Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Matthew Furgerson"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44996 (2012)
The main pathological hallmarks of Alzheimer's disease are amyloid-beta plaques and neurofibrillary tangles, which are primarily composed of amyloid precursor protein (APP) and tau, respectively. These proteins and their role in the mechanism of neur
Externí odkaz:
https://doaj.org/article/10041a6dfa83495b9757551b5861f6c8
Autor:
Britt Johnson, Kathleen Crosby, Matthew Furgerson, Fernanda Leal-Pardinas, Asia Mitchell, Jennifer Pappadakis, Alex Solyom, Heather McLaughlin
Publikováno v:
Molecular Genetics and Metabolism. 135:281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::207b20eab41e1874d8b16f41e1293f22
https://doi.org/10.1016/j.ymgme.2022.01.055
https://doi.org/10.1016/j.ymgme.2022.01.055
Autor:
Heather M. McLaughlin, Michele Clarke, Kathleen Crosby, Matthew Furgerson, Fernanda Leal-Pardinas, Asia Mitchell, Jennifer A. Pappadakis, Alexander Solyom, Jenna Tress, Britt A. Johnson
Publikováno v:
Molecular Genetics and Metabolism. 135:S81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d51e9f2fe6a0222835ad363208add3d4
https://doi.org/10.1016/j.ymgme.2021.11.209
https://doi.org/10.1016/j.ymgme.2021.11.209
Autor:
Matthew Furgerson, Estelle Gefteas, Sarah Geller, Yunxiang Zhu, Alla Kloss, Malgorzata Przybylska, Seng H. Cheng, Nelson S. Yew, Adam M. Belanger
The neuropathological effects of phenylketonuria (PKU) stem from the inability of the body to metabolize excess phenylalanine (Phe), resulting in accumulation of Phe in the blood and brain. Since the kidney normally reabsorbs circulating amino acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9177507588da3a3d64ad6eca1b129f06
https://europepmc.org/articles/PMC6124451/
https://europepmc.org/articles/PMC6124451/
Autor:
Jason K. Clark, Jonathon D. Crystal, Ruth Furukawa, Marcus Fechheimer, John J. Wagner, Matthew Furgerson
Publikováno v:
Neurobiology of learning and memory. 125
Alzheimer's disease is a neurodegenerative condition believed to be initiated by production of amyloid-beta peptide, which leads to synaptic dysfunction and progressive memory loss. Using a mouse model of Alzheimer's disease (3xTg-AD), an 8-arm radia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a018b5490512e6944617ca2dc516fe
https://pubmed.ncbi.nlm.nih.gov/26385257
https://pubmed.ncbi.nlm.nih.gov/26385257
Autor:
Parker Evans, Ruth Furukawa, William Spears, John Michael Sweetnam, Marcus Fechheimer, Matthew Furgerson, Marla Gearing
Publikováno v:
BMC Neuroscience
Background Hirano bodies are actin-rich paracrystalline inclusions found in brains of patients with Alzheimer’s disease (AD), frontotemporal dementia (FTD), and in normal aged individuals. Although studies of post-mortem brain tissue provide clues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b743d7dda1ec957fe69719ed02ccbfd2
https://doi.org/10.1186/1471-2202-15-74
https://doi.org/10.1186/1471-2202-15-74
Autor:
Matthew Furgerson, Kathyrn L Bruce, Jessica L Snell, Alison J Farrell, Michael L. Gleason, Katherine A Keltner, David B. Nix, Mark F Law
Publikováno v:
International Journal of Biology. 3
Kex2p and furin are well-characterized, structurally similar, membrane-bound proteases localized to the trans-Golgi network (TGN) of yeast and animal cells. While their N-terminal and lumenal catalytic domains are highly homologous, they do not share
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1deb4289ba8f285d12fc77b69c7af0d
https://doi.org/10.5539/ijb.v3n3p3
https://doi.org/10.5539/ijb.v3n3p3
Autor:
Jonathon D. Crystal, Marcus Fechheimer, John J. Wagner, Jason K. Clark, Ruth Furukawa, Matthew Furgerson
Publikováno v:
Acta Neuropathologica Communications
Introduction Hirano bodies are actin-rich intracellular inclusions found in the brains of patients with neurodegenerative conditions such as Alzheimer's disease or frontotemporal lobar degeneration-tau. While Hirano body ultrastructure and protein co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3b99eb16e64d1b25c9733788505101