Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Matthew E. Handley"'
Autor:
Gabriele Pollara, Benjamin M. Chain, James Barnett, Manish Thakker, David R. Katz, Jane Rasaiyaah, Matthew E. Handley
Publikováno v:
International Immunology. 19:923-933
Dendritic cells (DCs) sense the presence of conserved microbial structures in their local microenvironment via specific pattern recognition receptors (PRRs). This leads to a programme of changes, which include migration and activation, and enables th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cef043ff696eef3511f30422fc53b7
https://doi.org/10.1093/intimm/dxm050
https://doi.org/10.1093/intimm/dxm050
Publikováno v:
International Journal of Experimental Pathology. 88:111-126
This review summarizes current knowledge about the mixed lineage kinases (MLKs) and explores their potential role in inflammation and immunity. MLKs were identified initially as signalling molecules in the nervous system. They were also shown to play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfb3e1cdcac7068651d11f32c0216149
https://doi.org/10.1111/j.1365-2613.2007.00531.x
https://doi.org/10.1111/j.1365-2613.2007.00531.x
Autor:
Gabriel Pollara, Claire A. Swetman Andersen, David R. Katz, Matthew E. Handley, Benjamin M. Chain, Anne J. Ridley
Publikováno v:
International Immunology. 18:1295-1303
The morphology of antigen-presenting dendritic cells (DCs) is characterized by the presence of numerous long dendrites. The formation of these processes is shown to require the interaction between the beta1-integrin (CD29) on the surface of the DCs a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0b56cedd6bef3ea5974156f945cf34
https://doi.org/10.1093/intimm/dxl062
https://doi.org/10.1093/intimm/dxl062
Publikováno v:
Scandinavian Journal of Immunology. 63:151-154
The central role of dendritic cells (DC) in the initiation of immune responses requires these cells to be able to determine the degree of danger in their microenvironment. Abrogating the activity of type I interferon (IFN) secreted after lipopolysacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528bed8fa3e564ff1c635d40da8a0375
https://doi.org/10.1111/j.1365-3083.2006.01727.x
https://doi.org/10.1111/j.1365-3083.2006.01727.x
Autor:
Matthew E. Handley, Manika Chaudry, Peter R Bunyard, Gabriel Pollara, John C. Foreman, David R. Katz, Charles J.J Alderman, Isabelle Wood, Benjamin M. Chain, Karine Rutault
Publikováno v:
Molecular Immunology. 39:815-827
Initiation of adaptive immunity requires activation of dendritic cells (DC) by "danger" signals. This study examines the functional consequences of activating a cellular stress response in human DC. Anisomycin, a potent inducer of this "stress" respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3e0a89a184f1ac0bd9910bc2c4217c
https://doi.org/10.1016/s0161-5890(02)00262-6
https://doi.org/10.1016/s0161-5890(02)00262-6
Publikováno v:
International journal of experimental pathology. 88(2)
This review summarizes current knowledge about the mixed lineage kinases (MLKs) and explores their potential role in inflammation and immunity. MLKs were identified initially as signalling molecules in the nervous system. They were also shown to play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::875e07f796b26ad7fefd003261575006
https://pubmed.ncbi.nlm.nih.gov/17408454
https://pubmed.ncbi.nlm.nih.gov/17408454
Publikováno v:
Free radical biologymedicine. 38(12)
Dendritic cells (DC) sense infection in their local microenvironment and respond appropriately in order to induce T cell immunity. This response is mediated in part via the mitogen-activated protein kinase (MAPK) pathways. Hydrogen peroxide is presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dec22c1b2cc866d35d13bd2895b6eaf
https://pubmed.ncbi.nlm.nih.gov/15917192
https://pubmed.ncbi.nlm.nih.gov/15917192
Autor:
Mansi Rajpopat, David R. Katz, Benjamin M. Chain, Gabriele Pollara, Meleri Jones, Robert S. Coffin, Matthew E. Handley, Graham R. Foster, Antonia Kwan
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 173(6)
Adaptive cellular immunity is required to clear HSV-1 infection in the periphery. Myeloid dendritic cells (DCs) are the first professional Ag-presenting cell to encounter the virus after primary and secondary infection and thus the consequences of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed841aef61e0467e52df50859483b05
https://pubmed.ncbi.nlm.nih.gov/15356161
https://pubmed.ncbi.nlm.nih.gov/15356161
Publikováno v:
Journal of immunological methods. 297(1-2)
The relationship between phagocytic capacity and morphology of dendritic cells (DCs) has not been investigated previously. Therefore, in order to approach this question, we have developed a novel assay, which is described here. The model of dendritic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d994588d2305b4ca7bc1503319e41c34
https://pubmed.ncbi.nlm.nih.gov/15777928
https://pubmed.ncbi.nlm.nih.gov/15777928
Autor:
Matthew E. Handley, Jane Rasaiyaah, James Barnett, Manish Thakker, Gabriele Pollara, David R. Katz, Benjamin M. Chain
Publikováno v:
International Immunology; Aug2007, Vol. 19 Issue 8, p923-923, 1p