Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Matthew Flamm"'
Autor:
Samantha Hurley, Anthony Tantuccio, Manuel Sebastian Escotet-Espinoza, Matthew Flamm, Matthew Metzger
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 355 (2022)
Residence-time-distribution (RTD)-based models are key to understanding the mixing dynamics of continuous manufacturing systems. Such models can allow for material traceability throughout the process and can provide the ability for removal of non-con
Externí odkaz:
https://doaj.org/article/8aea15ccdb204122923efdfd7831d4f3
Autor:
Anthony Tantuccio, Matt Metzger, Seo-Young Park, Huolong Liu, Zhuangrong Huang, Matthew Flamm, Shaun C. Galbraith, Bumjoon Cha, Seongkyu Yoon
Publikováno v:
Pharmaceutical Development and Technology. 25:1204-1215
Continuous manufacturing of oral-dosage drug products is increasing the need for rigorous process understanding both from a process design and control perspective. The purpose of this study is to develop a methodology that analyzes the effects of ups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6090043a8072a9e890bd0b43ea3dd4c
https://doi.org/10.1080/10837450.2020.1805760
https://doi.org/10.1080/10837450.2020.1805760
Autor:
Seo-Young Park, Robert F. Meyer, Zhuangrong Huang, Seongkyu Yoon, Matthew Metzger, Huolong Liu, S. Hurley, Shaun C. Galbraith, Matthew Flamm
Publikováno v:
Chemical Engineering Research and Design. 153:85-95
Continuous manufacturing of oral-dosage pharmaceuticals is widely understood to ensure consistent product quality and higher productivity at lower costs. Here, a hybrid flowsheet model is developed in order to link the process variables to the reside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a43c3e8fa6421aeff55a67e7997fa64
https://doi.org/10.1016/j.cherd.2019.10.026
https://doi.org/10.1016/j.cherd.2019.10.026
Autor:
Bumjoon Cha, Huolong Liu, F. Zhang-Plasket, Zhuangrong Huang, Shaun C. Galbraith, Robert F. Meyer, Matthew Flamm, Seongkyu Yoon, S. Hurley, Seo-Young Park
Publikováno v:
Powder Technology. 354:199-210
A flowsheet model for a continuous direct compression tableting process is developed and applied to process data generated at production scale. The model contains powder feeding, blending and tablet compaction unit operations. The dataset was provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::863a022ca8609ac3c31ce640926351e4
https://doi.org/10.1016/j.powtec.2019.05.078
https://doi.org/10.1016/j.powtec.2019.05.078
Autor:
Robert F. Meyer, Matthew Metzger, Laura Wareham, Matthew Flamm, Huolong Liu, Anthony Tantuccio, Seongkyu Yoon
Publikováno v:
AAPS PharmSciTech. 22
In this study, the novel high-speed tablet film coating process in the continuous manufacturing was investigated. The influence of key process variables (inlet air flow rate, inlet air temperature, and suspension spray rate) were investigated using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d94059a6a8f89bf16cd9f858d01f8a2
https://doi.org/10.1208/s12249-020-01884-w
https://doi.org/10.1208/s12249-020-01884-w
Autor:
Camille L. Bilodeau, Giorgio Carta, Eric von Lieres, Steve Benner, Deenesh Kavi Babi, Philipp Ernst, Oleksandr Zavalov, John P. Welsh, Jan Griesbach, Marcel Stenvang, Larry Sun, Ernst Broberg Hansen, Arne Staby, S. Hunt, Thomas Wucherpfennig, Emmanouil Papadakis, Dilip Asthagiri, Matthew Flamm, Mark Fedesco, Sean Fitzgibbon, Bruno F. Marques, David J. Roush, Jasper C. Lin, Richard C. Willson, Fabrice Schlegel, Francis Insaidoo, Henrik S. Marke, Gang Wang, Tobias Grosskopf, Abraham M. Lenhoff, Peter M. Tessier, Tobias Hahn, R. Todd
Publikováno v:
Biotechnology & bioengineering 117(12), 3986-4000 (2020). doi:10.1002/bit.27520
The Third Modeling Workshop focusing on bioprocess modeling was held in Kenilworth, NJ in May 2019. A summary of these Workshop proceedings is captured in this manuscript. Modeling is an active area of research within the biotechnology community, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439240129d8f91f7f1d2274d485c9aa6
https://hdl.handle.net/2128/27001
https://hdl.handle.net/2128/27001
Autor:
Robert F. Meyer, Sau L. Lee, Seo-Young Park, Matthew Flamm, Shaun C. Galbraith, Bumjoon Cha, Seongkyu Yoon, Zhuangrong Huang, Huolong Liu, Thomas F. O’Connor
Publikováno v:
Pharmaceutical Development and Technology. 24:105-117
In this study, a novel three-compartmental population balance model (PBM) for a continuous twin screw wet granulation process is developed, combining the techniques of PBM and regression process modeling. The developed model links screw configuration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39f60ec59489fd2e8617b11615cbecb
https://doi.org/10.1080/10837450.2018.1427106
https://doi.org/10.1080/10837450.2018.1427106
Publikováno v:
Virology. 537
We present a novel kinetic Monte Carlo model to simulate the real process time-scale of the assembly of Human Papillomavirus (HPV) virus-like particles (VLPs) incorporating the formation of intercapsomeric disulfide bonds. The objective was to develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727afc24ab2275c71970a0109d45f392
https://pubmed.ncbi.nlm.nih.gov/31450047
https://pubmed.ncbi.nlm.nih.gov/31450047
The Quarrel Between Poetry and Philosophy: Perspectives Across the Humanities is an interdisciplinary study of the abiding quarrel to which poet-philosopher Plato referred centuries ago in the Republic. The book presents eight chapters by four humani
Publikováno v:
Journal of Colloid and Interface Science. 299:696-702
When one sphere adheres to a second sphere, the location or orientation of the adhesion on the second sphere is seldom considered. However, when a sphere adheres to a prolate spheroid, the orientation of the adhesion is sometimes critical. We have pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6d6caed92cb4e6c4dc1f1c0a8e2dde
https://doi.org/10.1016/j.jcis.2006.02.052
https://doi.org/10.1016/j.jcis.2006.02.052