarker of replacement type CRC liver metasta
Externí odkaz:
https://doaj.org/article/e2e152566dcd484a9e2503811a8a2aa7
Autor:
Kyle Lewis, Alex Kiepas, Jesse Hudson, Julien Senecal, Jacqueline R. Ha, Elena Voorand, Matthew G. Annis, Valerie Sabourin, Ryuhjin Ahn, Rachel La Selva, Sébastien Tabariès, Brian E. Hsu, Matthew J. Siegel, Matthew Dankner, Eduardo Cepeda Canedo, Mathieu Lajoie, Ian R. Watson, Claire M. Brown, Peter M. Siegel, Josie Ursini-Siegel
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-19 (2020)
Abstract Background The p66ShcA redox protein is the longest isoform of the Shc1 gene and is variably expressed in breast cancers. In response to a variety of stress stimuli, p66ShcA becomes phosphorylated on serine 36, which allows it to translocate
Externí odkaz:
https://doaj.org/article/3438a5e4c9ae4d46bf14a48ac898942d
Autor:
Matthew G. Annis, Veronique Ouellet, Jonathan P. Rennhack, Sylvain L’Esperance, Claudine Rancourt, Anne-Marie Mes-Masson, Eran R. Andrechek, Peter M. Siegel
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background The Fos-related antigen 1 (FRA-1) transcription factor promotes tumor cell growth, invasion and metastasis. Phosphorylation of FRA-1 increases protein stability and function. We identify a novel signaling axis that leads to increa
Externí odkaz:
https://doaj.org/article/9e9d826ca44a4555b9d14275fadf397d
Autor:
Brian E. Hsu, Sébastien Tabariès, Radia M. Johnson, Sylvia Andrzejewski, Julien Senecal, Camille Lehuédé, Matthew G. Annis, Eric H. Ma, Sandra Völs, LeeAnn Ramsay, Remi Froment, Anie Monast, Ian R. Watson, Zvi Granot, Russell G. Jones, Julie St-Pierre, Peter M. Siegel
Publikováno v:
Cell Reports, Vol 27, Iss 13, Pp 3902-3915.e6 (2019)
Summary: Neutrophils are phenotypically heterogeneous and exert either anti- or pro-metastatic functions. We show that cancer-cell-derived G-CSF is necessary, but not sufficient, to mobilize immature low-density neutrophils (iLDNs) that promote liver
Externí odkaz:
https://doaj.org/article/25f477ee241a49fb82076fe716b1a056
Publikováno v:
Oncogene. 41:4573-4590
Autor:
Peter M. Siegel, Keith T. Flaherty, Ian R. Watson, Thomas Hawthorne, Tibor Keler, Lynda Chin, Lawrence Kwong, Zhifeng Dong, Marco Biondini, Dennie T. Frederick, Matthew G. Annis, April A.N. Rose
Supplementary Fig. S1. Heatmap of mRNA expression for individual melanosomal differentiation antigens and a MITF transcriptional signature using a published dataset of melanoma samples (2). Supplementary Fig. S2. GPNMB expression is induced in multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cecd43a040d42cc367f57ae8ff5449
https://doi.org/10.1158/1078-0432.22468286
https://doi.org/10.1158/1078-0432.22468286
Autor:
Peter M. Siegel, Keith T. Flaherty, Ian R. Watson, Thomas Hawthorne, Tibor Keler, Lynda Chin, Lawrence Kwong, Zhifeng Dong, Marco Biondini, Dennie T. Frederick, Matthew G. Annis, April A.N. Rose
Contains supplementary methods, references and figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20139567e057bcc80d8b247c7d08f224
https://doi.org/10.1158/1078-0432.22468289
https://doi.org/10.1158/1078-0432.22468289
Autor:
Peter M. Siegel, Keith T. Flaherty, Ian R. Watson, Thomas Hawthorne, Tibor Keler, Lynda Chin, Lawrence Kwong, Zhifeng Dong, Marco Biondini, Dennie T. Frederick, Matthew G. Annis, April A.N. Rose
Purpose: To determine if BRAF and/or MEK inhibitor–induced GPNMB expression renders melanomas sensitive to CDX-011, an antibody-drug conjugate targeting GPNMB.Experimental Design: The Cancer Genome Atlas melanoma dataset was interrogated for a pane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5877192a5970c06be85a3782d929e1d0
https://doi.org/10.1158/1078-0432.c.6526892.v1
https://doi.org/10.1158/1078-0432.c.6526892.v1