Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Matthew E. Grunewald"'
Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses
Autor:
Jeremiah Athmer, Anthony R. Fehr, Matthew E. Grunewald, Wen Qu, D. Lori Wheeler, Kevin W. Graepel, Rudragouda Channappanavar, Aimee Sekine, Dana Saud Aldabeeb, Michael Gale, Mark R. Denison, Stanley Perlman
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Selective packaging is a mechanism used by multiple virus families to specifically incorporate genomic RNA (gRNA) into virions and exclude other types of RNA. Lineage A betacoronaviruses incorporate a 95-bp stem-loop structure, the packaging
Externí odkaz:
https://doaj.org/article/3da1a93d54de4efbb6a33718ce452b29
Publikováno v:
Journal of Virology
Coronaviruses are a family of positive-sense RNA viruses with human and agricultural significance. Characterizing the mechanisms by which coronavirus infection dictates pathogenesis or counters the host immune response would provide targets for the d
Publikováno v:
Coronaviruses ISBN: 9781071608999
Coronaviruses
Methods in Molecular Biology
Methods Mol Biol
Coronaviruses
Methods in Molecular Biology
Methods Mol Biol
Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized by club-like spikes that project from their surface, an unusually large RNA genome, and a unique replication strategy. CoVs cause a variety of diseases in mammals and birds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1cc4b3c9e1b4e23fb649eb03bf9589
https://doi.org/10.1007/978-1-0716-0900-2_1
https://doi.org/10.1007/978-1-0716-0900-2_1
Publikováno v:
Virology
ADP-ribosylation is a common post-translational modification, although how it modulates RNA virus infection is not well understood. While screening for ADP-ribosylated proteins during coronavirus (CoV) infection, we detected a ~55 kDa ADP-ribosylated
Autor:
Stanley Perlman, Takashi Maejima, Christopher S. Sullivan, Chad V. Kuny, Robert Lease, Dana Ferraris, Masanori Aikawa, Matthew E. Grunewald, Anthony R. Fehr, Yating Chen
Publikováno v:
PLOS Pathogens
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 5, p e1007756 (2019)
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 5, p e1007756 (2019)
ADP-ribosylation is a ubiquitous post-translational addition of either monomers or polymers of ADP-ribose to target proteins by ADP-ribosyltransferases, usually by interferon-inducible diphtheria toxin-like enzymes known as PARPs. While several PARPs
Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses
Autor:
Aimee Sekine, Matthew E. Grunewald, Jeremiah Athmer, Dana Aldabeeb, Kevin W. Graepel, Rudragouda Channappanavar, Wen Qu, D. Lori Wheeler, Anthony R. Fehr, Mark R. Denison, Michael Gale, Stanley Perlman
Publikováno v:
mBio, Vol 9, Iss 3, p e00272-18 (2018)
mBio, Vol 9, Iss 3 (2018)
mBio
mBio, Vol 9, Iss 3 (2018)
mBio
Selective packaging is a mechanism used by multiple virus families to specifically incorporate genomic RNA (gRNA) into virions and exclude other types of RNA. Lineage A betacoronaviruses incorporate a 95-bp stem-loop structure, the packaging signal (
Autor:
Samarchith P. Kurup, Jeremiah Athmer, Ann M. Janowski, Shuh Narumiya, Matthew E. Grunewald, Fayyaz S. Sutterwala, Anthony R. Fehr, Ramakrishna Sompallae, Dorthea L. Wheeler, David K. Meyerholz, Rahul Vijay, Stanley Perlman
Publikováno v:
Proceedings of the National Academy of Sciences
Prostaglandin D2 (PGD2), an eicosanoid with both pro- and anti-inflammatory properties, is the most abundantly expressed prostaglandin in the brain. Here we show that PGD2 signaling through the D-prostanoid receptor 1 (DP1) receptor is necessary for
Autor:
Jeremiah Athmer, Anthony R. Fehr, Everett Clinton Smith, Stanley Perlman, Mark R. Denison, Matthew E. Grunewald
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
mBio
mBio, Vol 8, Iss 1, p e02320-16 (2017)
mBio
mBio, Vol 8, Iss 1, p e02320-16 (2017)
Coronavirus (CoV) replication and transcription are carried out in close proximity to restructured endoplasmic reticulum (ER) membranes in replication/transcription complexes (RTC). Many of the CoV nonstructural proteins (nsps) are required for RTC f
Autor:
Matthew E Grunewald, Yating Chen, Chad Kuny, Takashi Maejima, Robert Lease, Dana Ferraris, Masanori Aikawa, Christopher S Sullivan, Stanley Perlman, Anthony R Fehr
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007756 (2019)
ADP-ribosylation is a ubiquitous post-translational addition of either monomers or polymers of ADP-ribose to target proteins by ADP-ribosyltransferases, usually by interferon-inducible diphtheria toxin-like enzymes known as PARPs. While several PARPs
Externí odkaz:
https://doaj.org/article/3626d2ff4f4b4dbeb2b06ed5db5433f6