Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Matthew F Buas"'
Autor:
Pawadee Lohavanichbutr, Yuzheng Zhang, Pei Wang, Haiwei Gu, G A Nagana Gowda, Danijel Djukovic, Matthew F Buas, Daniel Raftery, Chu Chen
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204249 (2018)
Oral cavity squamous cell carcinoma (OCC) and oropharyngeal squamous cell carcinoma (OPC) are among the most common cancers worldwide and are associated with high mortality and morbidity. The purpose of this study is to identify potential biomarkers
Externí odkaz:
https://doaj.org/article/bc1b3055b0c548b9982b0d41aac06851
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143894 (2015)
IntroductionMicroRNAs (miRNAs) regulate messenger RNAs (mRNAs) and as such have been implicated in a variety of diseases, including cancer. MiRNAs regulate mRNAs through binding of the miRNA 5' seed sequence (~7-8 nucleotides) to the mRNA 3' UTRs; po
Externí odkaz:
https://doaj.org/article/24aa89f0794144ccb6b6a832509728f4
Autor:
Matthew F Buas, Lynn Onstad, David M Levine, Harvey A Risch, Wong-Ho Chow, Geoffrey Liu, Rebecca C Fitzgerald, Leslie Bernstein, Weimin Ye, Nigel C Bird, Yvonne Romero, Alan G Casson, Douglas A Corley, Nicholas J Shaheen, Anna H Wu, Marilie D Gammon, Brian J Reid, Laura J Hardie, Ulrike Peters, David C Whiteman, Thomas L Vaughan
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128617 (2015)
Incidence of esophageal adenocarcinoma (EA) has increased substantially in recent decades. Multiple risk factors have been identified for EA and its precursor, Barrett's esophagus (BE), such as reflux, European ancestry, male sex, obesity, and tobacc
Externí odkaz:
https://doaj.org/article/075fc38fcef04c84b2ed178bd1f2c3ac
Autor:
Mourad Wagdy Ali, Jianhong Chen, Li Yan, Xiaoyu Wang, James Y Dai, Thomas L Vaughan, Graham Casey, Matthew F Buas
Publikováno v:
Hum Mol Genet
Nineteen genetic susceptibility loci for esophageal adenocarcinoma (EAC) and its precursor Barrett’s esophagus (BE) have been identified through genome-wide association studies (GWAS). Clinical translation of such discoveries, however, has been hin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d53522082ed9e36a59b5ffa81f4c7c3
https://doi.org/10.1093/hmg/ddac141
https://doi.org/10.1093/hmg/ddac141
Autor:
Thomas L. Vaughan, David C. Whiteman, Laura J. Hardie, Brian J. Reid, Anna H. Wu, Nicholas J. Shaheen, Douglas A. Corley, Nigel C. Bird, Jesper Lagergren, Weimin Ye, Leslie Bernstein, Wong-Ho Chow, Harvey A. Risch, David M. Levine, Lynn E. Onstad, Matthew F. Buas, Jean de Dieu Tapsoba, James Y. Dai
Supplementary Table 1. Missing rates for three risk factors by study site in BEAGESS Supplementary Table 2. Genome-wide significant single nucleotide polymorphisms (SNPs) selected for GxE analysis. Supplementary Table 3. Odds ratios (95% confidence i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b72041864b52e9eee3c28ccd4ac2b85
https://doi.org/10.1158/1055-9965.22437069.v1
https://doi.org/10.1158/1055-9965.22437069.v1
Autor:
Thomas L. Vaughan, David C. Whiteman, Laura J. Hardie, Brian J. Reid, Anna H. Wu, Nicholas J. Shaheen, Douglas A. Corley, Nigel C. Bird, Jesper Lagergren, Weimin Ye, Leslie Bernstein, Wong-Ho Chow, Harvey A. Risch, David M. Levine, Lynn E. Onstad, Matthew F. Buas, Jean de Dieu Tapsoba, James Y. Dai
Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1733c3b298343f3092241c19901367b9
https://doi.org/10.1158/1055-9965.22437075
https://doi.org/10.1158/1055-9965.22437075
Autor:
Thomas L. Vaughan, David C. Whiteman, Laura J. Hardie, Brian J. Reid, Anna H. Wu, Nicholas J. Shaheen, Douglas A. Corley, Nigel C. Bird, Jesper Lagergren, Weimin Ye, Leslie Bernstein, Wong-Ho Chow, Harvey A. Risch, David M. Levine, Lynn E. Onstad, Matthew F. Buas, Jean de Dieu Tapsoba, James Y. Dai
Supplementary Figure S1. NIH Roadmap Epigenome Atlas characterization of genomic regions flanking rs2687201.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a826ec19a2002dec382c26535f33118
https://doi.org/10.1158/1055-9965.22437072.v1
https://doi.org/10.1158/1055-9965.22437072.v1
Autor:
Thomas L. Vaughan, David C. Whiteman, Laura J. Hardie, Brian J. Reid, Anna H. Wu, Nicholas J. Shaheen, Douglas A. Corley, Nigel C. Bird, Jesper Lagergren, Weimin Ye, Leslie Bernstein, Wong-Ho Chow, Harvey A. Risch, David M. Levine, Lynn E. Onstad, Matthew F. Buas, Jean de Dieu Tapsoba, James Y. Dai
Background: Important risk factors for esophageal adenocarcinoma and its precursor, Barrett's esophagus, include gastroesophageal reflux disease, obesity, and cigarette smoking. Recently, genome-wide association studies have identified seven germline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18c5509769154e6d3509dc03043eeec
https://doi.org/10.1158/1055-9965.c.6515706
https://doi.org/10.1158/1055-9965.c.6515706
Autor:
James Y. Dai, Matthew F. Buas, Graham Casey, Li Yan, Thomas L. Vaughan, Mourad Wagdy Ali, Jianhong Chen, Shruti G. Dighe
Publikováno v:
Hum Mol Genet
Genome-wide association studies (GWAS) have identified ~20 genetic susceptibility loci for esophageal adenocarcinoma (EAC), and its precursor, Barrett’s esophagus (BE). Despite such advances, functional/causal variants and gene targets at these loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac72d185bda0d8c1fc130ea85ff93671
https://doi.org/10.1093/hmg/ddab259
https://doi.org/10.1093/hmg/ddab259
Autor:
Priyanka Nandakumar, Rebecca C. Fitzgerald, Jue-Sheng Ong, Jiyuan An, Claire Palles, David A. Hinds, Aaron P. Thrift, Catherine M. Olsen, Puya Gharahkhani, Stuart MacGregor, Xikun Han, Ines Gockel, Matthew F. Buas, Janusz Jankowski, Matthew Law, Anne C. Böhmer, Thomas L. Vaughan, Rachel E. Neale, Bradley J. Kendall, Johannes Schumacher
Publikováno v:
Gut. 71:1053-1061
ObjectiveGastro-oesophageal reflux disease (GERD) has heterogeneous aetiology primarily attributable to its symptom-based definitions. GERD genome-wide association studies (GWASs) have shown strong genetic overlaps with established risk factors such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9daaf3d28ad17af7bf3c426e4179b4
https://doi.org/10.1136/gutjnl-2020-323906
https://doi.org/10.1136/gutjnl-2020-323906