Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Matthew E. Bender"'
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Akademický článek
A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer
Autor: Buse Eglenen-Polat, Ryan R. Kowash, Hai-Cheng Huang, Silvia Siteni, Mingrui Zhu, Kenian Chen, Matthew E. Bender, Ilgen Mender, Victor Stastny, Benjamin J. Drapkin, Prithvi Raj, John D. Minna, Lin Xu, Jerry W. Shay, Esra A. Akbay
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract There are few effective treatments for small cell lung cancer (SCLC) underscoring the need for innovative therapeutic approaches. This study focuses on exploiting telomerase, a critical SCLC dependency as a therapeutic target. A prominent ch
Externí odkaz: https://doaj.org/article/d143811484044c1b88f499b5d0432d04
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5
Data from Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis
Autor: Esra A. Akbay, Jane E. Johnson, John D. Minna, Atsushi Kumanogoh, Shohei Koyama, Kenneth E. Huffman, Trisha K. Savage, Yujiro Naito, Buse Eglenen-Polat, Rahul Kollipara, Luc Girard, Matthew E. Bender, Yi Huang, Mingrui Zhu
Small cell lung cancer (SCLC) is a pulmonary neuroendocrine cancer with very poor prognosis and limited effective therapeutic options. Most patients are diagnosed at advanced stages, and the exact reason for the aggressive and metastatic phenotype of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::743b7725c9eac0c376d8c0610effdf09
https://doi.org/10.1158/0008-5472.c.6513162.v1
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7
EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer
Autor: David E. Gerber, Esra A. Akbay, Farjana J. Fattah, Kathryn H. Dao, Bipasha Mukherjee, Chao Xing, Amyn A. Habib, Boning Gao, Shanrong Zhang, Matthew E. Bender, Kemp H. Kernstine, Cheng Ming Chiang, Ke Gong, John D. Minna, Gao Guo, Michael Peyton, Dawen Zhao, Nishah Panchani, Adwait Amod Sathe, Sandeep Burma
Publikováno v: Nature Cancer. 1:394-409
EGFR inhibition is an effective treatment in the minority of non-small cell lung cancer (NSCLC) cases harboring EGFR-activating mutations, but not in EGFR wild type (EGFRwt) tumors. Here, we demonstrate that EGFR inhibition triggers an antiviral defe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9724528c7c4d723be4111ff6bf382059
https://doi.org/10.1038/s43018-020-0048-0
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8
Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis
Autor: Atsushi Kumanogoh, Yujiro Naito, Trisha K. Savage, John D. Minna, Luc Girard, Esra A. Akbay, Mingrui Zhu, Shohei Koyama, Rahul K. Kollipara, Kenneth E. Huffman, Matthew E. Bender, Jane E. Johnson, Buse Eglenen-Polat, Yi Huang
Publikováno v: Cancer Res
Small cell lung cancer (SCLC) is a pulmonary neuroendocrine cancer with very poor prognosis and limited effective therapeutic options. Most patients are diagnosed at advanced stages, and the exact reason for the aggressive and metastatic phenotype of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b380962fcf619ca8f6c033de8323afb
https://pubmed.ncbi.nlm.nih.gov/33495232
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