Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Matthew G, Gold"'
Publikováno v:
eLife, Vol 12 (2023)
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is essential for long-term potentiation (LTP) of excitatory synapses that is linked to learning and memory. In this study, we focused on understanding how interactions between CaMKIIα and the acti
Externí odkaz:
https://doaj.org/article/b9b478aea4964d5792ca3e898e91df52
Autor:
Timothy W Church, Parul Tewatia, Saad Hannan, João Antunes, Olivia Eriksson, Trevor G Smart, Jeanette Hellgren Kotaleski, Matthew G Gold
Publikováno v:
eLife, Vol 10 (2021)
Interplay between the second messengers cAMP and Ca2+ is a hallmark of dynamic cellular processes. A common motif is the opposition of the Ca2+-sensitive phosphatase calcineurin and the major cAMP receptor, protein kinase A (PKA). Calcineurin dephosp
Externí odkaz:
https://doaj.org/article/5707d591c8234b0aac60d37cf11079ff
Autor:
Ian D. Coombs, David Soto, Thomas P. McGee, Matthew G. Gold, Mark Farrant, Stuart G. Cull-Candy
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
AMPA-type glutamate receptors, which mediate fast excitatory signaling throughout the brain, exhibit profound desensitization, causing a progressive current decline in the continued presence of agonist. Here authors show that homomeric Q/R edited AMP
Externí odkaz:
https://doaj.org/article/a50e120ec8be4c268b59eed05b410716
Autor:
Carolin Sailer, Fabian Offensperger, Alexandra Julier, Kai-Michael Kammer, Ryan Walker-Gray, Matthew G. Gold, Martin Scheffner, Florian Stengel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Oncoprotein E6 facilitates the E6AP-catalyzed ubiquitination of p53. Here, the authors study the structural basis of this process by qualitative and quantitative cross-linking mass spectrometry, providing insights into E6AP-E6-p53 complex assembly an
Externí odkaz:
https://doaj.org/article/665259f0303c4a7a8d8b890e1f4e21c3
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The A-kinase anchoring protein AKAP79 is regulated by calmodulin (CaM). Here, the authors use crosslinking coupled to mass spectrometry to identify the CaM-binding site in AKAP79 and present the structure of CaM bound to an AKAP79 peptide. The struct
Externí odkaz:
https://doaj.org/article/49cdec22e2cc46518168ece42a2d109f
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is essential for long-term potentiation (LTP) of excitatory synapses that is linked to learning and memory. In this study, we focused on understanding how interactions between CaMKIIα and the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7b76e34d3b75eeacfac4267d0464ac0
https://doi.org/10.1101/2022.12.04.519035
https://doi.org/10.1101/2022.12.04.519035
Publikováno v:
cAMP Signaling ISBN: 9781071622445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a778b320bb4db7214846d292fe0dea4c
https://doi.org/10.1007/978-1-0716-2245-2_2
https://doi.org/10.1007/978-1-0716-2245-2_2
Autor:
Matthew G. Gold, João Antunes, Trevor G. Smart, Parul Tewatia, Olivia Eriksson, Saad Hannan, Jeanette Hellgren Kotaleski, Timothy W Church
Publikováno v:
eLife, Vol 10 (2021)
eLife, Vol. 10
eLife
eLife, Vol. 10
eLife
Interplay between the second messengers cAMP and Ca2+ is a hallmark of dynamic cellular processes. A common motif is the opposition of the Ca2+-sensitive phosphatase calcineurin and the major cAMP receptor, protein kinase A (PKA). Calcineurin dephosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a482282e710443ecb62872c35e881f93
https://elifesciences.org/articles/68164
https://elifesciences.org/articles/68164
Autor:
Trevor G. Smart, Saad Hannan, Jeanette Hellgren Kotaleski, Parul Tewatia, Matthew G. Gold, Olivia Eriksson, João Antunes, Timothy W Church
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a61fe525ed30adbe747333e58f7adc2
https://doi.org/10.7554/elife.68164.sa2
https://doi.org/10.7554/elife.68164.sa2
Autor:
Neha ePatel, Matthew G Gold
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Intracellular fluctuations of the second messenger cyclic AMP (cAMP) are regulated with spatial and temporal precision. This regulation is supported by the sophisticated arrangement of cyclases, phosphodiesterases, anchoring proteins and receptors fo
Externí odkaz:
https://doaj.org/article/7b9dcb9622dc41f9b28ac5826de52cc1