Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Matthew E Merritt"'
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0281396 (2023)
Hypoxia is a common feature of most solid tumors, one that favors tumor progression and limits treatment effectiveness. Targeting hypoxia has long been a goal in cancer therapy, by identifying factors that reverse or ameliorate the effects of hypoxia
Externí odkaz:
https://doaj.org/article/ea66f2c0a6bb4c0db293fc62e9219b15
Autor:
Rohit Mahar, Mukundan Ragavan, Mario C. Chang, Savannah Hardiman, Nissin Moussatche, Adam Behar, Rolf Renne, Matthew E. Merritt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Oncolytic viral therapy is a recent advance in cancer treatment, demonstrating promise as a primary treatment option. To date, the secondary metabolic effects of viral infection in cancer cells has not been extensively studied. In this work,
Externí odkaz:
https://doaj.org/article/73e20652647c43a6985afe9e06614b7e
Autor:
Lucia Cilenti, Rohit Mahar, Jacopo Di Gregorio, Camilla T. Ambivero, Matthew E. Merritt, Antonis S. Zervos
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
MUL1 is a multifunctional E3 ubiquitin ligase that is involved in various pathophysiological processes including apoptosis, mitophagy, mitochondrial dynamics, and innate immune response. We uncovered a new function for MUL1 in the regulation of mitoc
Externí odkaz:
https://doaj.org/article/836e49a91fde481ba036d80a3b8bea90
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The role of ketones in metabolic health has progressed over the past two decades, moving from what was perceived as a simple byproduct of fatty acid oxidation to a central player in a multiplicity of disease states. Previous work with hyperpolarized
Externí odkaz:
https://doaj.org/article/7dcea9e8e1164c42887371db6f25119a
Autor:
John Kurhanewicz, Daniel B. Vigneron, Jan Henrik Ardenkjaer-Larsen, James A. Bankson, Kevin Brindle, Charles H. Cunningham, Ferdia A. Gallagher, Kayvan R. Keshari, Andreas Kjaer, Christoffer Laustsen, David A. Mankoff, Matthew E. Merritt, Sarah J. Nelson, John M. Pauly, Philips Lee, Sabrina Ronen, Damian J. Tyler, Sunder S. Rajan, Daniel M. Spielman, Lawrence Wald, Xiaoliang Zhang, Craig R. Malloy, Rahim Rizi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 1-16 (2019)
This white paper discusses prospects for advancing hyperpolarization technology to better understand cancer metabolism, identify current obstacles to HP (hyperpolarized) 13C magnetic resonance imaging’s (MRI’s) widespread clinical use, and provid
Externí odkaz:
https://doaj.org/article/84ebe3efefdc40839f297b3d92907a8a
Autor:
Chris E. Shannon, Mukundan Ragavan, Juan Pablo Palavicini, Marcel Fourcaudot, Terry M Bakewell, Ivan A. Valdez, Iriscilla Ayala, Eunsook S. Jin, Muniswamy Madesh, Xianlin Han, Matthew E. Merritt, Luke Norton
Publikováno v:
Molecular Metabolism, Vol 45, Iss , Pp 101154- (2021)
Objective: Insulin resistance and altered hepatic mitochondrial function are central features of type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD), but the etiological role of these processes in disease progression remains unclear.
Externí odkaz:
https://doaj.org/article/67c698d87fe047148632cbaa851c76cd
Autor:
Jiajun Lei, Rohit Mahar, Mario C. Chang, James Collins, Matthew E. Merritt, Timothy J. Garrett, Richard A. Yost
Publikováno v:
Analytical Chemistry. 95:1908-1915
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ecc9e6f2fdfc26659c9b35d3cae5b10
https://doi.org/10.1021/acs.analchem.2c03974
https://doi.org/10.1021/acs.analchem.2c03974
Autor:
Stephen J. Staklinski, Mario C. Chang, Rebecca C. Ahrens‐Nicklas, Shagun Kaur, Arianna K. Stefanatos, Elizabeth E. Dudenhausen, Matthew E. Merritt, Michael S. Kilberg
Publikováno v:
JIMD Reports. 64:167-179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73add010ee32f9c8183a68e638d70d44
https://doi.org/10.1002/jmd2.12356
https://doi.org/10.1002/jmd2.12356
Publikováno v:
Metabolites, Vol 11, Iss 7, p 441 (2021)
Type II diabetes and pre-diabetes are widely prevalent among adults. Elevated serum glucose levels are commonly treated by targeting hepatic gluconeogenesis for downregulation. However, direct measurement of hepatic gluconeogenic capacity is accompli
Externí odkaz:
https://doaj.org/article/65c2323104b642a9a64882bf82c951d5
Autor:
Jian Xu, Ralph J. DeBerardinis, Radek C. Skoda, Sean J. Morrison, Matthew E. Merritt, Min Ni, Weina Chen, Kathryn E. Dickerson, Junhua Lyu, Kailong Li, Xin Liu, Le Qi, Mingyi Chen, Alpaslan Tasdogan, Yuannyu Zhang, Hui Cao, Jakub Zmajkovic, McKenzie Patrick, Feng Cai, Yuxuan Liu, Zhimin Gu
Table S3 shows sequences of primers and shRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0b16941b1073821c5540fc6cfc00f2
https://doi.org/10.1158/2159-8290.22536193
https://doi.org/10.1158/2159-8290.22536193
