Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Matthew E. Hubbard"'
Publikováno v:
Mathematics in Engineering, Vol 6, Iss 1, Pp 192-220 (2024)
In this article we consider the application of Euler's homogeneous function theorem together with Stokes' theorem to exactly integrate families of polynomial spaces over general polygonal and polyhedral (polytopic) domains in two and three dimensions
Externí odkaz:
https://doaj.org/article/ca2b9948c6594357a5d614b586e1c588
Autor:
Bethan Morris, Lee Curtin, Andrea Hawkins-Daarud, Matthew E. Hubbard, Ruman Rahman, Stuart J. Smith, Dorothee Auer, Nhan L. Tran, Leland S. Hu, Jennifer M. Eschbacher, Kris A. Smith, Ashley Stokes, Kristin R. Swanson, Markus R. Owen
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 5, Pp 4905-4941 (2020)
Glioblastomas (GBMs) are the most aggressive primary brain tumours and have no known cure. Each individual tumour comprises multiple sub-populations of genetically-distinct cells that may respond differently to targeted therapies and may contribute t
Externí odkaz:
https://doaj.org/article/99df14c01fe5480e95f2de48de682d3f
Publikováno v:
Computers & Mathematics with Applications. 78:2734-2745
This paper is concerned with the development and application of optimally efficient numerical methods for the simulation of vascular tumour growth. This model used involves the flow and interaction of four different, but coupled, phases which are eac
Autor:
Stuart Smith, Kristin R. Swanson, Andrea Hawkins-Daarud, Dorothee P. Auer, Ashley M. Stokes, Jennifer M. Eschbacher, Bethan Morris, Kris A. Smith, Nhan L. Tran, Ruman Rahman, Leland S. Hu, Lee Curtin, Markus R. Owen, Matthew E. Hubbard
Publikováno v:
Mathematical biosciences and engineering : MBE
Mathematical Biosciences and Engineering, Vol 17, Iss 5, Pp 4905-4941 (2020)
Mathematical Biosciences and Engineering, Vol 17, Iss 5, Pp 4905-4941 (2020)
Glioblastomas (GBMs) are the most aggressive primary brain tumours and have no known cure. Each individual tumour comprises multiple sub-populations of genetically-distinct cells that may respond differently to targeted therapies and may contribute t
Publikováno v:
Computers & Mathematics with Applications
Computers & Mathematics with Applications, Elsevier, 2020, ⟨10.1016/j.camwa.2019.09.019⟩
Computers & Mathematics with Applications, 2020, ⟨10.1016/j.camwa.2019.09.019⟩
Computers & Mathematics with Applications, Elsevier, 2020, ⟨10.1016/j.camwa.2019.09.019⟩
Computers & Mathematics with Applications, 2020, ⟨10.1016/j.camwa.2019.09.019⟩
International audience; This article investigates the potential for an r-adaptation algorithm to improve the efficiency of space-time residual distribution schemes in the approximation of time-dependent hyperbolic conservation laws, e.g. scalar advec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f967e16f360b6cdb7e98ad418abf7127
https://hal.inria.fr/hal-02310394/file/CAMWA-HRS19.pdf
https://hal.inria.fr/hal-02310394/file/CAMWA-HRS19.pdf
Publikováno v:
Lecture Notes in Computational Science and Engineering ISBN: 9783030307042
We use phase-field techniques coupled with a Coleman–Noll type procedure to derive a family of thermomechanically consistent models for predicting the evolution of a non-volatile thin liquid film on a flat substrate starting from mass conservation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c71efb289073fd14e34ed573ec6f2a2c
https://doi.org/10.1007/978-3-030-30705-9_11
https://doi.org/10.1007/978-3-030-30705-9_11
Autor:
Andrea Hawkins-Daarud, Dorothee P. Auer, Leland S. Hu, Bethan Morris, Lee Curtin, Nhan L. Tran, Bernard R. Bendok, Matthew E. Hubbard, Stuart Smith, Ruman Rahman, Maciej M. Mrugala, Jing Li, Kristin R. Swanson, Markus R. Owen
Publikováno v:
Neuro Oncol
Glioblastomas (GBMs) are known to be complex tumors comprising multiple subpopulations of genetically-distinct cancer cells; it is thought that this genetic variation is a major factor in the lack of observed survival benefit of treatment regimes tha
Autor:
Bindi S. Brook, Chris Twelves, Matthew E. Hubbard, Maria Jove, Stephen W. Smye, Reuben D. O'Dea, Roger M. Phillips, Elizabeth C. Holden, Paul M. Loadman, Jade A. Spencer
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 370(2)
Adequate drug distribution through tumors is essential for treatment to be effective. Palbociclib is a cyclin-dependent kinase 4/6 inhibitor approved for use in patients with hormone receptor positive, human epidermal growth factor receptor 2 negativ
Publikováno v:
Computer Methods in Applied Mechanics and Engineering. 309:554-578
In this work we consider the discretization of a recently formulated (Collis et al., [22]) multiscale model for drug- and nutrient-limited tumour growth. The key contribution of this work is the proposal of a discontinuous Galerkin finite element sch
Autor:
Paul M. Loadman, Chris J Twelves, Maria Jove, Roger M. Phillips, Matthew E. Hubbard, Steven W. Smye
Publikováno v:
Royal Society Open Science
Royal Society Open Science, Vol 4, Iss 5 (2017)
Royal Society Open Science, Vol 4, Iss 5 (2017)
The tumour vasculature and microenvironment is complex and heterogeneous, contributing to reduced delivery of cancer drugs to the tumour. We have developed an in silico model of drug transport in a tumour cord to explore the effect of different drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67403ecd6c650699d64ecde74337cbff
https://nottingham-repository.worktribe.com/file/861669/1/HJLPTS_supplement.pdf
https://nottingham-repository.worktribe.com/file/861669/1/HJLPTS_supplement.pdf