Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Matthew F. Cuttle"'
Autor:
Francis C. Chee, Amritpal Mudher, Matthew F. Cuttle, Tracey A. Newman, Daniel MacKay, Simon Lovestone, David Shepherd
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 918-928 (2005)
We have shown that over-expression of human tau (0N3R) in Drosophila larval motor neurons causes significant morphological and functional disruption to the neuromuscular junctions (NMJs). Tau-expressing NMJs are reduced in size with irregular and abn
Externí odkaz:
https://doaj.org/article/3c32ecb1178c454e98f0bdd9d9cd4c78
Publikováno v:
Developmental Neurobiology. 67:219-232
Insects, like other animals, require sodium chloride (NaCl) as part of their normal diet and detect it with contact chemoreceptors on the body surface. By adjusting the responsiveness of the chemosensory neurons within these receptors insects can mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7304a8b5a9aa8d8e0ea39ac6c0d65561
https://doi.org/10.1002/dneu.20343
https://doi.org/10.1002/dneu.20343
Autor:
J. Willson, Neline Kriek, Kiran Amliwala, Alan Cook, Achim Harder, Vincent O'Connor, Robert J. Walker, Lindy Holden-Dye, Neil A. Hopper, Matthew F. Cuttle, Andrew Davis
Publikováno v:
Current Biology. 14(15):1374-1379
α-latrotoxin (LTX), a 120 kDa protein in black widow spider venom, triggers massive neurotransmitter exocytosis. Previous studies have highlighted a role for both intrinsic pore-forming activity and receptor binding in the action of this toxin [1].
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6833b4b1cb1501b00da9ab8d520fe75d
Publikováno v:
Journal of Neurophysiology
Journal of Neurophysiology, American Physiological Society, 2002, 88 (6), pp.2963-2978. ⟨10.1152/jn.00244.2002⟩
Journal of Neurophysiology, American Physiological Society, 2002, 88 (6), pp.2963-2978. ⟨10.1152/jn.00244.2002⟩
Extra- and intracellular records were made from rat acute hippocampal slices to examine the effects of partial inhibition of Na+-K+-ATPases (Na+-K+pumps) on neuronal hyperexcitability. Bath application of the low-affinity cardiac glycoside, dihydroou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d926977b5668bfafacda53453789bd
https://doi.org/10.1152/jn.00244.2002
https://doi.org/10.1152/jn.00244.2002
Publikováno v:
The Journal of Physiology. 512:723-729
1. The presynaptic calcium current (IpCa) was recorded from the calyx of Held in rat brainstem slices using the whole-cell patch clamp technique. 2. Tetanic activation of IpCa by 1 ms depolarizing voltage steps markedly enhanced the amplitude of IpCa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479396f099dba6fe6b3c18337aca70a2
https://doi.org/10.1111/j.1469-7793.1998.723bd.x
https://doi.org/10.1111/j.1469-7793.1998.723bd.x
Autor:
Amritpal Mudher, David Shepherd, Daniel Mackay, Simon Lovestone, Tracey A. Newman, Matthew F. Cuttle, Francis Chee
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 918-928 (2005)
Synaptic dysfunction is believed to be an early pathological change in neurodegenerative diseases and may cause the earliest clinical symptoms. We have used Drosophila to model a tauopathy in order to analyse the earliest neuronal and synaptic dysfun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739b28e7d75b95ffe9e851b64ef1ea64
https://pubmed.ncbi.nlm.nih.gov/16023860
https://pubmed.ncbi.nlm.nih.gov/16023860
Publikováno v:
Journal of neurobiology. 53(3)
We have analyzed the synthesis of nitric oxide in the terminal abdominal ganglion of the crayfish using the fluorescent probe 4,5-Diaminofluoroscein diacetate, DAF-2 DA. Following DAF-2 loading, ganglia showed cell-specific patterns of fluorescence i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22acd3bb1c412be0f76883091753914
https://pubmed.ncbi.nlm.nih.gov/12382263
https://pubmed.ncbi.nlm.nih.gov/12382263
Publikováno v:
The Journal of physiology. 534(Pt 3)
1. A hyperpolarization-activated non-specific cation current, I(h), was examined in bushy cell bodies and their giant presynaptic terminals (calyx of Held). Whole-cell patch clamp recordings were made using an in vitro brain slice preparation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d234a96af49c4d0c3a8cc0d53792acf
https://pubmed.ncbi.nlm.nih.gov/11483704
https://pubmed.ncbi.nlm.nih.gov/11483704
Autor:
Tetsuhiro Tsujimoto, Matthew F. Cuttle, Ian D. Forsythe, Margaret Barnes-Davies, Tomoyuki Takahashi
Publikováno v:
Neuron. 20(4)
Voltage-gated calcium channels are well characterized at neuronal somata but less thoroughly understood at the presynaptic terminal where they trigger transmitter release. In order to elucidate how the intrinsic properties of presynaptic calcium chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3a504d05c1c02359b36b046d6469d9
https://pubmed.ncbi.nlm.nih.gov/9581770
https://pubmed.ncbi.nlm.nih.gov/9581770
Publikováno v:
Biochemical Society Transactions. 29:A85-A85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3bbc00ebdd1ac32fa5f0ee77a0b9423
https://doi.org/10.1042/bst029a085a
https://doi.org/10.1042/bst029a085a