Výsledky vyhledávání - "Matthew F Rathgeber"

Akademický článek

Whole microbe arrays accurately predict interactions and overall antimicrobial activity of galectin-8 toward distinct strains of Streptococcus pneumoniae

Autor: Shang-Chuen Wu, Hau-Ming Jan, Mary L. Vallecillo-Zúniga, Matthew F. Rathgeber, Caleb S. Stowell, Kaleb L. Murdock, Kashyap R. Patel, Hirotomo Nakahara, Carter J. Stowell, Moon H. Nahm, Connie M. Arthur, Richard D. Cummings, Sean R. Stowell

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)

Abstract Microbial glycan microarrays (MGMs) populated with purified microbial glycans have been used to define the specificity of host immune factors toward microbes in a high throughput manner. However, a limitation of such arrays is that glycan pr

Externí odkaz: https://doaj.org/article/c4280ad7b7c745f8a5a8f62ba788f3bd

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Akademický článek

Treatment with galectin-1 improves myogenic potential and membrane repair in dysferlin-deficient models.

Autor: Mary L Vallecillo-Zúniga, Matthew F Rathgeber, P Daniel Poulson, Spencer Hayes, Jacob S Luddington, Hailie N Gill, Matthew Teynor, Braden C Kartchner, Jonard Valdoz, Caleb Stowell, Ashley R Markham, Connie Arthur, Sean Stowell, Pam M Van Ry

Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0238441 (2020)

Limb-girdle muscular dystrophy type 2B (LGMD2B) is caused by mutations in the dysferlin gene, resulting in non-functional dysferlin, a key protein found in muscle membrane. Treatment options available for patients are chiefly palliative in nature and

Externí odkaz: https://doaj.org/article/1b0d5091b3e842558ddcb01bd5b3fcc0

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Blood Group A Enhances SARS-CoV-2 Infection

Autor: Shang-Chuen Wu, Connie M. Arthur, Hau-Ming Jan, Wilfredo F Garcia-Beltran, Kashyap R. Patel, Matthew F. Rathgeber, Hans Verkerke, Narayanaiah Cheedarla, Ryan Philip Jajosky, Anu Paul, Andrew S. Neish, John D. Roback, Cassandra D. Josephson, Duane R. Wesemann, Daniel Kalman, Seth Rakoff-Nahoum, Richard D. Cummings, Sean R. Stowell

Publikováno v: Blood. 140:79-80

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c231f7c908c78ebba9fa687ed16a050
https://doi.org/10.1182/blood-2022-170083

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Therapeutic Benefit of Galectin-1: Beyond Membrane Repair, a Multifaceted Approach to LGMD2B

Autor: Hailie N. Gill, Mary L. Vallecillo-Zúniga, Matthew F. Rathgeber, Christian J Arnold, Spencer Hayes, Pam M. Van Ry, Braden C. Kartchner, Peter Daniel Poulson, Ethan L. Dodson, Jacob S. Luddington, Seth R. Garfield, Sean R. Stowell, Connie M Arthur, Jonathan L Spallino, Jonard Corpuz Valdoz

Publikováno v: Cells
Volume 10
Issue 11
Cells, Vol 10, Iss 3210, p 3210 (2021)

Two of the main pathologies characterizing dysferlinopathies are disrupted muscle membrane repair and chronic inflammation, which lead to symptoms of muscle weakness and wasting. Here, we used recombinant human Galectin-1 (rHsGal-1) as a therapeutic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d4d3f7638b2a6da765b7aea93af0f5

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Innate immune Galectin-7 specifically targets microbes that decorate themselves in blood group-like antigens

Autor: Shang-Chuen Wu, Nourine A. Kamili, Marcelo Dias-Baruffi, Cassandra D. Josephson, Matthew F. Rathgeber, Melissa Y. Yeung, William J. Lane, Jianmei Wang, Hau-Ming Jan, Seth Rakoff-Nahoum, Richard D. Cummings, Sean R. Stowell, Connie M. Arthur

Publikováno v: iScience. 25:104482

Adaptive immunity can target a nearly infinite range of antigens, yet it is tempered by tolerogenic mechanisms that limit autoimmunity. Such immunological tolerance, however, creates a gap in adaptive immunity against microbes decorated with self-lik

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1586e4ca11d505598d877df497670d37
https://doi.org/10.1016/j.isci.2022.104482

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